Munc-13 (an

acronym An acronym is a type of abbreviation consisting of a phrase whose only pronounced elements are the initial letters or initial sounds of words inside that phrase. Acronyms are often spelled with the initial Letter (alphabet), letter of each wor ...

for mammalian uncoordinated-13) is a protein which complexes with RIM and likely comprises part of cellular structure which anchors

synaptic vesicle In a neuron, synaptic vesicles (or neurotransmitter vesicles) store various neurotransmitters that are exocytosis, released at the chemical synapse, synapse. The release is regulated by a voltage-dependent calcium channel. Vesicle (biology), Ves ...

s. Its activation by DAG seems to be important for maintaining high rate of synaptic release during prolonged repetitive stimulation.

References

Proteins Secretory vesicles Neurophysiology {{Protein-stub