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Phenylephrine/ketorolac, sold under the brand name Omidria, is a
combination drug A combination drug is a combination of two or more pharmaceutical drugs as active ingredients combined into a single dosage form, typically as a ''fixed-dose combination'', with each constituent standardized to specifications of a fixed dose. Fix ...
used during
cataract surgery Cataract surgery, also called lens replacement surgery, is the removal of the natural lens (anatomy), lens of the human eye, eye that has developed a cataract, an opaque or cloudy area. The eye's natural lens is usually replaced with an artific ...
or
intraocular lens An intraocular lens (IOL) is a lens (optics), lens implanted in the human eye, eye usually as part of a treatment for cataracts or for correcting other vision problems such as myopia, near-sightedness (myopia) and farsightedness, far-sightednes ...
replacement to prevent
intraoperative The perioperative period is the period of a patient's surgical procedure. It commonly includes ward admission, anesthesia, surgery, and recovery. Perioperative may refer to the three phases of surgery: preoperative, intraoperative, and postoperat ...
miosis Miosis, or myosis (), is excessive constriction of the pupil.Farlex medical dictionary
citing: ...
and to reduce
postoperative pain Pain is a distressing feeling often caused by intense or damaging stimuli. The International Association for the Study of Pain defines pain as "an unpleasant sensory and emotional experience associated with, or resembling that associated with, ...
. It contains
phenylephrine Phenylephrine, sold under the brand names Neosynephrine and Sudafed PE among others, is a medication used as a decongestant for uncomplicated nasal congestion in the form of a nasal spray or oral tablet, to dilate the pupil, to increase bloo ...
and
ketorolac Ketorolac, sold under the brand name Toradol, Acular and Sprix, among others, is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain. Specifically it is recommended for moderate to severe pain. Recommended duration of treatment is l ...
. Phenylephrine/ketorolac was approved for medical use in the United States in May 2014, and in the European Union in July 2015.


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* Alpha-1 adrenergic receptor agonists Combination drugs Nonsteroidal anti-inflammatory drugs Ophthalmology drugs Vasoconstrictors {{pharma-stub