A narrow-
spectrum
A spectrum (: spectra or spectrums) is a set of related ideas, objects, or properties whose features overlap such that they blend to form a continuum. The word ''spectrum'' was first used scientifically in optics to describe the rainbow of co ...
antibiotic is an
antibiotic
An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting pathogenic bacteria, bacterial infections, and antibiotic medications are widely used in the therapy ...
that is only able to kill or inhibit limited species of bacteria.
Examples of narrow-spectrum antibiotics include
fidaxomicin and
sarecycline
Sarecycline, sold under the brand name Seysara, is a narrow-spectrum tetracycline-derived antibiotic medication. It is specifically designed for the treatment of acne, and was approved by the FDA in October 2018 for the treatment of inflammat ...
.
Advantages
* Narrow-spectrum antibiotic allow to kill or inhibit only those bacteria species that are unwanted (i.e. causing disease). As such, it leaves most of the beneficial bacteria unaffected, hence minimizing the collateral damage on the
microbiota.
* Low propensity for
bacterial resistance development.
Disadvantages
Often, the exact species of bacteria causing the illness is unknown, in which case narrow-spectrum antibiotics can't be used, and broad-spectrum antibiotics are used instead. To know the exact species of bacteria causing the illness, clinical specimens need to be taken for antimicrobial susceptibility testing in a
clinical microbiology laboratory.
See also
*
Antimicrobial spectrum
*
Broad-spectrum antibiotics
References
Further reading
Repurposing CRISPR-Cas systems as DNA-based smart antimicrobials
{{antibiotic-stub
Antibiotics