
A phageome is a community of
bacteriophage
A bacteriophage (), also known informally as a ''phage'' (), is a duplodnaviria virus that infects and replicates within bacteria and archaea. The term was derived from "bacteria" and the Greek φαγεῖν ('), meaning "to devour". Bacteri ...
s and their metagenomes localized in a particular environment, similar to a
microbiome. The term was first used in an article by Modi ''et al'' in 2013 and has continued to be used in scientific articles that relate to bacteriophages and their metagenomes. A
bacteriophage
A bacteriophage (), also known informally as a ''phage'' (), is a duplodnaviria virus that infects and replicates within bacteria and archaea. The term was derived from "bacteria" and the Greek φαγεῖν ('), meaning "to devour". Bacteri ...
, or phage for short, is a virus that has the ability to infect bacteria and archaea, and can replicate inside of them. Phageome is a subcategory of
virome, which is all of the viruses that are associated with a host or environment. Phages make up the majority of most viromes and are currently understood as being the most abundant organism. Oftentimes scientists will look only at a phageome instead of a virome while conducting research.
In humans
Although bacteriophages do not have the capability to infect human cells, they are found in abundance in the
human virome.
The human gut phageome has recently become a topic of interest in the scientific community. The makeup of the gut phageome can be responsible for different gut related diseases such as IBD. The composition of phages that make up a healthy human gut phageome is currently debated, since different methods of research can lead to different results.
[{{cite journal , vauthors = Shkoporov AN, Ryan FJ, Draper LA, Forde A, Stockdale SR, Daly KM, McDonnell SA, Nolan JA, Sutton TD, Dalmasso M, McCann A, Ross RP, Hill C , display-authors = 6 , title = Reproducible protocols for metagenomic analysis of human faecal phageomes , journal = Microbiome , volume = 6 , issue = 1 , pages = 68 , date = April 2018 , pmid = 29631623 , pmc = 5892011 , doi = 10.1186/s40168-018-0446-z ]
See also
*
Virosphere
Virosphere (virus diversity, virus world, global virosphere) is the viral part of the biosphere, namely the pool of viruses in all hosts and all environments on planet earth.
Virosphere may also refer to a pool of certain group of viruses accordin ...
References
Microbiology
Bacteriophages
Biology
Wikipedia Student Program
Microbiomes