Mostafa Ronaghi (; born 1968) is an Iranian

molecular biologist Molecular biology is a branch of biology that seeks to understand the molecule, molecular basis of biological activity in and between Cell (biology), cells, including biomolecule, biomolecular synthesis, modification, mechanisms, and interactio ...

, specializing in

DNA sequencing DNA sequencing is the process of determining the nucleic acid sequence – the order of nucleotides in DNA. It includes any method or technology that is used to determine the order of the four bases: adenine, thymine, cytosine, and guanine. The ...

methodology. He earned his Ph.D. from the

Royal Institute of Technology KTH Royal Institute of Technology (), abbreviated KTH, is a public research university in Stockholm, Sweden. KTH conducts research and education in engineering and technology and is Sweden's largest technical university. Since 2018, KTH consist ...

in Sweden in 1998. , he is the Chief Technology Officer and Senior Vice President at Illumina. Prior to this position, he was a principal investigator and Senior Research Associate at the Stanford Genome Technology Center at

Stanford University Leland Stanford Junior University, commonly referred to as Stanford University, is a Private university, private research university in Stanford, California, United States. It was founded in 1885 by railroad magnate Leland Stanford (the eighth ...

, focusing on developing analytical techniques for molecular diagnostics. He is principal investigator for several grants including grants from the

National Human Genome Research Institute The National Human Genome Research Institute (NHGRI) is an institute of the National Institutes of Health, located in Bethesda, Maryland. NHGRI began as the Office of Human Genome Research in The Office of the Director in 1988. This Office transi ...

(NHGRI), part of the

National Institutes of Health The National Institutes of Health (NIH) is the primary agency of the United States government responsible for biomedical and public health research. It was founded in 1887 and is part of the United States Department of Health and Human Service ...

for the development of array-based

Pyrosequencing Pyrosequencing is a method of DNA sequencing (determining the order of nucleotides in DNA) based on the "sequencing by synthesis" principle, in which the sequencing is performed by detecting the nucleotide incorporated by a DNA polymerase. Pyrosequ ...

. In 1998, he described together with Pål Nyren an
Mathias Uhlen
a solution-based variant of the

pyrosequencing Pyrosequencing is a method of DNA sequencing (determining the order of nucleotides in DNA) based on the "sequencing by synthesis" principle, in which the sequencing is performed by detecting the nucleotide incorporated by a DNA polymerase. Pyrosequ ...

technology and co-founded Pyrosequencing AB (renamed to Biotage in 2003). He co-invented Molecular Inversion Probe assay and co-founded ParAllele BioScience to develop this multiplexed technology for genetic testing. ParAllele was acquired by

Affymetrix Affymetrix is now Applied Biosystems, a brand of DNA microarray products sold by Thermo Fisher Scientific that originated with an American biotechnology research and development and manufacturing company of the same name. The Santa Clara, Calif ...

in May 2005. In 2005, he co-founded NextBio, a search engine for life science data that was acquired by Illumina in 2013. He also serves on the board of directors of IntegenX and Aurora Biofuels. In 2008, Ronaghi and Helmy Eltoukhy co-founded Avantome, a DNA sequencing company that was acquired by Illumina in July 2008.tradingmarkets.com , 2008 Release: Illumina To Acquire Privately-Held Avantome For $25 Million In Cash Upfront
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Publications

Among his approximately 50 peer-reviewed journal articles are the publications describing Pyrosequencing and Molecular Inversion Probe assays and other techniques: * * * * * * He also holds about 20 patents.

References

* yrosequencing Array for DNA Sequencing

External links

Stanford Genome Technology Center

NextBio

IntegenX, Inc.

Aurora Biofuels
{{DEFAULTSORT:Ronaghi, Mostafa 1968 births Living people KTH Royal Institute of Technology alumni American people of Iranian descent Iranian biologists Iranian expatriate academics Iranian chief technology officers