Patricia Anastastia Martin DeLeon (born 13 July 1944) is a Jamaican reproductive geneticist who is specialists in the

male reproductive system The male reproductive system consists of a number of sex organs that play a role in the process of human reproduction. These organs are located on the outside of the body, and within the pelvic cavity, pelvis. The main male sex organs are the hu ...

. She is the Trustees Distinguished Professor of Biological Sciences at the

University of Delaware The University of Delaware (colloquially known as UD, UDel, or Delaware) is a Statutory college#Delaware, privately governed, state-assisted Land-grant university, land-grant research university in Newark, Delaware, United States. UD offers f ...

. In 2010 she was awarded the

Presidential Award for Excellence in Science, Mathematics, and Engineering Mentoring The Presidential Award for Excellence in Science, Mathematics and Engineering Mentoring (PAESMEM) is a Presidential award established by the United States White House in 1995. The program is administered by the National Science Foundation (NSF) on ...

Barack Obama Barack Hussein Obama II (born August 4, 1961) is an American politician who was the 44th president of the United States from 2009 to 2017. A member of the Democratic Party, he was the first African American president in American history. O ...

Early life and education

DeLeon was born in

Port Maria Port Maria () is the capital town of the Jamaican parish of Saint Mary Parish, Jamaica, Saint Mary. Originally named "Puerto Santa Maria", it was the second town established by Spanish settlers in Jamaica. The ruins of Fort Haldane, built 1759, ...

. She was one of nine children, and had to lobby the principal of her high school, Excelsior High School, to waive the fees to allow her family to attend. She became interested in botany as a child and learnt the Latin names of all the plants that she collected. The principal agreed based on DeLeon's academic performance. She attended the

University of the West Indies The University of the West Indies (UWI), originally University College of the West Indies, is a public university system established to serve the higher education needs of the residents of 18 English-speaking countries and territories in t ...

for her undergraduate studies, where she focussed on zoology and chemistry. After earning her undergraduate degree DeLeon moved to

Canada Canada is a country in North America. Its Provinces and territories of Canada, ten provinces and three territories extend from the Atlantic Ocean to the Pacific Ocean and northward into the Arctic Ocean, making it the world's List of coun ...

, where she joined the

University of Western Ontario The University of Western Ontario (UWO; branded as Western University) is a Public university, public research university in London, Ontario, Canada. The main campus is located on of land, surrounded by residential neighbourhoods and the Thame ...

for her doctoral degree in microscopic anatomy. She was subsequently a postdoc at

McGill University McGill University (French: Université McGill) is an English-language public research university in Montreal, Quebec, Canada. Founded in 1821 by royal charter,Frost, Stanley Brice. ''McGill University, Vol. I. For the Advancement of Learning, ...

Research and career

In 1976 DeLeon joined the faculty at the

. DeLeon has extensively studied the Sperm adhesion molecule 1 (SPAM1), a

glycosylphosphatidylinositol Glycosylphosphatidylinositol () or glycophosphatidylinositol (GPI) is a phosphoglyceride that can be attached to the C-terminus of a protein during posttranslational modification. The resulting GPI-anchored proteins play key roles in a wide vari ...

linked membrane protein. The mechanisms that underpin the expression of these proteins are poorly understood, but are crucial for the development of

assisted reproductive technology Assisted reproductive technology (ART) includes medical procedures used primarily to address infertility. This subject involves procedures such as in vitro fertilization (IVF), intracytoplasmic sperm injection (ICSI), and cryopreservation of ga ...

. The over-expression of SPAM1 can give rise to cancer. In 2009 she was named the Trustees Distinguished Professor of Biological Sciences. Alongside her work on male fertility, DeLeon has studied particles in the

fallopian tube The fallopian tubes, also known as uterine tubes, oviducts or salpinges (: salpinx), are paired tubular sex organs in the human female body that stretch from the Ovary, ovaries to the uterus. The fallopian tubes are part of the female reproduct ...

, the understanding of which may improve the outcomes of ''in vitro'' fertilisation. She is working on non-invasive diagnostic methods to identify embryos that are most likely to result in successful

IVF In vitro fertilisation (IVF) is a process of fertilisation in which an egg is combined with sperm in vitro ("in glass"). The process involves monitoring and stimulating the ovulatory process, then removing an ovum or ova (egg or eggs) from t ...

. Throughout her career DeLeon has worked to support undergraduates gain research experience.

Awards and honours

* 2006 Elected to the Executive Council of the American Society of Andrology * 2007

* 2010 William G. Demas Memorial Lecture * 2011 Caribbean Women in Science Medalist * 2012 50 Most Outstanding Jamaican Women * 2017 Francis Alison Faculty Award

Selected publications

* * *

References

{{DEFAULTSORT:DeLeon, Patricia Jamaican women academics American people of Jamaican descent University of Delaware faculty University of the West Indies alumni University of Western Ontario alumni 1944 births Living people