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Pathological science is an area of research where "people are tricked into false results ... by subjective effects, wishful thinking or threshold interactions."Irving Langmuir, "Colloquium on Pathological Science," held at the Knolls Research Laboratory, December 18, 1953. A recording of the actual talk was made, but apparently lost, though a recorded transcript was produced by Langmuir a few months later.
transcript is available
on the Web site of Kenneth Steiglitz, Professor of Computer Science, Princeton University. But see also: I. Langmuir, "Pathological Science", General Electric, (Distribution Unit, Bldg. 5, Room 345, Research and Development Center, P.O. Box 8, Schenectady, NY 12301), 68-C-035 (1968); I. Langmuir,
Pathological Science
, (1989) ''Physics Today'', Volume 42, Issue 10, October 1989, pp. 36–48
The term was first used by Irving Langmuir,
Nobel Prize The Nobel Prizes ( ; ; ) are awards administered by the Nobel Foundation and granted in accordance with the principle of "for the greatest benefit to humankind". The prizes were first awarded in 1901, marking the fifth anniversary of Alfred N ...
-winning
chemist A chemist (from Greek ''chēm(ía)'' alchemy; replacing ''chymist'' from Medieval Latin ''alchemist'') is a graduated scientist trained in the study of chemistry, or an officially enrolled student in the field. Chemists study the composition of ...
, during a 1953 colloquium at the Knolls Research Laboratory. Langmuir said a pathological science is an area of research that simply will not "go away"—long after it was given up on as "false" by the majority of scientists in the field. He called pathological science "the science of things that aren't so." In his 2002 book, ''Undead Science'', sociology and anthropology Professor Bart Simon lists it among practices that are falsely perceived or presented to be science, "categories ... such as ...
pseudoscience Pseudoscience consists of statements, beliefs, or practices that claim to be both scientific and factual but are incompatible with the scientific method. Pseudoscience is often characterized by contradictory, exaggerated or unfalsifiable cl ...
, amateur science, deviant or fraudulent science, bad science, junk science, pathological science, cargo cult science, and voodoo science." Examples of pathological science include the
Martian canals During the late 19th and early 20th centuries, it was erroneously believed that there were "canals" on the planet Mars. These were a network of long straight lines in the equatorial regions from 60° north to 60° south latitude on Mars, observ ...
, N-rays, polywater, and
cold fusion Cold fusion is a hypothesized type of nuclear reaction that would occur at, or near, room temperature. It would contrast starkly with the nuclear fusion, "hot" fusion that is known to take place naturally within Main sequence, stars and artific ...
. The theories and conclusions behind all of these examples are currently rejected or disregarded by the majority of scientists.


Definition

Pathological science, as defined by Langmuir, is a psychological process in which a scientist, originally conforming to the
scientific method The scientific method is an Empirical evidence, empirical method for acquiring knowledge that has been referred to while doing science since at least the 17th century. Historically, it was developed through the centuries from the ancient and ...
, unconsciously veers from that method, and begins a pathological process of wishful data interpretation . Some characteristics of pathological science are: * The maximum effect that is observed is produced by a causative agent of barely detectable intensity, and the magnitude of the effect is substantially independent of the intensity of the cause. * The effect is of a magnitude that remains close to the limit of detectability, or multiple measurements are necessary because of the low
statistical significance In statistical hypothesis testing, a result has statistical significance when a result at least as "extreme" would be very infrequent if the null hypothesis were true. More precisely, a study's defined significance level, denoted by \alpha, is the ...
of the results. * There are claims of great accuracy. * Fantastic theories contrary to experience are suggested. * Criticisms are met by
ad hoc ''Ad hoc'' is a List of Latin phrases, Latin phrase meaning literally for this. In English language, English, it typically signifies a solution designed for a specific purpose, problem, or task rather than a Generalization, generalized solution ...
excuses. * The ratio of supporters to critics rises and then falls gradually to oblivion. Langmuir never intended the term to be rigorously defined; it was simply the title of his talk on some examples of "weird science". As with any attempt to define the scientific endeavor, examples and counterexamples can always be found.


