Niflumic acid is a drug used for joint and muscular pain. It is categorized as an inhibitor of
cyclooxygenase-2. In experimental biology, it has been employed to inhibit
chloride channel
Chloride channels are a superfamily of poorly understood ion channels specific for chloride. These channels may conduct many different ions, but are named for chloride because its concentration ''in vivo'' is much higher than other anions. Several ...
s. It has also been reported to act on GABA-A and
NMDA channels and to block T-type calcium channels.
References
Disubstituted pyridines
Anilines
Trifluoromethyl compounds
Calcium channel blockers
GABAA receptor positive allosteric modulators
NMDA receptor antagonists
Aromatic acids
Chloride channel blockers
Alpha-Amino acids
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