An osmometer is a device for measuring the
osmotic strength
Osmotic concentration, formerly known as osmolarity, is the measure of solute concentration, defined as the number of osmoles (Osm) of solute per litre (L) of solution (osmol/L or Osm/L). The osmolarity of a solution is usually expressed as Osm/L ...
of a
solution
Solution may refer to:
* Solution (chemistry), a mixture where one substance is dissolved in another
* Solution (equation), in mathematics
** Numerical solution, in numerical analysis, approximate solutions within specified error bounds
* Solutio ...
,
colloid
A colloid is a mixture in which one substance consisting of microscopically dispersed insoluble particles is suspended throughout another substance. Some definitions specify that the particles must be dispersed in a liquid, while others exten ...
, or
compound
Compound may refer to:
Architecture and built environments
* Compound (enclosure), a cluster of buildings having a shared purpose, usually inside a fence or wall
** Compound (fortification), a version of the above fortified with defensive struct ...
.
There are several different techniques employed in osmometry:
*
Vapor pressure osmometers determine the concentration of osmotically active particles that reduce the
vapor pressure
Vapor pressure (or vapour pressure in English-speaking countries other than the US; see spelling differences) or equilibrium vapor pressure is defined as the pressure exerted by a vapor in thermodynamic equilibrium with its condensed phase ...
of a solution.
*
Membrane osmometers
A membrane osmometer is a device used to indirectly measure the number average molecular weight (M_n) of a polymer sample. One chamber contains pure solvent and the other chamber contains a solution in which the solute is a polymer with an unknown ...
measure the
osmotic pressure
Osmotic pressure is the minimum pressure which needs to be applied to a solution to prevent the inward flow of its pure solvent across a semipermeable membrane.
It is also defined as the measure of the tendency of a solution to take in a pure ...
of a solution separated from pure solvent by a semipermeable membrane.
*
Freezing point depression osmometers may also be used to determine the osmotic strength of a solution, as osmotically active compounds depress the
freezing point
The melting point (or, rarely, liquefaction point) of a substance is the temperature at which it changes state from solid to liquid. At the melting point the solid and liquid phase exist in equilibrium. The melting point of a substance depe ...
of a solution.
Osmometers are useful for determining the total concentration of dissolved
salts
In chemistry, a salt is a chemical compound consisting of an ionic assembly of positively charged cations and negatively charged anions, which results in a compound with no net electric charge. A common example is table salt, with positively ...
and
sugars
Sugar is the generic name for sweet-tasting, soluble carbohydrates, many of which are used in food. Simple sugars, also called monosaccharides, include glucose, fructose, and galactose. Compound sugars, also called disaccharides or double ...
in
blood
Blood is a body fluid in the circulatory system of humans and other vertebrates that delivers necessary substances such as nutrients and oxygen to the cells, and transports metabolic waste products away from those same cells. Blood in th ...
or
urine
Urine is a liquid by-product of metabolism in humans and in many other animals. Urine flows from the kidneys through the ureters to the urinary bladder. Urination results in urine being excreted from the body through the urethra.
Cellular ...
samples. Osmometry is also useful in determining the
molecular weight
A molecule is a group of two or more atoms held together by attractive forces known as chemical bonds; depending on context, the term may or may not include ions which satisfy this criterion. In quantum physics, organic chemistry, and bioch ...
of unknown compounds and polymers.
Osmometry is the measurement of the
osmotic strength
Osmotic concentration, formerly known as osmolarity, is the measure of solute concentration, defined as the number of osmoles (Osm) of solute per litre (L) of solution (osmol/L or Osm/L). The osmolarity of a solution is usually expressed as Osm/L ...
of a substance.
This is often used by chemists for the determination of average
molecular weight
A molecule is a group of two or more atoms held together by attractive forces known as chemical bonds; depending on context, the term may or may not include ions which satisfy this criterion. In quantum physics, organic chemistry, and bioch ...
.
See also
*
Clifton nanolitre osmometer
The freezing point depression osmometer is an osmometer that is used in determining a solution's osmotic concentration as its osmotically active aspects depress its freezing point. Osmometry further involves other techniques that including membr ...
, an example of a freezing point depression osmometer.
References
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Scientific techniques
Measuring instruments
Polymer chemistry
Amount of substance