Office Of Portfolio Analysis
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The Office of Portfolio Analysis was established in the
Division of Program Coordination, Planning, and Strategic Initiatives The Division of Program Coordination, Planning, and Strategic Initiatives (DPCPSI) is a division of the Office of the Director of the National Institutes of Health of the United States of America. DPCPSI was formally established as part of implemen ...
in 2011 to assist
NIH The National Institutes of Health (NIH) is the primary agency of the United States government responsible for biomedical and public health research. It was founded in 1887 and is part of the United States Department of Health and Human Service ...
Institutes and Centers with scientific portfolio analysis. Per the Federal Register, the Office of Portfolio Analysis serves the following goals: # Prepare and analyze data on NIH sponsored biomedical research to inform trans-NIH planning and coordination; # Serve as a resource for portfolio management at the programmatic level; # Employ databases, analytic tools, methodologies and other resources to conduct assessments in support of portfolio analyses and priority setting in scientific areas of interest across NIH; # Research and develop new analytic tools, support systems, and specifications for new resources in coordination with other NIH organizations to enhance the management of the NIH's scientific portfolio; and # Provide, in coordination with other NIH organizations, training on portfolio analysis tools, procedures, and methodology. After its establishment in 2011, George Santangelo was appointed as the first Director of the Office of Portfolio Analysis.


Analytic tools


NIH COVID-19 Portfolio

In response to the
COVID-19 pandemic The COVID-19 pandemic (also known as the coronavirus pandemic and COVID pandemic), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), began with an disease outbreak, outbreak of COVID-19 in Wuhan, China, in December ...
, the Office of Portfolio Analysis developed th
NIH COVID-19 Portfolio
to index and track ongoing
COVID-19 Coronavirus disease 2019 (COVID-19) is a contagious disease caused by the coronavirus SARS-CoV-2. In January 2020, the disease spread worldwide, resulting in the COVID-19 pandemic. The symptoms of COVID‑19 can vary but often include fever ...
research and disseminate it to the public. This portfolio is curated by scientific experts for COVID-19 relevance, and includes both peer-reviewed publications indexed in
PubMed PubMed is an openly accessible, free database which includes primarily the MEDLINE database of references and abstracts on life sciences and biomedical topics. The United States National Library of Medicine (NLM) at the National Institute ...
and
preprints In academic publishing, a preprint is a version of a scholarly or scientific paper that precedes formal peer review and publication in a peer-reviewed scholarly or scientific journal. The preprint may be available, often as a non-typeset versio ...
from
bioRxiv bioRxiv (pronounced "bio-archive") is an open access preprint repository for the biological sciences co-founded by John Inglis and Richard Sever in November 2013. It was hosted by Cold Spring Harbor Laboratory (CSHL) until March 11, 2025, whe ...
,
medRxiv medRxiv (pronounced "med-archive") is an online disciplinary repository publishing preprints in all disciplines of the health sciences. It distributes papers in the areas of medicine and clinical research without charge to the reader. In Janua ...
,
chemRxiv ChemRxiv (pronounced "chem archive"—the X represents the Greek letter chi ‡ is an open access preprint archive for chemistry. It is operated by the American Chemical Society, Royal Society of Chemistry and German Chemical Society. The new pr ...
,
arXiv arXiv (pronounced as "archive"—the X represents the Chi (letter), Greek letter chi ⟨χ⟩) is an open-access repository of electronic preprints and postprints (known as e-prints) approved for posting after moderation, but not Scholarly pee ...
,
SSRN The Social Science Research Network (SSRN) is an open access research platform that functions as a repository for sharing early-stage research and the rapid dissemination of scholarly research in the social sciences, humanities, life sciences, ...
, and Research Square.


''iCite''

The NIH developed
iCite
' as a
bibliometrics Bibliometrics is the application of statistical methods to the study of bibliographic data, especially in scientific and library and information science contexts, and is closely associated with scientometrics (the analysis of scientific metri ...
dashboard to freely disseminate article-level
citation metrics Citation impact or citation rate is a measure of how many times an academic journal article or book or author is cited by other articles, books or authors. Citation counts are interpreted as measures of the impact or influence of academic work a ...
for
scientific publications Scientific literature encompasses a vast body of academic papers that spans various disciplines within the natural and social sciences. It primarily consists of academic papers that present original empirical research and theoretical con ...
that are indexed in
PubMed PubMed is an openly accessible, free database which includes primarily the MEDLINE database of references and abstracts on life sciences and biomedical topics. The United States National Library of Medicine (NLM) at the National Institute ...
. One stated purpose of this analytic tool was to replace the use of journal level metrics like the
Journal Impact Factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a type of journal ranking. Journals with higher impact factor values are considered more prestigious or important within their field. The Impact Factor of a journ ...
in research assessment and portfolio analysis. Bulk data are made available through database snapshots and an API

As of 2020, '' iCite'' hosts three modules focusing on different types of citation metrics:


Influence

The research community called for the use of article-level citation metrics for research assessment instead of journal-level metrics, in the
San Francisco Declaration on Research Assessment The San Francisco Declaration on Research Assessment (DORA) is a statement that denounces the practice of correlating the journal impact factor to the merits of a specific scientist's contributions. Also according to this statement, this practice ...
. The influence module of ''iCite'' disseminates field- and time-normalized article-level citation metrics like the Relative Citation Ratio.


Translation

Because the
NIH The National Institutes of Health (NIH) is the primary agency of the United States government responsible for biomedical and public health research. It was founded in 1887 and is part of the United States Department of Health and Human Service ...
is particularly focused on science that improves human health, it developed article-level metrics that track the dissemination of basic research findings into clinical research, a process known as
bench to bedside Translational medicine (often called translational science, of which it is a form) develops the clinical practice applications of the basic science aspects of the biomedical sciences; that is, it translates basic science to applied science in medic ...
translation. The Translation module of ''iCite'' shows which clinical research articles have cited a given publication. For those publications that are not yet cited by a clinical research article, the Translation module shows the Approximate Potential to Translate, which is a
machine learning Machine learning (ML) is a field of study in artificial intelligence concerned with the development and study of Computational statistics, statistical algorithms that can learn from data and generalise to unseen data, and thus perform Task ( ...
estimate of the probability that the publication will be cited by a clinical research article in the future.


Citations

In order to maximize transparency, the Office of Portfolio Analysis generated a public-domain citation graph named the NIH Open Citation Collection. This citation graph underpins all citation metrics disseminated in ''iCite'', and sources citation data from several sources, as well as extracting references from the PDFs of
open access Open access (OA) is a set of principles and a range of practices through which nominally copyrightable publications are delivered to readers free of access charges or other barriers. With open access strictly defined (according to the 2001 de ...
articles.


References

{{reflist National Institutes of Health 2011 establishments in the United States