Oasis Of Hope Hospital
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The Oasis of Hope Hospital is a clinic in
Tijuana, Mexico Tijuana is the most populous city of the Mexican state of Baja California, located on the northwestern Pacific Coast of Mexico. Tijuana is the municipal seat of the Tijuana Municipality, the hub of the Tijuana metropolitan area and the most popu ...
providing
alternative cancer treatments Alternative cancer treatment describes any cancer treatment or practice that is not part of the conventional standard of cancer care. These include special diets and exercises, chemicals, herbs, devices, and manual procedures. Most alternative ...
to its customers. The clinic was founded by the physician Ernesto Contreras. After his death in 2003, the management of the hospital was taken over by his son, Francisco Contreras, and nephew, Daniel Kennedy. Since the 1960s, it has administered
amygdalin Amygdalin (from Ancient Greek: ' 'almond') is a naturally occurring chemical compound found in many plants, most notably in the seeds (kernels, pips or stones) of apricots, bitter almonds, apples, peaches, cherries and plums, and in the roots ...
to its patients. The clinic has been characterized by
Quackwatch Quackwatch is a United States-based website focused on promoting consumer protection and providing information about health related frauds, myths, fads, fallacies, and misconduct. It primarily targets alternative medicine, questionable health cl ...
as "dubious.”


History

The Oasis of Hope hospital is based in
Tijuana Tijuana is the most populous city of the Mexican state of Baja California, located on the northwestern Pacific Coast of Mexico. Tijuana is the municipal seat of the Tijuana Municipality, the hub of the Tijuana metropolitan area and the most popu ...
,
Mexico Mexico, officially the United Mexican States, is a country in North America. It is the northernmost country in Latin America, and borders the United States to the north, and Guatemala and Belize to the southeast; while having maritime boundar ...
. The city is significant as there is a concentration of more than 60
cancer Cancer is a group of diseases involving Cell growth#Disorders, abnormal cell growth with the potential to Invasion (cancer), invade or Metastasis, spread to other parts of the body. These contrast with benign tumors, which do not spread. Po ...
treatment centres in the city, making it one of the largest concentrations of this type of treatment in the world.
The Guardian ''The Guardian'' is a British daily newspaper. It was founded in Manchester in 1821 as ''The Manchester Guardian'' and changed its name in 1959, followed by a move to London. Along with its sister paper, ''The Guardian Weekly'', ''The Guardi ...
reported in 2005 that the reason for the concentration is that most methods used by the hospitals are ''"discouraged by conventional medical science"'' and because health regulations aren't as strict as the
United States The United States of America (USA), also known as the United States (U.S.) or America, is a country primarily located in North America. It is a federal republic of 50 U.S. state, states and a federal capital district, Washington, D.C. The 48 ...
, it is a logical place for them to operate.
Tijuana Tijuana is the most populous city of the Mexican state of Baja California, located on the northwestern Pacific Coast of Mexico. Tijuana is the municipal seat of the Tijuana Municipality, the hub of the Tijuana metropolitan area and the most popu ...
is home to the largest concentration of cancer treatment centres offering unorthodox therapies anywhere in the world. More than 60 hospitals, clinics and semi-clandestine offices offer to cure or help control the disease in ways ranging from the unconventional to the controversial. Most methods are discouraged by conventional medical science, which is why they are based in