Langmuir's examples


N-rays

Langmuir's discussion of N-rays has led to their traditional characterization as an instance of pathological science. In 1903, Prosper-René Blondlot was working on
X-ray An X-ray (also known in many languages as Röntgen radiation) is a form of high-energy electromagnetic radiation with a wavelength shorter than those of ultraviolet rays and longer than those of gamma rays. Roughly, X-rays have a wavelength ran ...
s (as were other physicists of the era) and noticed a new visible radiation that could penetrate
aluminium Aluminium (or aluminum in North American English) is a chemical element; it has chemical symbol, symbol Al and atomic number 13. It has a density lower than that of other common metals, about one-third that of steel. Aluminium has ...
. He devised experiments in which a barely visible object was illuminated by these N-rays, and thus became "more visible". Blondlot claimed that N-rays were causing a small visual reaction, too small to be seen under normal illumination, but just visible when most normal light sources were removed and the target was just barely visible to begin with. N-rays became the topic of some debate within the science community. After a time, American physicist Robert W. Wood decided to visit Blondlot's lab, which had moved on to the physical characterization of N-rays. An experiment passed the rays from a 2 mm slit through an aluminum prism, from which he was measuring the index of refraction to a precision that required measurements accurate to within 0.01 mm. Wood asked how it was possible that he could measure something to 0.01 mm from a 2 mm source, a physical impossibility in the propagation of any kind of wave. Blondlot replied, "That's one of the fascinating things about the N-rays. They don't follow the ordinary laws of science that you ordinarily think of." Wood then asked to see the experiments being run as usual, which took place in a room required to be very dark so the target was barely visible. Blondlot repeated his most recent experiments and got the same results—despite the fact that Wood had reached over and covertly sabotaged the N-ray apparatus by removing the prism.


Other examples

Langmuir offered additional examples of what he regarded as pathological science in his original speech: * The Davis–Barnes effect (1929; after Professor Bergen Davis from Columbia University) * Mitogenetic rays (1923; Alexander Gurwitsch and others) * The Allison effect (1927; after Fred Allison). (b) (c) (d) (e) * Extrasensory perception (1934), where
Rhine The Rhine ( ) is one of the List of rivers of Europe, major rivers in Europe. The river begins in the Swiss canton of Graubünden in the southeastern Swiss Alps. It forms part of the Swiss-Liechtenstein border, then part of the Austria–Swit ...
consciously discarded contrary test results because he felt they could not be correct.


Later examples

A 1985 version of Langmuir's speech offered more examples, although at least one of these (polywater) occurred entirely after Langmuir's death in 1957: * Water dowsing *
Martian canals During the late 19th and early 20th centuries, it was erroneously believed that there were "canals" on the planet Mars. These were a network of long straight lines in the equatorial regions from 60° north to 60° south latitude on Mars, observ ...
(Observed in late 19th century and early 20th century, they turned out to be optical illusions.) * Certain reported photomechanical and electromechanical effects * Polywater * Biological effects of magnetic fields (see magnetobiology and magnet therapy) except magnetoception


Newer examples

Since Langmuir's original talk, a number of newer examples of what appear to be pathological science have appeared. Denis Rousseau, one of the main debunkers of polywater, gave an update of Langmuir in 1992, and he specifically cited as examples the cases of polywater, Martin Fleischmann's cold fusion and Jacques Benveniste's "infinite dilution".


