Orthogonal Signal Correction (OSC) is a spectral preprocessing technique that removes variation from a data matrix X that is
orthogonal
In mathematics, orthogonality is the generalization of the geometric notion of '' perpendicularity''.
By extension, orthogonality is also used to refer to the separation of specific features of a system. The term also has specialized meanings in ...
to the response matrix Y. OSC was introduced by researchers at the
University of Umea
A university () is an institution of higher (or tertiary) education and research which awards academic degrees in several academic disciplines. ''University'' is derived from the Latin phrase ''universitas magistrorum et scholarium'', which rou ...
in 1998 and has since found applications in domains including
metabolomics
Metabolomics is the scientific study of chemical processes involving metabolites, the small molecule substrates, intermediates, and products of cell metabolism. Specifically, metabolomics is the "systematic study of the unique chemical fingerprin ...
.
References
Signal processing
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