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Patrick Holford is a British author and entrepreneur who endorses a range of controversial vitamin tablets. As an advocate of alternative nutrition and diet methods, he appears regularly on television and radio in the UK and abroad. He has 36 books in print in 29 languages. His business career promotes a wide variety of alternative medical approaches such as
orthomolecular medicine Orthomolecular medicine is a form of alternative medicine that aims to maintain human health through nutritional supplementation. The concept builds on the idea of an optimal nutritional environment in the body and suggests that diseases reflect ...
, many of which are considered
pseudoscientific Pseudoscience consists of statements, beliefs, or practices that claim to be both scientific and factual but are incompatible with the scientific method. Pseudoscience is often characterized by contradictory, exaggerated or unfalsifiable claim ...
by mainstream science and medicine. Holford's claims about HIV and
autism The autism spectrum, often referred to as just autism or in the context of a professional diagnosis autism spectrum disorder (ASD) or autism spectrum condition (ASC), is a neurodevelopmental condition (or conditions) characterized by difficulti ...
are not in line with modern medical thought, and have been criticised for putting people in danger and damaging public health. In 2006 Holford was discovered to be using his PR advisor to delete critical content from his Wikipedia page.


Career

Holford obtained a BSc in
experimental psychology Experimental psychology refers to work done by those who apply experimental methods to psychological study and the underlying processes. Experimental psychologists employ human participants and animal subjects to study a great many topics, in ...
from the
University of York , mottoeng = On the threshold of wisdom , established = , type = Public research university , endowment = £8.0 million , budget = £403.6 million , chancellor = Heather Melville , vice_chancellor = Charlie Jeffery , students ...
in 1979.Holford, Patrick.
Patrick Holford: Profile
' howtoquit.co.uk. Accessed 29 May 2009.
Doctored information on celebrity nutritionist
Ben Goldacre Ben Michael Goldacre (born 20 May 1974) is a British physician, academic and science writer. He is the first Bennett Professor of Evidence-Based Medicine and director of the Bennett Institute for Applied Data Science at the University of Oxford ...
,
The Guardian ''The Guardian'' is a British daily newspaper A newspaper is a periodical publication containing written information about current events and is often typed in black ink with a white or gray background. Newspapers can cover a wide ...
, 6 January 2007, retrieved 25 May 2010
As a psychology student, he became interested in the biochemistry of mental health problems. His research brought him in contact with Carl Pfeiffer and
Abram Hoffer Abram Hoffer (November 11, 1917 – May 27, 2009) was a Canadian biochemist, physician, and psychiatrist known for his "adrenochrome hypothesis" of schizoaffective disorders. According to Hoffer, megavitamin therapy and other nutritional intervent ...
, both of whom claimed success in treating
mental illness A mental disorder, also referred to as a mental illness or psychiatric disorder, is a behavioral or mental pattern that causes significant distress or impairment of personal functioning. Such features may be persistent, relapsing and remitt ...
with nutritional therapy. In 1984, Holford founded the Institute for Optimum Nutrition (ION). At that institute, he has worked on nutritional approaches to clinical depression,
schizophrenia Schizophrenia is a mental disorder characterized by continuous or relapsing episodes of psychosis. Major symptoms include hallucinations (typically hearing voices), delusions, and disorganized thinking. Other symptoms include social wi ...
, ADHD and
eating disorder An eating disorder is a mental disorder defined by abnormal eating behaviors that negatively affect a person's physical or mental health. Only one eating disorder can be diagnosed at a given time. Types of eating disorders include binge eating ...
s. In 1995, the Board of Trustees of ION (of which he was a director) awarded him an Honorary Diploma in Nutritional Therapy. He retired as Director of ION in 1998 and was awarded ION's Award for Excellence in 2009. He was the chief executive officer and co-founder (with Professor André Tylee of the
Institute of Psychiatry The Institute of Psychiatry, Psychology and Neuroscience (IoPPN) is a research institution dedicated to discovering what causes mental illness and diseases of the brain. In addition, its aim is to help identify new treatments for them and ways ...
) of the special interest group that developed into
Food for the Brain Foundation The Food for the Brain Foundation is a non-profit educational campaign, claiming to have been created by a group of nutritionists, doctors, psychiatrists, psychologists, teachers and scientists to promote a purported link between nutrition and ...
, a registered charity which has the stated aim of promoting mental health through nutrition. He was also director of the Brain Bio Centre, which specialises in a nutrition-based approach to
mental health Mental health encompasses emotional, psychological, and social well-being, influencing cognition, perception, and behavior. It likewise determines how an individual handles stress, interpersonal relationships, and decision-making. Mental hea ...
problems. Holford is a Fellow of the British Association for Nutritional Therapy (BANT), one of a number of professional bodies that seek to represent nutritional therapists in the UK.The British Association of Nutrition Therapy,
About BANT
. Retrieved 7 January 2007.
He is registered with the Complementary and Natural Healthcare Council. He is also the Patron of the South African Association of Nutritional Therapy and the Irish Association of Nutritional Therapy. Between 2007 and 2008 Holford was Visiting Professor at
Teesside University , mottoeng = Deeds Not Words , established = 1930 – Constantine Technical College1969 – as Teesside Polytechnic 1992 – gained university status , type = Public , endowment = £0.23 m (2019/20) , chancellor ...
and in 2007 was appointed as Head of Science and Education at Biocare, a nutritional supplement company. Holford has 36 books in print in 29 languages.