Polywater

Polywater was a form of water which appeared to have a much higher
boiling point The boiling point of a substance is the temperature at which the vapor pressure of a liquid equals the pressure surrounding the liquid and the liquid changes into a vapor. The boiling point of a liquid varies depending upon the surrounding envi ...
and much lower
freezing point The melting point (or, rarely, liquefaction point) of a substance is the temperature at which it changes state of matter, state from solid to liquid. At the melting point the solid and liquid phase (matter), phase exist in Thermodynamic equilib ...
than normal water. During the 1960s, a number of articles were published on the subject, and research on polywater was done around the world with mixed results. Eventually it was determined that some of the properties of polywater could be explained by biological contamination. When more rigorous cleaning of glassware and experimental controls were introduced, polywater could no longer be produced. It took several years for the concept of polywater to die in spite of the later negative results.


Cold fusion

In 1989, Martin Fleischmann and Stanley Pons announced the discovery of a simple and cheap procedure to obtain room-temperature
nuclear fusion Nuclear fusion is a nuclear reaction, reaction in which two or more atomic nuclei combine to form a larger nuclei, nuclei/neutrons, neutron by-products. The difference in mass between the reactants and products is manifested as either the rele ...
. Although there were multiple instances where successful results were reported, they lacked consistency and hence cold fusion came to be considered to be an example of pathological science. Two panels convened by the
US Department of Energy US or Us most often refers to: * Us (pronoun), ''Us'' (pronoun), the objective case of the English first-person plural pronoun ''we'' * US, an abbreviation for the United States US, U.S., Us, us, or u.s. may also refer to: Arts and entertainme ...
, one in 1989 and a second in 2004, did not recommend a dedicated federal program for cold fusion research. A small number of researchers continue working in the field.


Water memory

Jacques Benveniste was a French immunologist who in 1988 published a paper in the prestigious scientific journal ''
Nature Nature is an inherent character or constitution, particularly of the Ecosphere (planetary), ecosphere or the universe as a whole. In this general sense nature refers to the Scientific law, laws, elements and phenomenon, phenomena of the physic ...
'' describing the action of high dilutions of anti-IgE antibody on the degranulation of human basophils, findings which seemed to support the concept of
homeopathy Homeopathy or homoeopathy is a pseudoscientific system of alternative medicine. It was conceived in 1796 by the German physician Samuel Hahnemann. Its practitioners, called homeopaths or homeopathic physicians, believe that a substance that ...
. Biologists were puzzled by Benveniste's results, as only molecules of water, and no molecules of the original antibody, remained in these high dilutions. Benveniste concluded that the configuration of molecules in water was biologically active. Subsequent investigations have not supported Benveniste's findings.


See also

* Fringe science * Protoscience * Research Integrity Risk Index * Scientific misconduct ** List of experimental errors and frauds in physics ** List of topics characterized as pseudoscience


Notes


References

* Carroll, Robert Todd,
pathological science
. ''The Skeptic's Dictionary''. * * Kirby, Geoff.,

, ''New Scientist'', 24 February 1990 * Kowalski, Ludwik,
Pathological Science
(N-rays story). Montclair State University, Upper Montclair, N.J. * Langmuir, I. and R. N. Hall.,

. Colloquium at The Knolls Research Laboratory, December 18, 1953. * Langmuir, Irving, and Robert N. Hall. "Pathological science". '' Physics Today'' 42 (10): 36–48. 1989. * Turro, Nicholas J.,
Toward a general theory of pathological science
. ''21stC'': Issue 3.4 ''Strange Science''. * Wilson, James R.,

. Department of Industrial Engineering,
North Carolina State University North Carolina State University (NC State, North Carolina State, NC State University, or NCSU) is a public university, public Land-grant university, land-grant research university in Raleigh, North Carolina, United States. Founded in 1887 and p ...
. Raleigh, North Carolina. * Wynne, B.,
G. G. Barkla and the J-Phenomenon: a Case Study of the Treatment of Deviance in Physics
, ''Social Studies of Science'', Vol. 6, 1976, pp. 307–304 (abstract) {{DEFAULTSORT:Pathological Science Academic publishing Scholarly communication Science communication News media manipulation