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''Neocosmospora'' is a
genus Genus ( plural genera ) is a taxonomic rank used in the biological classification of living and fossil organisms as well as viruses. In the hierarchy of biological classification, genus comes above species and below family. In binomial n ...
of
fungi A fungus (plural, : fungi or funguses) is any member of the group of Eukaryote, eukaryotic organisms that includes microorganisms such as yeasts and Mold (fungus), molds, as well as the more familiar mushrooms. These organisms are classified ...
in the family
Nectriaceae The Nectriaceae comprise a family of fungi in the order Hypocreales. It was circumscribed by brothers Charles and Louis René Tulasne in 1865. List of genera This is an incomplete list of genera Genus ( plural genera ) is a taxonomic rank ...
. The genus was established by Smith in 1899. Species in the genus are
saprobes Saprotrophic nutrition or lysotrophic nutrition is a process of chemoheterotrophic extracellular digestion involved in the processing of decayed (dead or waste) organic matter. It occurs in saprotrophs, and is most often associated with fungi ( ...
(processing of decayed (dead or waste) organic matter),
endophytes An endophyte is an endosymbiont, often a bacterium or fungus, that lives within a plant for at least part of its life cycle without causing apparent disease. Endophytes are ubiquitous and have been found in all species of plants studied to date; h ...
(a fungus that lives within a plant for at least part of its life cycle), and plant and animal pathogens and they are commonly found in soil, plant debris, living plant material, air and water (Sandoval-Denis et al. 2019; Guarnaccia et al. 2021).


Species

As accepted by
Species Fungorum ''Index Fungorum'' is an international project to index all formal names ( scientific names) in the fungus kingdom. the project is based at the Royal Botanic Gardens, Kew, one of three partners along with Landcare Research and the Institute of ...
; *'' Neocosmospora arxii'' *'' Neocosmospora boninensis'' *'' Neocosmospora endophytica'' *'' Neocosmospora floridana'' *'' Neocosmospora indica'' *''
Neocosmospora kurunegalensis ''Neocosmospora'' is a genus of fungi in the family Nectriaceae. The genus was established by Smith in 1899. Species in the genus are saprobes (processing of decayed (dead or waste) organic matter), endophytes (a fungus that lives within a plant ...
'' *'' Neocosmospora leucaenae'' *''
Neocosmospora magnoliae ''Neocosmospora'' is a genus of fungi in the family Nectriaceae. The genus was established by Smith in 1899. Species in the genus are saprobes (processing of decayed (dead or waste) organic matter), endophytes (a fungus that lives within a pl ...
'' *''
Neocosmospora obliquiseptata ''Neocosmospora'' is a genus of fungi in the family Nectriaceae. The genus was established by Smith in 1899. Species in the genus are saprobes (processing of decayed (dead or waste) organic matter), endophytes (a fungus that lives within a plant ...
'' *''
Neocosmospora parva ''Neocosmospora'' is a genus of Fungus, fungi in the family Nectriaceae. The genus was established by Smith in 1899. Species in the genus are saprobes (processing of decayed (dead or waste) organic matter), endophytes (a fungus that lives within ...
'' *''
Neocosmospora rekana ''Neocosmospora'' is a genus of fungi in the family Nectriaceae. The genus was established by Smith in 1899. Species in the genus are saprobes (processing of decayed (dead or waste) organic matter), endophytes (a fungus that lives within a pl ...
'' *''
Neocosmospora rubicola ''Neocosmospora'' is a genus of fungi in the family Nectriaceae. The genus was established by Smith in 1899. Species in the genus are saprobes (processing of decayed (dead or waste) organic matter), endophytes (a fungus that lives within a pl ...
'' *''
Neocosmospora striata ''Neocosmospora'' is a genus of fungi in the family Nectriaceae. The genus was established by Smith in 1899. Species in the genus are saprobes (processing of decayed (dead or waste) organic matter), endophytes (a fungus that lives within a pl ...
'' *''
Neocosmospora striatispora ''Neocosmospora'' is a genus of fungi in the family Nectriaceae. The genus was established by Smith in 1899. Species in the genus are saprobes (processing of decayed (dead or waste) organic matter), endophytes (a fungus that lives within a pl ...
'' *''
Neocosmospora thailandica ''Neocosmospora'' is a genus of fungi in the family Nectriaceae. The genus was established by Smith in 1899. Species in the genus are saprobes (processing of decayed (dead or waste) organic matter), endophytes (a fungus that lives within a pl ...
'' *''
Neocosmospora tuaranensis ''Neocosmospora'' is a genus of fungi in the family Nectriaceae. The genus was established by Smith in 1899. Species in the genus are saprobes (processing of decayed (dead or waste) organic matter), endophytes (a fungus that lives within a pl ...
''


Uses of Neocosmospora species

Bioassay-guided
fractionation Fractionation is a separation process in which a certain quantity of a mixture (of gases, solids, liquids, enzymes, or isotopes, or a suspension) is divided during a phase transition, into a number of smaller quantities (fractions) in whic ...
of a fungus ''Neocosmospora'' sp. resulted in the isolation of three new
resorcylic acid lactone Resorcylic acid lactones are a group of estrogenic compounds. They are lactones of resorcylic acid. Examples include the mycoestrogens (and synthetic analogues) zearalenone, zearalanone, zeranol (α-zearalanol), taleranol Taleranol (INN, ...
s, 'neocosmosin A' (2), 'neocosmosin B' (3) and 'neocosmosin C' (4). As well as three known resorcylic acid lactones, 'monocillin IV' (1), 'monocillin II' (5) and
radicicol Radicicol, also known as monorden, is a natural product that binds to Hsp90 (Heat Shock Protein 90) and alters its function. HSP90 client proteins play important roles in the regulation of the cell cycle, cell growth, cell survival, apoptosis, a ...
(6) which were also isolated and identified, where compounds 4–6 show good binding affinity for the human
opioid receptor Opioid receptors are a group of inhibitory G protein-coupled receptors with opioids as ligands. The endogenous opioids are dynorphins, enkephalins, endorphins, endomorphins and nociceptin. The opioid receptors are ~40% identical to somatosta ...
s. These findings have important implications for the potential psychoactive effects with this class of compounds.


References


External links

* Nectriaceae genera {{Hypocreales-stub