Monica Asman
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Sister Monica Asman (September 14, 1920 – April 5, 2016) was an American Catholic nun and research scientist at
University of California, Berkeley The University of California, Berkeley (UC Berkeley, Berkeley, Cal, or California), is a Public university, public Land-grant university, land-grant research university in Berkeley, California, United States. Founded in 1868 and named after t ...
. She applied genetic methods to mosquitoes with the aim of reducing their ability to carry viruses that can cause disease in humans and animals, and to reduce the size of mosquito populations. She also opened the St. Francis Center of Redwood City for the poor.


Education and personal life

Monica Asman was born in Germany on September 14, 1920. She was brought up in America and in 1940 she joined the Sisters of St. Francis of Penance and Christian Charity. She graduated from
University of Notre Dame The University of Notre Dame du Lac (known simply as Notre Dame; ; ND) is a Private university, private Catholic research university in Notre Dame, Indiana, United States. Founded in 1842 by members of the Congregation of Holy Cross, a Cathol ...
in 1966 with a PhD degree. In 1987 she founded the St. Francis Center for poor people in
Redwood City, California Redwood City is a city on the San Francisco Peninsula in the San Francisco Bay Area, Bay Area of Northern California, approximately south of San Francisco and northwest of San Jose, California, San Jose. The city's population was 84,292 accor ...
. In 2004 she retired to a religious residence. She died April 5, 2016.


Career

As well as her religious vocation, Asman had a successful career as a science teacher and researcher. Her reason for becoming a scientist was probably the need for science teachers at Catholic schools. Between 1944 and 1962 Asman worked as a teacher in schools run by her religious order. Making a significant change, she then began scientific research supervised by George B. Craig at the University of Notre Dame. He led a research group that was beginning to apply genetics to the mosquito ''
Aedes aegypti ''Aedes aegypti'' ( or from Greek 'hateful' and from Latin, meaning 'of Egypt'), sometimes called the Egyptian mosquito, dengue mosquito or yellow fever mosquito, is a mosquito that spreads diseases like dengue fever, yellow fever, malar ...
''. Asman's project provided her with a training in genetics and the use of
cobalt-60 Cobalt-60 (Co) is a synthetic radioactive isotope of cobalt with a half-life of 5.2714 years. It is produced artificially in nuclear reactors. Deliberate industrial production depends on neutron activation of bulk samples of the monoisotop ...
to induce mutations. This required evaluation of the effects of radiation as the mosquito developed from egg to adult to identify the level of radiation that would cause mutations without killing all the mosquitoes. After completing her doctorate, her religious order moved her to Mount Alverno Center in Redwood City, California with the objective of returning to teaching. She was appointed as an instructor in the Biology Department at
Santa Clara University Santa Clara University is a private university, private Jesuit university in Santa Clara, California, United States. Established in 1851, Santa Clara University is the oldest operating institution of higher learning in California. The university' ...
from 1966 until 1971. However, she made contact with the parasitology department at University of California, Berkeley, specifically the
arbovirus Arbovirus is an informal name for any virus that is Transmission (medicine), transmitted by arthropod Vector (epidemiology), vectors. The term ''arbovirus'' is a portmanteau word (''ar''thropod-''bo''rne ''virus''). ''Tibovirus'' (''ti''ck-''bo ...
research group led by William C. Reeves in order to continue genetics research. She began working with them, adding her skill and knowledge of genetics to their research, initially unpaid. From 1968 until 1988 she was an Associate Research Entomologist in the
University of California, Berkeley The University of California, Berkeley (UC Berkeley, Berkeley, Cal, or California), is a Public university, public Land-grant university, land-grant research university in Berkeley, California, United States. Founded in 1868 and named after t ...
. At the suggestion of the Berkeley research group, she changed from ''A. aegypti'' to the mosquito species '' Culex tarsalis'' and ''A. sierrensis'' because they were more important disease vectors in the California region. She transferred the methods she had learnt to these species and applied them in projects aiming to reduce the fertility or disease transmission of these mosquitoes. The mosquitoes were tested in controlled outdoor environments as well as in the laboratory. Some genetically altered mosquitoes were also released into the wild. The research demonstrated that there were genetic determinants for how likely mosquitoes were to carry the viruses that caused disease in humans and animals. Part of the funding for this research came from the
National Institute of Allergy and Infectious Diseases The National Institute of Allergy and Infectious Diseases (NIAID, ) is one of the 27 institutes and centers that make up the National Institutes of Health (NIH), an agency of the United States Department of Health and Human Services. NIAID's mis ...
and the United States Army Medical Research and Development Command.


Publications

Asman was the author or co-author of over 50 scientific publications. These included: * S. M. Asman, M. M. Milby, W. C. Reeves. (1990) Genetics of ''Culex tarsalis''. In: Reeves, W. C., ''Epidemiology and Control of Mosquito-borne Arboviruses in California''. Calif. Mosq. Vector Control Assocn., pp. 330–356. * Asman SM, McDonald PT and T. Prout. (1981) Field studies of genetic control systems for mosquitoes. ''Annual Review of Entomology'' 26 289–318 * Asman SM and HA Terwedow. (1980) Initial studies on the genetics of ''Aedes sierrensis''. ''Mosquito News'' 40 224–226. * Asman SM, Nelson RL, McDonald P, Milby M, Reeves W, White KD, et al. (1979) Pilot release of sex-linked multiple translocation into a Culex tarsalis field population in Kern County, California iological control ''Mosq News''. 39 248–258. * James L. Hardy, George Apperson, S. Monica Asman, and William C. Reeves. (1978
Selection of a strain of ''Culex tarsalis'' highly resistant to infection following ingestion of western equine encephalomyelitis virus.
''J. Heredity'' 27 313–321 * McDonald PT, Asman SM, Terwedow HA. (1978
Sex-linked translocations in ''Culex tarsalis'': chromosome—linkage group correlation and segregation patterns.
''J Hered''. 69 304–310. * Asman, M and KS Rai (1972) Developmental effects of ionising radiation in ''Aedes egypti''. ''J. Med Entomol''. 9 468–478 * Rai, KS, McDonald, PT and SM Asman (1970) Cytogenetics of two radiation-induced sex-linked translocations in the yellow-fever mosquito ''Aedes aegypti''. ''Genetics'' 66 635-651


References

{{DEFAULTSORT:Asman, Monica 1920 births 2016 deaths 20th-century American Roman Catholic nuns American women entomologists American women scientists University of Notre Dame alumni German emigrants to the United States