Criticism

Holford has been the subject of criticism for his promotion of medically dubious techniques and products including
hair analysis Hair analysis may refer to the chemical analysis of a hair sample, but can also refer to microscopic analysis or comparison. Chemical hair analysis may be considered for retrospective purposes when blood and urine are no longer expected to cont ...
, his support of the now struck off doctor
Andrew Wakefield Andrew Jeremy Wakefield (born September 3, 1956) is a British anti-vaccine activist, former physician, and discredited academic who was struck off the medical register for his involvement in ''The Lancet'' MMR autism fraud, a 1998 study that ...
, and advocating the use of "non-drug alternatives for mental health" for which he has been given an award by the
Church of Scientology The Church of Scientology is a group of interconnected corporate entities and other organizations devoted to the practice, administration and dissemination of Scientology, which is variously defined as a cult, a business, or a new religious ...
-backed
Citizens Commission on Human Rights The Citizens Commission on Human Rights International (CCHR) is a nonprofit organization established in 1969 by the Church of Scientology and psychiatrist Thomas Szasz, headquartered in Los Angeles, California. Its stated mission is to "eradicate ...
. In 2006 Patrick Holford was discovered to be using his PR advisor to delete content on his Wikipedia page which was critical.


HIV

Holford's claim in ''The New Optimum Nutrition Bible'' that "
AZT Zidovudine (ZDV), also known as azidothymidine (AZT), is an antiretroviral medication used to prevent and treat HIV/AIDS. It is generally recommended for use in combination with other antiretrovirals. It may be used to prevent mother-to-child ...
, the first prescribable anti-HIV drug, is potentially harmful, and proving less effective than
vitamin C Vitamin C (also known as ascorbic acid and ascorbate) is a water-soluble vitamin found in citrus and other fruits and vegetables, also sold as a dietary supplement and as a topical 'serum' ingredient to treat melasma (dark pigment spots) a ...
" has been criticised by
Ben Goldacre Ben Michael Goldacre (born 20 May 1974) is a British physician, academic and science writer. He is the first Bennett Professor of Evidence-Based Medicine and director of the Bennett Institute for Applied Data Science at the University of Oxford ...
.Goldacre, Ben.
Vitamin deficiency
. ''The Guardian'', 6 January 2005. Retrieved 6 January 2007.
Goldacre writes that Holford based this conclusion on a non-clinical study where "you tip lots of vitamin C onto HIV-infected cells and measure a few things related to HIV replication".Goldacre, Ben.

. ''The Guardian'', 20 January 2005. Retrieved 6 January 2007.
Goldacre notes that the paper does not compare vitamin C to AZT for efficacy. He argues that "Holford was guilty of at least incompetence in claiming that this study demonstrated vitamin C to be a better treatment than AZT." Prof
David Colquhoun David Colquhoun (born 19 July 1936) is a British pharmacologist at University College London (UCL). He has contributed to the general theory of receptor and synaptic mechanisms, and in particular the theory and practice of single ion channel f ...
argues that Holford's "advocacy of vitamin C as better than conventional drugs to treat Aids is truly scary". Holford repliedHolford, Patrick
Letter to ''The Guardian''
16 February 2007. Retrieved 19 March 2007.
to ''
The Guardian ''The Guardian'' is a British daily newspaper A newspaper is a periodical publication containing written information about current events and is often typed in black ink with a white or gray background. Newspapers can cover a wide ...
'' newspaper that:
"As oldacrewell knows, the author of the research – Dr Raxit Jariwalla – wrote to the ''Guardian'' (January 20, 2005) the last time Goldacre made this claim, to confirm that my statement is correct on the basis of two on-clinicalstudies on HIV-infected cells. The real crime here is that no full-scale human trials have been funded on vitamin C to follow up Jariwalla's important finding because it is non-patentable and hence not profitable. Goldacre seems unconcerned about the way commercial interests distort scientific research."
Goldacre replied that Raxit Jariwalla was a senior researcher at the Rath Research Institute in California – connected to vitamin salesman
Matthias Rath Matthias Rath (born 1955) is a doctor, businessman, and vitamin salesman. He earned his medical degree in Germany. Rath claims that a program of dietary supplement, nutritional supplements (which he calls "cellular medicine"), including formulati ...
. Matthias Rath has been linked to the previous policy of the South African government to deny anti-viral drugs to HIV positive patients.


