Peficitinib (trade name Smyraf) is a pharmaceutical drug used for the treatment of

rheumatoid arthritis Rheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects synovial joint, joints. It typically results in warm, swollen, and painful joints. Pain and stiffness often worsen following rest. Most commonly, the wrist and ...

. It belongs to the class of drugs known as

Janus kinase inhibitor A Janus kinase inhibitor, also known as JAK inhibitor or jakinib, is a type of immune modulating medication, which inhibits the activity of one or more of the Janus kinase family of enzymes ( JAK1, JAK2, JAK3, TYK2), thereby interfering with the ...

s (JAK inhibitors). Peficitinib was approved for use in Japan in 2019.

References

Tyrosine kinase inhibitors Adamantanes Pyrrolopyridines Tertiary alcohols Disease-modifying antirheumatic drugs {{antineoplastic-drug-stub