Oxinium
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Oxinium is the brand name of a material used for
replacement joint Joint replacement is a procedure of orthopedic surgery known also as arthroplasty, in which an arthritic or dysfunctional joint surface is replaced with an orthopedic prosthesis. Joint replacement is considered as a treatment when severe joint p ...
s manufactured by the reconstructive
orthopedic surgery Orthopedic surgery or orthopedics ( alternative spelling orthopaedics) is the branch of surgery concerned with conditions involving the musculoskeletal system. Orthopedic surgeons use both surgical and nonsurgical means to treat musculoskeletal ...
division of medical devices company Smith & Nephew. It consists of a
zirconium Zirconium is a chemical element; it has Symbol (chemistry), symbol Zr and atomic number 40. First identified in 1789, isolated in impure form in 1824, and manufactured at scale by 1925, pure zirconium is a lustrous transition metal with a greyis ...
alloy An alloy is a mixture of chemical elements of which in most cases at least one is a metal, metallic element, although it is also sometimes used for mixtures of elements; herein only metallic alloys are described. Metallic alloys often have prop ...
metal substrate that transitions into a ceramic zirconium oxide outer surface. The ceramic surface is extremely abrasion resistant compared to traditional metal implant materials such as cobalt chromium. It also has a lower coefficient of friction against ultra-high molecular weight polyethylene (
UHMWPE Ultra-high-molecular-weight polyethylene (UHMWPE, UHMW) is a subset of the thermoplastic polyethylene. Also known as high-modulus polyethylene (HMPE), it has extremely long chains, with a molecular mass typically between 2 and 6 million amu. The l ...
), the typical counterface material used in total joint replacements. These two factors likely contribute to the significantly lower UHMWPE wear rates observed in simulator testing. Reducing UHMWPE wear is thought to decrease the risk of implant failure due to
osteolysis Osteolysis is an active resorption of bone matrix by osteoclasts and can be interpreted as the reverse of ossification. Although osteoclasts are active during the natural formation of healthy bone the term "osteolysis" specifically refers to a pat ...
. All-ceramic materials can have a similar effect on reducing wear, but are brittle and difficult to manufacture. The metal substrate of Oxinium implants makes components easier to manufacture and gives them greater toughness (a combination of strength and ductility). In essence, this technology combines the abrasion resistance and low friction of a ceramic with the workability and toughness of a metal. This combination of properties led to Oxinium technology being the first ever implant-related technology to win the prestigious
ASM International ASM International N.V. (with ASM standing for Advanced Semiconductor Materials) is a Dutch-headquartered multinational corporation that designs, manufactures, sells, and services equipment used in the fabrication of semiconductor devices. Its ...
Engineering Materials Achievement Award (EMAA) in 2005.{{fact, date=September 2012 Current competitive reduced-wear options in total hip arthroplasty (THA) are
ceramic A ceramic is any of the various hard, brittle, heat-resistant, and corrosion-resistant materials made by shaping and then firing an inorganic, nonmetallic material, such as clay, at a high temperature. Common examples are earthenware, porcela ...
-on-ceramic,
metal A metal () is a material that, when polished or fractured, shows a lustrous appearance, and conducts electrical resistivity and conductivity, electricity and thermal conductivity, heat relatively well. These properties are all associated wit ...
-on-metal, and metal-on-cross-linked
polyethylene Polyethylene or polythene (abbreviated PE; IUPAC name polyethene or poly(methylene)) is the most commonly produced plastic. It is a polymer, primarily used for packaging (plastic bags, plastic films, geomembranes and containers including bott ...
. The only competitive reduced-wear option for total knee arthroplasty (TKA) is metal-on-cross-linked polyethylene. In September 2003, Smith & Nephew recalled its Macrotextured Oxinium Profix and Genesis II knee implants because of reports that 30 people receiving the implants without bone cement had to undergo a replacement surgery after they became loose.Knee implant recall hits Smith & Nephew
The Guardian ''The Guardian'' is a British daily newspaper. It was founded in Manchester in 1821 as ''The Manchester Guardian'' and changed its name in 1959, followed by a move to London. Along with its sister paper, ''The Guardian Weekly'', ''The Guardi ...
, eptember 18, 2003/ref>


References


External links


Smith & Nephew Corporate Website
Biomaterials Implants (medicine) Zirconium alloys