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Peak inspiratory pressure (PIP) is the highest level of pressure applied to the
lung The lungs are the primary Organ (biology), organs of the respiratory system in many animals, including humans. In mammals and most other tetrapods, two lungs are located near the Vertebral column, backbone on either side of the heart. Their ...
s during
inhalation Inhalation (or inspiration) happens when air or other gases enter the lungs. Inhalation of air Inhalation of air, as part of the cycle of breathing, is a vital process for all human life. The process is autonomic (though there are exceptions ...
. In
mechanical ventilation Mechanical ventilation or assisted ventilation is the Medicine, medical term for using a ventilator, ventilator machine to fully or partially provide artificial ventilation. Mechanical ventilation helps move air into and out of the lungs, wit ...
the number reflects a positive pressure in centimeters of water pressure (cm H2O). In normal breathing, it may sometimes be referred to as the maximal inspiratory pressure (MIPO), which is a negative value. Peak inspiratory pressure increases with any airway resistance. Factors that may increase PIP include increased secretions, bronchospasm, biting down on ventilation tubing, and decreased lung compliance. PIP should never be chronically higher than 40 cm H2O unless the patient has acute respiratory distress syndrome.


See also

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Static compliance Lung compliance, or pulmonary compliance, is a measure of the lung's compliance (physiology), ability to stretch and expand (distensibility of elastic tissue). In clinical practice it is separated into two different measurements, static compliance ...
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Dynamic compliance Lung compliance, or pulmonary compliance, is a measure of the lung's ability to stretch and expand (distensibility of elastic tissue). In clinical practice it is separated into two different measurements, static compliance and dynamic compliance. ...


References

{{reflist Pulmonology Respiratory therapy Mechanical ventilation