Noribogaminalog, or ''N''-desmethylibogaminalog, also known as 1,2,3,4,5,6-hexahydroazepino ,5-bndole, is a

chemical compound A chemical compound is a chemical substance composed of many identical molecules (or molecular entities) containing atoms from more than one chemical element held together by chemical bonds. A molecule consisting of atoms of only one element ...

and

parent structure In chemistry, a parent structure is the structure of an unadorned ion or molecule from which derivatives can be visualized. Parent structures underpin systematic nomenclature and facilitate classification. Fundamental parent structures have on ...

of the ibogalog group of compounds. The ibogalogs that have been described include

ibogaminalog Ibogaminalog (developmental code name DM-506) is a drug of the ibogalog group first invented in the 1960s, which acts as both a partial agonist at the 5-HT2A receptor, 5-HT2A Receptor (biochemistry), receptor, and a negative allosteric modulator ...

ibogainalog Ibogainalog (IBG), also known as 9-methoxyibogaminalog, is a serotonergic psychedelic and psychoplastogen of the ibogalog group related to ibogaine but with a simplified chemical structure. Pharmacology It acts as a serotonin 5-HT2A receptor a ...

, noribogainalog,

tabernanthalog Tabernanthalog (TBG, DLX-007) is a novel water-soluble, non-toxic ibogalog or simplified analogue of the psychoactive drug tabernanthine first synthesized by David E. Olson at UC Davis. Tabernanthalog is a non-hallucinogenic serotonin 5-HT2A ...

, fluorogainalog, LS-22925,

PNU-22394 PNU-22394 is a drug of the ibogalog group which acts as an agonist at serotonin 5-HT2 Receptor (biochemistry), receptors, with strongest binding affinity for 5-HT2A receptor, 5-HT2A and 5-HT2C receptor, 5-HT2C and slightly weaker at 5-HT2B recept ...

, and

PHA-57378 PHA-57378 is a drug related to the ibogalogs which acts as an agonist at serotonin 5-HT2 receptors, having a binding affinity of 4.1 nM at the 5-HT2A subtype and 4.3 nM at 5-HT2C. It has anxiolytic effects in animal studies. See also * Ibog ...

, among others. The ibogalogs, specifically ibogainalog and analogues, were first described in the

scientific literature Scientific literature encompasses a vast body of academic papers that spans various disciplines within the natural and social sciences. It primarily consists of academic papers that present original empirical research and theoretical ...

by 1968.

References

External links

Noribogaminalog - Isomer Design

Ibogalogs, Drug Discovery, and the New Psychedelic Era - NeuWrite West
Ibogalogs {{Organic-compound-stub