Moperone (Luvatren, since discontinued) is a

typical antipsychotic Typical antipsychotics (also known as major tranquilizers, and first generation antipsychotics) are a class of antipsychotic drugs first developed in the 1950s and used to treat psychosis (in particular, schizophrenia). Typical antipsychotics m ...

of the butyrophenone class which is marketed in

Japan Japan is an island country in East Asia. Located in the Pacific Ocean off the northeast coast of the Asia, Asian mainland, it is bordered on the west by the Sea of Japan and extends from the Sea of Okhotsk in the north to the East China Sea ...

for the treatment of

schizophrenia Schizophrenia () is a mental disorder characterized variously by hallucinations (typically, Auditory hallucination#Schizophrenia, hearing voices), delusions, thought disorder, disorganized thinking and behavior, and Reduced affect display, f ...

. It is an

antagonist An antagonist is a character in a story who is presented as the main enemy or rival of the protagonist and is often depicted as a villain.D₂ (''K_i'' 0.7–1.9 nM), D₃ (''K_i'' 0.1–1 nM), and 5-HT_2A (''K_i'' 52 nM) receptors. It also has a high binding affinity for the sigma receptors.

References

Abandoned drugs Tertiary alcohols Butyrophenone antipsychotics 4-Fluorophenyl compounds 4-Phenylpiperidines Typical antipsychotics 4-Tolyl compounds {{nervous-system-drug-stub