''Mycobacterium farcinogenes'' is a species of the phylum

Actinomycetota The ''Actinomycetota'' (or ''Actinobacteria'') are a phylum of all gram-positive bacteria. They can be terrestrial or aquatic. They are of great economic importance to humans because agriculture and forests depend on their contributions to soi ...

(

Gram-positive In bacteriology, gram-positive bacteria are bacteria that give a positive result in the Gram stain test, which is traditionally used to quickly classify bacteria into two broad categories according to their type of cell wall. Gram-positive bac ...

bacteria Bacteria (; singular: bacterium) are ubiquitous, mostly free-living organisms often consisting of one biological cell. They constitute a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria were am ...

with high guanine and cytosine content, one of the dominant phyla of all bacteria), belonging to the genus ''

Mycobacterium ''Mycobacterium'' is a genus of over 190 species in the phylum Actinomycetota, assigned its own family, Mycobacteriaceae. This genus includes pathogens known to cause serious diseases in mammals, including tuberculosis (''M. tuberculosis'') and l ...

''. Although slow-growing, it is similar to fast-growing species, and is usually classified with them.

Description

, nonmotile and strongly acid-fast rods. Short or long filaments, bent and branched, in clumps or tangled, lacy network. Colony characteristics Rough, yellow and convoluted

colonies In modern parlance, a colony is a territory subject to a form of foreign rule. Though dominated by the foreign colonizers, colonies remain separate from the administration of the original country of the colonizers, the '' metropolitan state' ...

. Firmly adherent to medium and surrounded by an

iridescent Iridescence (also known as goniochromism) is the phenomenon of certain surfaces that appear to gradually change color as the angle of view or the angle of illumination changes. Examples of iridescence include soap bubbles, feathers, butterfl ...

halo. Physiology *Slow growth after 15–20 days on Löwenstein-Jensen medium. Differential characteristics *On the basis of characteristic

lipid Lipids are a broad group of naturally-occurring molecules which includes fats, waxes, sterols, fat-soluble vitamins (such as vitamins A, D, E and K), monoglycerides, diglycerides, phospholipids, and others. The functions of lipids incl ...

s this

species In biology, a species is the basic unit of Taxonomy (biology), classification and a taxonomic rank of an organism, as well as a unit of biodiversity. A species is often defined as the largest group of organisms in which any two individuals of ...

belongs to the genus ''

'' and not to the genus ''

Nocardia ''Nocardia'' is a genus of weakly staining Gram-positive, catalase-positive, rod-shaped bacteria. It forms partially acid-fast beaded branching filaments (acting as fungi, but being truly bacteria). It contains a total of 85 species. Some spec ...

''. *DNA homology to the closely related species '' Mycobacterium senegalense''. Both species, share an identical 5'

16S rDNA 16 S ribosomal RNA (or 16 S rRNA) is the RNA component of the 30S subunit of a prokaryotic ribosome (SSU rRNA). It binds to the Shine-Dalgarno sequence and provides most of the SSU structure. The genes coding for it are referred to as 16S rRN ...

sequence. However, the ITS sequences are different.

Pathogenesis

*Causes farcy in African

cattle Cattle (''Bos taurus'') are large, domesticated, cloven-hooved, herbivores. They are a prominent modern member of the subfamily Bovinae and the most widespread species of the genus '' Bos''. Adult females are referred to as cows and adult ...

. *Distinctive

pathogen In biology, a pathogen ( el, πάθος, "suffering", "passion" and , "producer of") in the oldest and broadest sense, is any organism or agent that can produce disease. A pathogen may also be referred to as an infectious agent, or simply a ger ...

icity for

guinea pig The guinea pig or domestic guinea pig (''Cavia porcellus''), also known as the cavy or domestic cavy (), is a species of rodent belonging to the genus '' Cavia'' in the family Caviidae. Breeders tend to use the word ''cavy'' to describe the ...

s: on subcutaneous inoculation, ''M. farcinogenes'' produces draining and slow healing abscesses after 8 days.

Type strain

*First isolated from lesions of farcy in African

bovines Bovines ( subfamily Bovinae) comprise a diverse group of 10 genera of medium to large-sized ungulates, including cattle, bison, African buffalo, water buffalos, and the four-horned and spiral-horned antelopes. The evolutionary relationship betw ...

(Chad). Strain IEMVT 75 = ATCC 35753 = CCUG 21047 = DSM 43637 = NCTC 10955.

References

External links

Type strain of ''Mycobacterium farcinogenes'' at Bac''Dive'' - the Bacterial Diversity Metadatabase
Acid-fast bacilli farcinogenes Bacteria described in 1973 {{Mycobacterium-stub