Nucleoporin 188 (Nup188) is a protein that in humans is encoded by the ''NUP188''

gene In biology, the word gene has two meanings. The Mendelian gene is a basic unit of heredity. The molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protei ...

Function

Transport of macromolecules between the cytoplasm and nucleus occurs through

nuclear pore The nuclear pore complex (NPC), is a large protein complex giving rise to the nuclear pore. A great number of nuclear pores are studded throughout the nuclear envelope that surrounds the eukaryote cell nucleus. The pores enable the nuclear tran ...

complexes (NPCs) embedded in the

nuclear envelope The nuclear envelope, also known as the nuclear membrane, is made up of two lipid bilayer membranes that in eukaryotic cells surround the nucleus, which encloses the genetic material. The nuclear envelope consists of two lipid bilayer membran ...

. NPCs are composed of subcomplexes, and NUP188 is part of one such subcomplex.

References

External links

* Nuclear pore complex {{gene-9-stub