BRN-3 is a group of related
transcription factor
In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription (genetics), transcription of genetics, genetic information from DNA to messenger RNA, by binding t ...
s in the
POU family.
They are also known as class 4 POU domain
homeobox
A homeobox is a Nucleic acid sequence, DNA sequence, around 180 base pairs long, that regulates large-scale anatomical features in the early stages of embryonic development. Mutations in a homeobox may change large-scale anatomical features of ...
proteins.
There are three BRN-3 proteins encoded by the following genes:
* BRN3A (
POU4F1, )
* BRN3B (
POU4F2, )
* BRN3C (
POU4F3, )
Nomenclature
The BRN or Brn prefix is an abbreviation for "brain"; the longer name is "Brain-specific homeobox". The name of the group may also be abbreviated as POU4, Pou4, POU IV, or POU-IV.
References
External links
*
Transcription factors
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