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Multiple cutaneous leiomyomas, also known as Pilar leiomyomas, arise from the
arrectores pilorum The arrector pili muscles, also known as hair erector muscles, are small muscles attached to hair follicles in mammals. Contraction of these muscles causes the hairs to stand on end, known colloquially as goose bumps (piloerection). Structure ...
muscles, and are made up of a poorly circumscribed proliferation of haphazardly arranged
smooth muscle Smooth muscle is an involuntary non- striated muscle, so-called because it has no sarcomeres and therefore no striations (''bands'' or ''stripes''). It is divided into two subgroups, single-unit and multiunit smooth muscle. Within single-unit ...
fibers located in the dermis that appear to infiltrate the surrounding tissue and may extend into the subcutis.Freedberg, et al. (2003). ''Fitzpatrick's Dermatology in General Medicine''. (6th ed.). Page 1033. McGraw-Hill. . Sometimes associated with uterine leiomyomas (a combination known as
multiple cutaneous and uterine leiomyomatosis Multiple may refer to: Economics * Multiple finance, a method used to analyze stock prices *Multiples of the price-to-earnings ratio * Chain stores, are also referred to as 'Multiples' *Box office multiple, the ratio of a film's total gross to t ...
, MCUL), these lesions may also be a manifestation of the
hereditary leiomyomatosis and renal cell cancer Reed's syndrome is a rare inherited condition characterised by multiple cutaneous leiomyomas and, in women, uterine leiomyomas. It predisposes for renal cell cancer, an association denominated hereditary leiomyomatosis and renal cell cancer, a ...
syndrome.


See also

*
List of cutaneous conditions Many skin conditions affect the human integumentary system—the organ system covering the entire surface of the body and composed of skin, hair, nails, and related muscle and glands. The major function of this system is as a barrier agai ...


References


External links

Dermal and subcutaneous growths {{Dermal-growth-stub