''Mycolicibacillus'' is a genus of

Gram-Positive In bacteriology, gram-positive bacteria are bacteria that give a positive result in the Gram stain test, which is traditionally used to quickly classify bacteria into two broad categories according to their type of cell wall. The Gram stain is ...

rod-shaped bacteria Bacterial cellular morphologies are the shapes that are characteristic of various types of bacteria and often key to their identification. Their direct examination under a light microscope enables the classification of these bacteria (and archaea ...

in the family ''Mycobacteriaceae'' from the order

Mycobacteriales The Mycobacteriales are an order of bacteria. The current description is genome-based, per Gupta 2019 emendation. Most members produce mycolic acids. Phylogeny The currently accepted taxonomy is based on the List of Prokaryotic names with Standi ...

. Members of ''Mycolicibacillus'' were demarcated from the larger genus ''

Mycobacterium ''Mycobacterium'' is a genus of over 190 species in the phylum Actinomycetota, assigned its own family, Mycobacteriaceae. This genus includes pathogens known to cause serious diseases in mammals, including tuberculosis (''Mycobacterium tuberculo ...

'' in 2018 by Gupta et al. based on evidence from various phylogenetic trees constructed based on conserved genome sequences, comparative genomic analyses and average amino acid identity values. In addition to this genus, the study proposed the division of ''Mycobacterium'' into a total of five distinct genera, which was met with some resistance by some of the scientific community. The resistance was based on the grounds that ''Mycobacterium'' contains some clinically relevant species and name changes might cause confusion among clinicians and other researchers. In 2020, Yamada et al. analyzed the fundamental morphological properties of the new genera, including the cell diameter, cell length, cell perimeter, cell circularity and aspect ratio, and determined that there were significant differences between the five genera, thus supporting the new division. The name ''Mycolicibacillus'' is derived from the Latin noun ''acidum mycolicum'' (translates to mycolic acid) and the Latin noun ''bacillus'' (translates to small staff or rod). Together the name refers to a genus of mycolic acid-containing, rod-shaped bacteria.

Biochemical characteristics and molecular signatures

While majority of the genus are slow growing bacteria species (taking more than seven days to form colonies), some do display intermediate growth rates (taking 5–15 days to form colonies). All species are nonchromogenic. Species are not thought to be pathogenic, although some have been isolated form human patients with pulmonary dysfunction. The genome size for the members of ''Mycolicibacillus'' ranges from 3.89–4.08 Mbp and their

G+C content G, or g, is the seventh letter of the Latin alphabet, used in the modern English alphabet, the alphabets of other western European languages, and others worldwide. Its name in English is ''gee'' (pronounced ), plural ''gees''. The lower ...

is 69.4

mol% In chemistry, the mole fraction or molar fraction, also called mole proportion or molar proportion, is a quantity defined as the ratio between the amount of a constituent substance, ''ni'' (expressed in unit of moles, symbol mol), and the tota ...

. 22 unique conserved signature proteins (CSPs) were identified for this genus.

Phylogeny

The phylogeny of ''Mycolicibacillus'' is based on

16S rRNA 16S ribosomal RNA (or 16Svedberg, S rRNA) is the RNA component of the 30S subunit of a prokaryotic ribosome (SSU rRNA). It binds to the Shine-Dalgarno sequence and provides most of the SSU structure. The genes coding for it are referred to as ...

analysis.

References

{{Taxonbar, from=Q107335051 Mycobacteriales Bacteria genera