Tijuana Tijuana is the most populous city of the Mexican state of Baja California, located on the northwestern Pacific Coast of Mexico. Tijuana is the municipal seat of the Tijuana Municipality, the hub of the Tijuana metropolitan area and the most popu ...
, where health regulators rarely bother them. After Ernesto's death in 2003, running of the clinic passed to his son Francisco Contreras and Daniel Kennedy, who is Francisco's nephew. In 2005 Ralph Moss, an advocate of alternative cancer treatments, published an article giving something of the clinic's history. He wrote that it was formerly known as the ''Del Mar Medical Center and Hospital'' and was run by Ernesto Contreras who oversaw its expansion to accommodate customers from the
United States The United States of America (USA), also known as the United States (U.S.) or America, is a country primarily located in North America. It is a federal republic of 50 U.S. state, states and a federal capital district, Washington, D.C. The 48 ...
; new English-speaking staff had been hired especially to cater for this client base. According to Moss, despite the fact that the
American Cancer Society The American Cancer Society (ACS) is a nationwide non-profit organization dedicated to eliminating cancer. The ACS publishes the journals ''Cancer'', '' CA: A Cancer Journal for Clinicians'' and '' Cancer Cytopathology''. History The society w ...
had put Ernesto Contreras on a list of practitioners of "unproven methods" in 1971, the clinic claimed to have had 40,000 American customers in the 40 years prior to 2005. In 2014, senior management from The Oasis of Hope hospital visited the
United Kingdom The United Kingdom of Great Britain and Northern Ireland, commonly known as the United Kingdom (UK) or Britain, is a country in Northwestern Europe, off the coast of European mainland, the continental mainland. It comprises England, Scotlan ...
to speak about alternative medicine. At the time they were not allowed to publicly advertise
alternative cancer treatment Alternative cancer treatment describes any cancer treatment or practice that is not part of the conventional standard of cancer care. These include special diets and exercises, chemicals, herbs, devices, and manual procedures. Most alternative ...
s in the
United Kingdom The United Kingdom of Great Britain and Northern Ireland, commonly known as the United Kingdom (UK) or Britain, is a country in Northwestern Europe, off the coast of European mainland, the continental mainland. It comprises England, Scotlan ...
, so the talk was aimed at raising understanding. It was reported however that many of the attendees had
cancer Cancer is a group of diseases involving Cell growth#Disorders, abnormal cell growth with the potential to Invasion (cancer), invade or Metastasis, spread to other parts of the body. These contrast with benign tumors, which do not spread. Po ...
and were considering alternative options. This was following a number of public discussions in the country about how to approach alternative treatments.
Prince Charles Charles III (Charles Philip Arthur George; born 14 November 1948) is King of the United Kingdom and the 14 other Commonwealth realms. Charles was born at Buckingham Palace during the reign of his maternal grandfather, King George VI, and ...
had suggested that the country should itself pursue alternative treatments and offer them in some way. Members of staff from Oasis of Hope visited the UK around the time the Medical Innovation Bill was being discussed. If the bill had passed, it would have opened the door for Oasis of Hope-like treatments to take place in
Britain Britain most often refers to: * Great Britain, a large island comprising the countries of England, Scotland and Wales * The United Kingdom of Great Britain and Northern Ireland, a sovereign state in Europe comprising Great Britain and the north-eas ...
.