Autism

Holford believes that there is a potential link in some susceptible children between the
MMR vaccine The MMR vaccine is a vaccine against measles, mumps, and rubella (German measles), abbreviated as ''MMR''. The first dose is generally given to children around 9 months to 15 months of age, with a second dose at 15 months to 6 years of age, w ...
and the development of autism-like symptoms. This is against the overwhelming consensus of the scientific community and many high-quality empirical studies that demonstrate there is no such link. The Wakefield ''et al.'' paper upon which this hypothesis was based has been discredited by the scientific community, was retracted from the journal, and 10 of the 12 co-authors have formally disavowed the paper's conclusions. Furthermore,
Centers for Disease Control and Prevention The Centers for Disease Control and Prevention (CDC) is the national public health agency of the United States. It is a United States federal agency, under the Department of Health and Human Services, and is headquartered in Atlanta, Georg ...
, the Institute of Medicine of the
National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the Nat ...
, the UK
National Health Service The National Health Service (NHS) is the umbrella term for the publicly funded healthcare systems of the United Kingdom (UK). Since 1948, they have been funded out of general taxation. There are three systems which are referred to using the " ...
and the Cochrane Library review have all concluded that there is no evidence of a link between the MMR vaccine and autism. (See
MMR vaccine controversy Claims of a link between the MMR vaccine and autism have been extensively investigated and found to be false. The link was first suggested in the early 1990s and came to public notice largely as a result of the 1998 ''Lancet'' MMR autism fraud ...
) The Cochrane Library's systematic review also concluded that "The design and reporting of safety outcomes in MMR vaccine studies, both pre- and post- marketing, are largely inadequate...." Nonetheless, it noted that the vaccine has prevented diseases that still carry a heavy burden of death and complications, and that the lack of confidence in the vaccine has damaged public health. Catherine Collins, chief
dietician A dietitian, medical dietitian, or dietician is an expert in identifying and treating disease-related malnutrition and in conducting medical nutrition therapy, for example designing an enteral tube feeding regimen or mitigating the effects of ...
at
St George's Hospital St George's Hospital is a large teaching hospital in Tooting, London. Founded in 1733, it is one of the UK's largest teaching hospitals and one of the largest hospitals in Europe. It is run by the St George's University Hospitals NHS Foundatio ...
, reported that after following Holford's advice to adopt a restricted diet, a young
autistic The autism spectrum, often referred to as just autism or in the context of a professional diagnosis autism spectrum disorder (ASD) or autism spectrum condition (ASC), is a neurodevelopmental condition (or conditions) characterized by difficulti ...
girl participating in one of Holford's experiments suffered dramatic weight loss and sleep problems. Holford dismissed the allegations as "professional jealousy", stating that "This girl hasn't suffered. She's got better and is behaving better. Her parents are delighted with the results. It's only Catherine Collins who is not." Holford claimed that the girl was already a poor sleeper, and that when placed on a less restrictive diet, she was able to regain the weight she had lost.


Advertising

There has also been an adjudication by the Advertising Standards Authority against Patrick Holford's 100% Health leaflet. "On this point, the ad breached CAP Code clauses 3.1 (Substantiation), 7.1 (Truthfulness), 50.1 (Health & beauty products and therapies – General) and 50.20 (Health & beauty products and therapies – Vitamins, minerals and other
food supplement A dietary supplement is a manufactured product intended to supplement one's diet by taking a pill, capsule, tablet, powder, or liquid. A supplement can provide nutrients either extracted from food sources or that are synthetic in orde ...
s)." A previous adjudication by the ASA also went against Mr Holford. . Mr Holford has also been the subject of at least two adverse rulings by the Advertising Standards Authority of South Africa.http://www.quackdown.info/article/tag/Holford/>


Books


References


Further reading

* Goldacre, Ben (2008). '' Bad Science''. HarperPerennial. * Thompson, Damian (2008). '' Counterknowledge: How We Surrendered to Conspiracy Theories, Quack Medicine, Bogus Science and Fake History''. Atlantic Books.


External links


Patrick Holford's Website

Ben Goldacre's blog posts on Patrick Holford
{{DEFAULTSORT:Holford, Patrick Year of birth missing (living people) Living people Alternative medicine activists Alumni of the University of York British nutritionists Orthomolecular medicine advocates Pseudoscientific diet advocates