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Niflumic acid is a drug used for joint and muscular pain. It is categorized as an inhibitor of cyclooxygenase-2. In experimental biology, it has been employed to inhibit
chloride channel Chloride channels are a superfamily of poorly understood ion channels specific for chloride. These channels may conduct many different ions, but are named for chloride because its concentration ''in vivo'' is much higher than other anions. Several ...
s. It has also been reported to act on GABA-A and NMDA channels and to block T-type calcium channels.


References

Disubstituted pyridines Anilines Trifluoromethyl compounds Calcium channel blockers GABAA receptor positive allosteric modulators NMDA receptor antagonists Aromatic acids Chloride channel blockers Alpha-Amino acids {{musculoskeletal-drug-stub