Treatment

The Oasis of Hope Hospital offers a variety of alternative cancer treatments. During an interview,
Edzard Ernst Edzard Ernst (born 30 January 1948) is a retired British-German academic physician and researcher specializing in the study of complementary and alternative medicine. He was Professor of Complementary Medicine at the University of Exeter, the wo ...
spoke about the sort of treatments commonly used by hospitals and treatment centers such as the Oasis of Hope. Many of the therapies focus on the removal of
carcinogenic A carcinogen () is any agent that promotes the development of cancer. Carcinogens can include synthetic chemicals, naturally occurring substances, physical agents such as ionizing and non-ionizing radiation, and Biological agent, biologic agent ...
substances. Claims are made by the hospitals that the removal of such substances is able to boost the immune system to then fight off cancer. This treatment is however unproven in traditional medicine. Since the 1960s, Oasis of Hope has treated its patients with
amygdalin Amygdalin (from Ancient Greek: ' 'almond') is a naturally occurring chemical compound found in many plants, most notably in the seeds (kernels, pips or stones) of apricots, bitter almonds, apples, peaches, cherries and plums, and in the roots ...
, also known as
laetrile Amygdalin (from Ancient Greek: ' 'almond') is a naturally occurring chemical compound found in many plants, most notably in the seeds (kernels, pips or stones) of apricots, bitter almonds, apples, peaches, cherries and plums, and in the roots ...
, an ineffective and dangerously toxic substance. By 1978, more than 70,000 people in the United States had reportedly been treated with
Laetrile Amygdalin (from Ancient Greek: ' 'almond') is a naturally occurring chemical compound found in many plants, most notably in the seeds (kernels, pips or stones) of apricots, bitter almonds, apples, peaches, cherries and plums, and in the roots ...
. Between 1996 and 1997, sociologist David Hess conducted an interview with Francisco Contreras, in which he discussed many aspects of the Clinic's operations. Contreras said that metabolic therapy was the main offering of the clinic, and was made up of four steps;
Detoxification Detoxification or detoxication (detox for short) is the physiological or medicinal removal of toxic substances from a living organism, including the human body, which is mainly carried out by the liver. Additionally, it can refer to the period o ...
, restrictive low-fat, low-protein, high-carbohydrate diet, the use of
megavitamin therapy Megavitamin therapy is the use of large doses of vitamins, often many times greater than the recommended dietary allowance (RDA) in the attempt to prevent or treat diseases. Megavitamin therapy is typically used in alternative medicine by pract ...
,
shark cartilage Shark cartilage is a dietary supplement made from the dried and powdered cartilage of a shark; that is, from the tough material that composes a shark's skeleton. Shark cartilage is marketed under a variety of brand names, including Carticin, Cart ...
, thymus and
levamisole Levamisole, sold under the brand name Ergamisol among others, is a medication used to treat parasitic worm infections, specifically ascariasis and hookworm infections. It is taken by mouth. Side effects may include abdominal pain, vomiting, ...
and the use of
amygdalin Amygdalin (from Ancient Greek: ' 'almond') is a naturally occurring chemical compound found in many plants, most notably in the seeds (kernels, pips or stones) of apricots, bitter almonds, apples, peaches, cherries and plums, and in the roots ...
extracted from apricot seeds. Another therapy was called the "Warburg" therapy named (according to Hess's account) after
Otto Heinrich Warburg Otto Heinrich Warburg (, ; 8 October 1883 – 1 August 1970) was a German physiologist, medical doctor, and Nobel laureate. He served as an officer in the elite Uhlan (cavalry regiment) during the First World War, and was awarded the Iron Cross ...
. This consisted of a restrictive high-carbohydrate diet, giving patients
insulin Insulin (, from Latin ''insula'', 'island') is a peptide hormone produced by beta cells of the pancreatic islets encoded in humans by the insulin (''INS)'' gene. It is the main Anabolism, anabolic hormone of the body. It regulates the metabol ...
and
quercetin Quercetin is a plant flavonol from the flavonoid group of polyphenols. It is found in many fruits, vegetables, leaves, seeds, and grains; capers, red onions, and kale are common foods containing appreciable amounts of it. It has a bitter flavor ...
. Hess also wrote that Contreras cited a number of non-physical aspects to the clinic's therapy, including religious assistance, psychology and singing and laughter sessions – Contreras claimed that people with strong spiritual beliefs recovered better, and that laughter stimulates the immune system. In 2005 Ralph Moss reported that the clinic was using amygdalin and the Issels treatment. In 2011 Moss wrote a further report on the Tijuana clinics, and noted that their ability to attract customers had been diminished by the publication of research showing that amygdalin was not effective, by tougher regulation arising from the 1994
North American Free Trade Agreement The North American Free Trade Agreement (, TLCAN; , ALÉNA), referred to colloquially in the Anglosphere as NAFTA, ( ) was an agreement signed by Canada, Mexico, and the United States that created a trilateral trade bloc in North America. The ...
, and from Tijuana itself become a less desirable destination as a result of a decline brought on by the war on drugs. Moss also noted that some American hospitals now have alternative medicine offerings, diminishing the distinctive appeal of the clinics in Tijuana. In 2005, ''
The Guardian ''The Guardian'' is a British daily newspaper. It was founded in Manchester in 1821 as ''The Manchester Guardian'' and changed its name in 1959, followed by a move to London. Along with its sister paper, ''The Guardian Weekly'', ''The Guardi ...
'' reported the case of a man with cancer who paid US$40,000 for a one-month treatment in which he had high-fevers induced in the belief that the heat would kill his cancer cells.


