Para-aminoblebbistatin 2D Structure
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''para''-Aminoblebbistatin is a water-soluble, non-fluorescent, photostable
myosin II Myosins () are a family of motor proteins (though most often protein complexes) best known for their roles in muscle contraction and in a wide range of other motility processes in eukaryotes. They are ATP-dependent and responsible for actin-ba ...
inhibitor, developed from blebbistatin. Among the several blebbistatin derivatives it is one of the most promising for research applications. Furthermore, it has a favourable overall profile considering inhibitory properties and
ADME ADME is the four-letter abbreviation (acronym) for absorption (pharmacokinetics), ''absorption'', distribution (pharmacology), ''distribution'', ''metabolism'', and ''excretion'', and is mainly used in fields such as pharmacokinetics and pharmacol ...
calculations.


Myosin specificity


References

{{DEFAULTSORT:Aminoblebbistatin, para- 4-Aminophenyl compounds Pyrroloquinolines Acyloins Tertiary alcohols