Pantopon, also known as Opium Alkaloids Hydrochlorides, is a preparation of

opiates An opiate is an alkaloid substance derived from opium (or poppy straw). It differs from the similar term ''opioid'' in that the latter is used to designate all substances, both natural and synthetic, that bind to opioid receptors in the brain ( ...

made up of all of the

alkaloids Alkaloids are a broad class of naturally occurring organic compounds that contain at least one nitrogen atom. Some synthetic compounds of similar structure may also be termed alkaloids. Alkaloids are produced by a large variety of organisms i ...

present in

opium Opium (also known as poppy tears, or Lachryma papaveris) is the dried latex obtained from the seed Capsule (fruit), capsules of the opium poppy ''Papaver somniferum''. Approximately 12 percent of opium is made up of the analgesic alkaloid mor ...

in their natural proportions as

hydrochloride In chemistry, a hydrochloride is an acid salt resulting, or regarded as resulting, from the reaction of hydrochloric acid with an organic base (e.g. an amine). An alternative name is chlorhydrate, which comes from French. An archaic alternati ...

salts In chemistry, a salt or ionic compound is a chemical compound consisting of an assembly of positively charged ions ( cations) and negatively charged ions (anions), which results in a compound with no net electric charge (electrically neutral). ...

. It can sometimes be tolerated by people who are allergic to

morphine Morphine, formerly also called morphia, is an opiate that is found naturally in opium, a dark brown resin produced by drying the latex of opium poppies (''Papaver somniferum''). It is mainly used as an analgesic (pain medication). There are ...

. Pantopon is prepared by treating standardized medicinal opium with

hydrochloric acid Hydrochloric acid, also known as muriatic acid or spirits of salt, is an aqueous solution of hydrogen chloride (HCl). It is a colorless solution with a distinctive pungency, pungent smell. It is classified as a acid strength, strong acid. It is ...

or, more commonly, mixing 20 parts morphine HCl, 5 parts codeine, 6 parts thebaine, 8 parts noscapine, 2 parts narcotine, 6 parts miscellaneous alkaloids hydrochlorides. Pantopon is, in other words,

with all of the tar and other insolubles removed in an injectable form which, by weight, is nearly as potent as

. It was invented in 1909 by the

Hoffmann-La Roche F. Hoffmann-La Roche AG, commonly known as Roche (), is a Swiss multinational holding healthcare company that operates worldwide under two divisions: Pharmaceuticals and Diagnostics. Its holding company, Roche Holding AG, has shares listed on ...

pharmaceutical company. Other drugs of the same type have included in the opium alkaloid

hydrobromide In chemistry, a hydrobromide is an acid salt resulting, or regarded as resulting, from the reaction of hydrobromic acid with an organic base (e.g. an amine). The compounds are similar to hydrochlorides. Some drugs are formulated as hydrobromides, ...

sulfate The sulfate or sulphate ion is a polyatomic anion with the empirical formula . Salts, acid derivatives, and peroxides of sulfate are widely used in industry. Sulfates occur widely in everyday life. Sulfates are salts of sulfuric acid and many ...

phosphates Phosphates are the naturally occurring form of the element phosphorus. In chemistry, a phosphate is an anion, salt, functional group or ester derived from a phosphoric acid. It most commonly means orthophosphate, a derivative of orthophosphor ...

, and

valerates Valeric acid or pentanoic acid is a straight-chain alkyl carboxylic acid with the chemical formula . Like other low-molecular-weight carboxylic acids, it has an unpleasant odor. It is found in the perennial flowering plant ''Valeriana officina ...

. "Opium in a syringe " and "Injectable Whole Opium" were common advertising slogans for the product from Roche. An example of similar product to Pantopon is Omnopon, which contains morphine, codeine, and papaverine.

Society and culture

Pantopon gave its name to the poem "Pantopon Rose" by the American writer

William Burroughs William Seward Burroughs II (; February 5, 1914 – August 2, 1997) was an American writer and visual artist. He is widely considered a primary figure of the Beat Generation and a major postmodern author who influenced popular culture and ...

and to a song with the same name by the

Northern Ireland Northern Ireland ( ; ) is a Countries of the United Kingdom, part of the United Kingdom in the north-east of the island of Ireland. It has been #Descriptions, variously described as a country, province or region. Northern Ireland shares Repub ...

alternative metal Alternative metal (also known as alt-metal) is a genre of heavy metal music that combines heavy metal with influences from alternative rock and other genres not normally associated with metal. Alternative metal bands are often characterized by ...

band

Therapy? Therapy? are a Northern Irish rock band from Larne, formed in 1989 by guitarist-vocalist Andy Cairns and drummer-vocalist Fyfe Ewing. Therapy? recorded their first demo with Cairns filling in on bass guitar. To complete the lineup, the band ...

on their 1994 album ''

Troublegum ''Troublegum'' is the second major label album by the Northern Irish rock band Therapy? It was released on 7 February 1994 via A&M Records. The album features a more punk-oriented style compared to the likes of Stiff Little Fingers, the Underton ...

''. Pantopon also gave its name to the 1996

Mexican Mexican may refer to: Mexico and its culture *Being related to, from, or connected to the country of Mexico, in North America ** People *** Mexicans, inhabitants of the country Mexico and their descendants *** Mexica, ancient indigenous people ...

documentary ''Rosa Pantopon''.''Rosa Pantopon''
on IMDB

References

Opiates {{alkaloid-stub