The National Center for Advancing Translational Sciences (NCATS) was established on December 23, 2011 and is located in

Bethesda, Maryland Bethesda () is an unincorporated, census-designated place in southern Montgomery County, Maryland, United States. Located just northwest of Washington, D.C., it is a major business and government center of the Washington metropolitan region ...

. NCATS is one of 27 institutes and centers of the U.S.

National Institutes of Health The National Institutes of Health (NIH) is the primary agency of the United States government responsible for biomedical and public health research. It was founded in 1887 and is part of the United States Department of Health and Human Service ...

(NIH), an agency of the

U.S. Department of Health and Human Services The United States Department of Health and Human Services (HHS) is a cabinet-level executive branch department of the US federal government created to protect the health of the US people and providing essential human services. Its motto is "Im ...

. The mission of NCATS is to transform scientific discoveries into new treatments and cures for disease that can be delivered faster to patients. The budget provided to NCATS for fiscal year 2018 is $557,373,000.

History

NCATS was created on December 23, 2011 by the Consolidated Appropriations Act, 2012. The center was created from a number of existing NIH programs: *

Clinical and Translational Science Award Clinical and Translational Science Award (CTSA) is a type of U.S. federal grant administered by the National Center for Advancing Translational Sciences, part of the National Institutes of Health. The CTSA program began in October 2006 under the au ...

program * Components of the Molecular Libraries Program * Therapeutics for Rare and Neglected Diseases * RAID renamed Bridging Interventional Development Gaps * Office of Rare Diseases Research * NIH–FDA Regulatory Science Initiative * Cures Acceleration Network (CAN)

Directors

Past directors 2011 – present

Divisions

NCATS is organized into a number of divisions: * Division of Clinical Innovation * Division of Pre-Clinical Innovation * Office of Administrative Management * Office of Grants Management and Scientific Review * Office of Rare Diseases Research: Oversees the Rare Diseases Clinical Research Network and Genetic and Rare Diseases Information Center (GARD) * Office of Strategic Alliances: Works with businesses in the biotech and pharmaceutical industry to speed the development of new drugs

Programs and initiatives

Overview

The stated goal of NCATS is to promote research in both existing and new areas of medicine and science, in order to promote public health and to overcome high failure rates in clinical trials. To accomplish this, NCATS supports 31 programs and initiatives that relate to translational research and improving the speed of therapeutic development. The 31 programs and initiatives involve a range of STEM-related fields including biology, biochemistry, chemistry, bioengineering, virology, genetics, and data science. Within the realm of translational science, issues that NCATS is particularly focused on addressing using its programs, initiatives, and partnerships include increasing the success and de-risking the costs associated with therapeutic development, incentivizing more collaborative work, and addressing data transparency issues.

COVID response

During the COVID-19 pandemic, NCATS launched an open data initiative to promote collaborative sharing of COVID-related drug data. An additional data sharing partnership with several other government institutes resulted in a study detailing the COVID-related risks for patients with chronic obstructive pulmonary disease.

References

{{coord missing, Maryland National Institutes of Health Medical research institutes in Maryland