Odontogenic Infection
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An odontogenic infection is an
infection An infection is the invasion of tissue (biology), tissues by pathogens, their multiplication, and the reaction of host (biology), host tissues to the infectious agent and the toxins they produce. An infectious disease, also known as a transmis ...
that originates within a
tooth A tooth (: teeth) is a hard, calcified structure found in the jaws (or mouths) of many vertebrates and used to break down food. Some animals, particularly carnivores and omnivores, also use teeth to help with capturing or wounding prey, tea ...
or in the closely surrounding tissues. The term is derived from '' odonto-'' (
Ancient Greek Ancient Greek (, ; ) includes the forms of the Greek language used in ancient Greece and the classical antiquity, ancient world from around 1500 BC to 300 BC. It is often roughly divided into the following periods: Mycenaean Greek (), Greek ...
: , – 'tooth') and '' -genic'' (Ancient Greek: , ; – 'birth'). The most common causes for odontogenic infection to be established are dental caries, deep fillings, failed root canal treatments, periodontal disease, and pericoronitis. Odontogenic infection starts as localised infection and may remain localised to the region where it started, or spread into adjacent or distant areas. It is estimated that 90–95% of all orofacial infections originate from the teeth or their supporting structures and are the most common infections in the oral and maxilofacial region. Odontogenic infections can be severe if not treated and are associated with mortality rate of 10 to 40%. Furthermore, about 70% of odontogenic infections occur as periapical inflammation, i.e. acute periapical periodontitis or a periapical abscess. The next most common form of odontogenic infection is the periodontal abscess. Despite being more common in underprivileged regions, odontogenic infections affect people from all over the world, even in developed countries. __TOC__


Odontogenic sinusitis

Sinusitis Sinusitis, also known as rhinosinusitis, is an inflammation of the mucous membranes that line the sinuses resulting in symptoms that may include production of thick nasal mucus, nasal congestion, facial congestion, facial pain, facial pressure ...
is inflammation of the paranasal air sinuses. Odontogenic sinusitis is an inflammatory condition of the paranasal sinuses that is the result of dental pathology, most often resulting from prior dentoalveolar procedures, infections of maxillary dentition, or maxillary dental trauma. Infections associated with teeth may be responsible for approximately 20% of cases of maxillary sinusitis. The cause of this situation is usually a periapical or periodontal infection of a maxillary posterior tooth, where the inflammatory exudate has eroded through the bone superiorly to drain into the
maxillary sinus The pyramid-shaped maxillary sinus (or antrum of Nathaniel Highmore (surgeon), Highmore) is the largest of the paranasal sinuses, located in the maxilla. It drains into the middle meatus of the noseHuman Anatomy, Jacobs, Elsevier, 2008, page 209- ...
. Medical management and treatment of the underlying dental pathology remains a critical initial step in the treatment of odontogenic sinusitis, however recent literature suggests that a significant portion of patients may require endoscopic sinus surgery for successful disease resolution. Once an odontogenic infection involves the maxillary sinus, it is possible that it may then spread to the
orbit In celestial mechanics, an orbit (also known as orbital revolution) is the curved trajectory of an object such as the trajectory of a planet around a star, or of a natural satellite around a planet, or of an artificial satellite around an ...
or to the ethmoid sinus.


Complications of Odontogenic Infection

Odontogenic infection can be managed relatively easily if treated in the early stages of infection. However, there are some factors which need to be taken in consideration when dealing with odontogenic infection. A major complicating factor for managing odontogenic infections is the host defence mechanism which can be impaired by systemic illnesses and certain medications. The table below shows the most common causes for an impaired defence mechanism. If treatment is delayed, odontogenic infection can spread into adjacent tissues consequently leading to life-threatening conditions. Most commonly resulting in respiratory obstruction and
sepsis Sepsis is a potentially life-threatening condition that arises when the body's response to infection causes injury to its own tissues and organs. This initial stage of sepsis is followed by suppression of the immune system. Common signs and s ...
, and less commonly endocarditis, necrotising fasciitis, spondylitis,
brain abscess The brain is an organ that serves as the center of the nervous system in all vertebrate and most invertebrate animals. It consists of nervous tissue and is typically located in the head ( cephalization), usually near organs for special sense ...
, descending mediastinitis, thoracic empyema, pleuropulmonary suppuration,
aspiration pneumonia Aspiration pneumonia is a type of lung infection that is due to a relatively large amount of material from the stomach or mouth entering the lungs. Signs and symptoms often include fever and cough of relatively rapid onset. Complications may incl ...
,
pneumothorax A pneumothorax is collection of air in the pleural space between the lung and the chest wall. Symptoms typically include sudden onset of sharp, one-sided chest pain and dyspnea, shortness of breath. In a minority of cases, a one-way valve is ...
, mandibular or cervical
osteomyelitis Osteomyelitis (OM) is the infectious inflammation of bone marrow. Symptoms may include pain in a specific bone with overlying redness, fever, and weakness. The feet, spine, and hips are the most commonly involved bones in adults. The cause is ...
, abscess of the carotid sheath and jugular
thrombophlebitis Thrombophlebitis is a phlebitis (inflammation of a vein) related to a thrombus (blood clot). When it occurs repeatedly in different locations, it is known as thrombophlebitis migrans (migratory thrombophlebitis). Signs and symptoms The following ...
, hematogenous dissemination to distant organs, and coagulation abnormalities.


References

{{reflist, 2 Diseases of oral cavity, salivary glands and jaws Dentistry