Evidence

Amygdalin Amygdalin (from Ancient Greek: ' 'almond') is a naturally occurring chemical compound found in many plants, most notably in the seeds (kernels, pips or stones) of apricots, bitter almonds, apples, peaches, cherries and plums, and in the roots ...
(sometimes called "laetrile") is a toxic
glycoside In chemistry, a glycoside is a molecule in which a sugar is bound to another functional group via a glycosidic bond. Glycosides play numerous important roles in living organisms. Many plants store chemicals in the form of inactive glycosides. ...
. The major argument against the use of amygdalin is that it is a toxic glycoside, which has been known to provoke
cyanide poisoning Cyanide poisoning is poisoning that results from exposure to any of a number of forms of cyanide. Early symptoms include headache, dizziness, fast heart rate, shortness of breath, and vomiting. This phase may then be followed by seizures, slo ...
in patients. Evidence that is frequently used to display this is people that suffered cyanide poisoning after ingesting bitter
almonds The almond (''Prunus amygdalus'', syn. ''Prunus dulcis'') is a species of tree from the genus ''Prunus''. Along with the peach, it is classified in the subgenus ''Amygdalus'', distinguished from the other subgenera by corrugations on the sh ...
, which contain amygdalin. Issels treatment requires removal of metal fillings from the patient's mouth and adherence to a restrictive diet, supposedly to aid in cancer treatment.
Cancer Research UK Cancer Research UK (CRUK) is the world's largest independent cancer research organisation. It is registered as a charity in the United Kingdom and Isle of Man, and was formed on 4 February 2002 by the merger of The Cancer Research Campaign and t ...
have said of it: "There is no scientific or medical evidence to back up the claims made by the Issels website".


Reception

Edzard Ernst Edzard Ernst (born 30 January 1948) is a retired British-German academic physician and researcher specializing in the study of complementary and alternative medicine. He was Professor of Complementary Medicine at the University of Exeter, the wo ...
, a former professor at
The University of Exeter The University of Exeter is a research university in the West Country of England, with its main campus in Exeter, Devon. Its predecessor institutions, St Luke's College, Exeter School of Science, Exeter School of Art, and the Camborne School of ...
stated that Britons in particular were attracted to
Tijuana Tijuana is the most populous city of the Mexican state of Baja California, located on the northwestern Pacific Coast of Mexico. Tijuana is the municipal seat of the Tijuana Municipality, the hub of the Tijuana metropolitan area and the most popu ...
clinics ''"because the clinics there are famous."'' According to Quackwatch, the Oasis of Hope Hospital is a "dubious cancer clinic". Richard Sullivan of Cancer Research UK has said, "the Tijuana clinics are essentially set up to deceive and it's a disgrace." Barrie R. Cassileth commented on a small longterm follow-up study that had been carried out on patients of Mexican clinics, including those taking the Contreras treatments. She said that most patients did not know what stage their cancer was at, but that the mean survival time – of 7 months – was enough to conclude that "Contreras therapy is ineffective in treating late-stage cancer patients". The
Memorial Sloan-Kettering Cancer Center Memorial Sloan Kettering Cancer Center (MSK or MSKCC) is a oncology, cancer treatment and research institution in Manhattan in New York City. MSKCC is one of 72 National Cancer Institute–NCI-designated Cancer Center, designated Comprehen ...
lists "Contreras Therapy" alongside other alternative nutrition-based cancer treatments like the
Gerson Therapy Max Gerson (October 18, 1881 – March 8, 1959) was a German-born American physician who developed the Gerson therapy, a pseudoscientific dietary-based alternative cancer treatment that he falsely claimed could cure cancer and most chronic, ...
which "show no evidence of efficacy".


See also

*
List of ineffective cancer treatments A list is a set of discrete items of information collected and set forth in some format for utility, entertainment, or other purposes. A list may be memorialized in any number of ways, including existing only in the mind of the list-maker, but ...
*
Quackery Quackery, often synonymous with health fraud, is the promotion of fraudulent or Ignorance, ignorant medicine, medical practices. A quack is a "fraudulent or ignorant pretender to medical skill" or "a person who pretends, professionally or public ...
*
Clinica 0-19 Clinica 0-19 is a medical clinic in Monterrey, Mexico that claims to treat diffuse intrinsic pontine glioma (DIPG). Although DIPG is currently regarded as one of the most devastating pediatric cancers, with a survival rate of <1% over five years, t ...


References


Further reading

* *{{cite journal, doi=10.3322/canjclin.21.5.317, title=Unproven methods of cancer management: Contreras Methods, year=1971, journal=CA: A Cancer Journal for Clinicians, volume=21, issue=5, pages=317–321, pmid=4999535 , doi-access=free


External links


Official clinic web site
Alternative cancer treatments Pseudoscience Medical and health organizations based in Mexico