Peter Guy Wolynes is an American theoretical chemist and physicist. Since 2011 he has been a Bullard-Welch Foundation Professor of Science and professor of chemistry at

Rice University William Marsh Rice University, commonly referred to as Rice University, is a Private university, private research university in Houston, Houston, Texas, United States. Established in 1912, the university spans 300 acres. Rice University comp ...

. He is widely recognized for his significant contributions to the theories of

protein folding Protein folding is the physical process by which a protein, after Protein biosynthesis, synthesis by a ribosome as a linear chain of Amino acid, amino acids, changes from an unstable random coil into a more ordered protein tertiary structure, t ...

glass Glass is an amorphous (non-crystalline solid, non-crystalline) solid. Because it is often transparency and translucency, transparent and chemically inert, glass has found widespread practical, technological, and decorative use in window pane ...

es, and gene networks. Previously he was James R. Eiszner Professor at the

University of Illinois at Urbana-Champaign The University of Illinois Urbana-Champaign (UIUC, U of I, Illinois, or University of Illinois) is a public land-grant research university in the Champaign–Urbana metropolitan area, Illinois, United States. Established in 1867, it is the f ...

, and the Francis H.C. Crick Chair of Physical Sciences at the

University of California, San Diego The University of California, San Diego (UC San Diego in communications material, formerly and colloquially UCSD) is a public university, public Land-grant university, land-grant research university in San Diego, California, United States. Es ...

Education and early life

Wolynes was born in Chicago, Illinois, on April 21, 1953. He graduated from

Indiana University Indiana University (IU) is a state university system, system of Public university, public universities in the U.S. state of Indiana. The system has two core campuses, five regional campuses, and two regional centers under the administration o ...

in 1971 with a B.A. in Chemistry, and from

Harvard University Harvard University is a Private university, private Ivy League research university in Cambridge, Massachusetts, United States. Founded in 1636 and named for its first benefactor, the History of the Puritans in North America, Puritan clergyma ...

with a Ph.D. in Chemical Physics in 1976.

Career and research

After a brief

postdoctoral research A postdoctoral fellow, postdoctoral researcher, or simply postdoc, is a person professionally conducting research after the completion of their doctoral studies (typically a PhD). Postdocs most commonly, but not always, have a temporary acade ...

Massachusetts Institute of Technology The Massachusetts Institute of Technology (MIT) is a Private university, private research university in Cambridge, Massachusetts, United States. Established in 1861, MIT has played a significant role in the development of many areas of moder ...

with

John Deutch John Mark Deutch (born July 27, 1938) is an American civil servant and physical chemist. He was the United States Deputy Secretary of Defense from 1994 to 1995 and Director of Central Intelligence (DCI) from May 10, 1995, until December 15, 1996 ...

, in the fall of 1976 he became an assistant professor at the chemistry department of Harvard University at the age of 23. In 1980 he moved to the University of Illinois, eventually becoming the Center for Advanced Study Professor of Chemistry, Physics and Biophysics. In 2000 he moved to the department of chemistry and biochemistry at the University of California, San Diego, as the Francis Crick Chair in the Physical Sciences. In addition to continuing his work on many body chemical physics, protein folding and structure prediction, he studied stochastic aspects of cell biology. In 2011 he moved to Rice University as the Bullard-Welch Foundation Professor of Science, and Professor of Chemistry and Physics. As for 2024, Peter Wolynes has published more than 460 research articles and has an h-index equal to 121 according to hi
Google Scholar profile
Energy landscape of protein folding: Wolynes is worldwide known in the field of biophysics by his Energy Landscapes Theory and the Principle of Minimal Frustration. This theory, that was published in 1987 together with Joseph Bryngelson, states that naturally evolved proteins have optimised their folding energy landscapes and that nature has chosen amino acid sequences so that the folded state of the protein is sufficiently stable. In addition, the acquisition of the folded state had to become a sufficiently fast process. Even though nature has reduced the level of frustration in proteins, some degree of it remains up to now as can be observed in the presence of local minima in the energy landscape of proteins.

Awards

He is a member of the

National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, NGO, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the ...

and the

German Academy of Sciences Leopoldina The German National Academy of Sciences Leopoldina (), in short Leopoldina, is the national academy of Germany, and is located in Halle (Saale). Founded on 1 January 1652, based on academic models in Italy, it was originally named the ''Academi ...

. He is a Fellow of the

American Physical Society The American Physical Society (APS) is a not-for-profit membership organization of professionals in physics and related disciplines, comprising nearly fifty divisions, sections, and other units. Its mission is the advancement and diffusion of ...

, the

Biophysical Society The Biophysical Society is an international scientific society whose purpose is to lead the development and dissemination of knowledge in biophysics. Founded in 1958, the Society currently consists of over 7,000 members in academia, government, an ...

, the

American Philosophical Society The American Philosophical Society (APS) is an American scholarly organization and learned society founded in 1743 in Philadelphia that promotes knowledge in the humanities and natural sciences through research, professional meetings, publicat ...

, the

American Academy of Arts and Sciences The American Academy of Arts and Sciences (The Academy) is one of the oldest learned societies in the United States. It was founded in 1780 during the American Revolution by John Adams, John Hancock, James Bowdoin, Andrew Oliver, and other ...

, and Foreign Member of the

Royal Society The Royal Society, formally The Royal Society of London for Improving Natural Knowledge, is a learned society and the United Kingdom's national academy of sciences. The society fulfils a number of roles: promoting science and its benefits, re ...

. In 2012, he received the ACS Award in Theoretical Chemistry.

References

{{DEFAULTSORT:Wolynes, Peter Guy 21st-century American chemists Foreign members of the Royal Society Fellows of the American Academy of Arts and Sciences Fellows of the American Physical Society Living people Indiana University alumni Harvard Graduate School of Arts and Sciences alumni Rice University faculty 1953 births Members of the United States National Academy of Sciences Foreign fellows of the Indian National Science Academy Santa Fe Institute people Members of the American Philosophical Society