This is a list of known
combined sex-hormonal formulation
Formulation is a term used in various senses in various applications, both the material and the abstract or formal. Its fundamental meaning is the putting together of components in appropriate relationships or structures, according to a formula ...
s. Brand names and developmental code names are in parentheses.
Androgens
Injection
Marketed
*
Nandrolone decanoate/nandrolone phenylpropionate (Dinandrol)
*
Testosterone propionate/testosterone isocaproate/testosterone caproate (Androteston PP)
*
(Durasteron)
*
Testosterone propionate/testosterone enanthate (Testoviron Depot)
*
Testosterone propionate/testosterone ketolaurate (Testosid Depot)
*
(Sustanon 100)
*
(Omnadren 250)
*
(Sustanon 250)
*
(Triolandren)
*
Testosterone propionate/testosterone cypionate/prasterone (Sten)
Veterinary
Marketed
*
Boldenone acetate/boldenone cypionate/boldenone propionate/boldenone undecylenate (Equilon 100)
*
Testosterone acetate/testosterone undecanoate/testosterone valerate (Deposterona)
Estrogens
Oral
Marketed
*
Conjugated estriol (Emmenin, Progynon)
*
Conjugated estrogens
Conjugated estrogens (CEs), or conjugated equine estrogens (CEEs), sold under the brand name Premarin among others, is an estrogen medication which is used in menopausal hormone therapy and for various other indications. It is a mixture of th ...
(Premarin)
*
Esterified estrogens
Esterified estrogens (EEs), sold under the brand names Estratab and Menest among others, is an estrogen medication which is used hormone therapy for menopausal symptoms and low sex hormone levels in women, to treat breast cancer in both women ...
(Estratab, Menest)
*
Estradiol/estrone/estriol (Hormonin)
*
Ethinylestradiol/dienestrol (Foxinette)
Injection
Marketed
*
Estradiol benzoate/estradiol phenylpropionate (Dimenformon Prolongatum)
Never marketed
*
Estradiol/estradiol enanthate
Estradiol/estradiol enanthate (E2/E2-EN) is an injectable combination formulation of estradiol (E2), a short-acting estrogen, and estradiol enanthate (E2-EN), a long-acting estrogen, which was developed by Boehringer around 1960 for potential ...
Progestogens
Injection
Marketed
*
(Tocogestan)
Androgens and estrogens
Oral
Marketed
*
Chlorotrianisene/methyltestosterone (Tace mit Androgen)
*
Conjugated estrogens/methyltestosterone
Conjugated estrogens/methyltestosterone (CEEs/MT), sold under the brand name Premarin with Methyltestosterone, is a combination of conjugated estrogens (CEEs), an estrogen, and methyltestosterone (MT), an androgen and anabolic steroid (AAR), wh ...
(Premarin with Methyltestosterone)
*
Dienestrol/methyltestosterone (Estan, Lucidon)
*
Dienestrol diacetate/methyltestosterone
Dienestrol (, ) (brand names Dienoestrol, Denestrolin, Dienol and many others), also known as dienoestrol (), is a synthetic nonsteroidal estrogen medication of the stilbestrol group which is or was used to treat menopausal symptoms in the Uni ...
(Farmatest)
*
Diethylstilbestrol/methyltestosterone (Tylosterone)
*
Esterified estrogens/methyltestosterone
Esterified estrogens/methyltestosterone (EEs/MT), sold under brand names such as Covaryx, Eemt, Essian, Estratest, Menogen, and Syntest, is a hormonal preparation that combines esterified estrogens (EEs) with methyltestosterone (MT) in one ta ...
(Covaryx, Eemt, Essian, Estratest, Menogen, Syntest)
*
Ethinylestradiol/methyltestosterone (Climatone, Dumone, Duotrone, Estandron, Femandren, Femovirin, Gynetone, Lynandron, Mepilin, Mixogen, Primodian)
*
Methylestradiol/methyltestosterone (Klimanosid)
*
Methylestradiol/methyltestosterone/reserpine (Klimanosid R)
Injection
Marketed
*
Estradiol benzoate/testosterone propionate (Bothermon)
*
Estradiol benzoate/estradiol dienanthate/testosterone enanthate benzilic acid hydrazone (Climacteron, Lactimex, Lactostat)
*
Estradiol benzoate/estradiol phenylpropionate/testosterone propionate/testosterone phenylpropionate/testosterone isocaproate (Estandron Prolongatum, Lynandron Prolongatum, Mixogen
njection
*
Estradiol benzoate/testosterone isobutyrate (Femandren M, Folivirin)
*
Estradiol butyrylacetate/testosterone ketolaurate/reserpine (Klimanosid R-Depot)
*
Estradiol cypionate/testosterone cypionate (Depo-Testadiol, Femovirin)
*
Estradiol cypionate/testosterone enanthate (Supligol)
*
Estradiol valerate/prasterone enanthate (Binodian Depot, Cidodian Depot, Gynodian Depot, Klimax, Supligol NF)
*
Estradiol valerate/testosterone enanthate (Deladumone, Despamen, Ditate, Ditate-DS, Gravignost, Primodian Depot, Valertest)
Veterinary
Marketed
*
Diethylstilbestrol/methyltestosterone (Maxymin, Tylosterone)
*
Diethylstilbestrol/testosterone (Rapigain)
*
Estradiol benzoate/estradiol enanthate/testosterone enanthate (Uni-Bol)
*
Estradiol benzoate/testosterone propionate (Component E-H, Implix BF, Progro H, Synovex H)
*
Ethinylestradiol/methyltestosterone (Taril)
Estrogens and progestogens
Oral
Marketed
In
birth control pill
The combined oral contraceptive pill (COCP), often referred to as the birth control pill or colloquially as "the pill", is a type of birth control that is designed to be taken orally by women. It is the oral form of combined hormonal contra ...
s:
*
Drospirenone/estetrol
Drospirenone/estetrol, sold under the brand name Nextstellis, among others, is a fixed-dose combination medication containing drospirenone, a progestin, and estetrol, an estrogen, which is used as a combined birth control pill for the preventi ...
(Nextstellis, Drovelis, Lydisilka)
*
Estradiol/nomegestrol acetate (Naemis, Zoely)
*
Estradiol valerate/cyproterone acetate (Femilar)
*
Estradiol valerate/dienogest (Natazia, Qlaira)
*
Ethinylestradiol/chlormadinone acetate (Belara)
*
Ethinylestradiol/cyproterone acetate
Ethinylestradiol/cyproterone acetate (EE/CPA), also known as co-cyprindiol and sold under the brand names Diane and Diane-35 among others, is a combination of ethinylestradiol (EE), an estrogen, and cyproterone acetate (CPA), a progestin and a ...
(Diane, Diane-35)
*
Ethinylestradiol/desogestrel (Alenvona, Apri, Azurette, Bekyree, Bimizza, Caziant, Cesia, Cimizt, Cyclessa, Cyred, Denise, Desogen, Desirett, Emoquette, Enskyce, Gedarel, Gracial, Isibloom, Juleber, Kalliga, Kariva, Kimidess, Laurina, Linessa, Marvelon, Mercilon, Mircette, Mirvala, Novynette, Ortho-Cept, Pimtrea, Reclipsen, Regulon, Simliya, Solia, Velivet, Viorele, Volnea
)
*
Ethinylestradiol/dienogest (Valette)
*
Ethinylestradiol/dimethisterone (Oracon)
*
Ethinylestradiol/drospirenone (Yasmin, Yasminelle, Yaz)
*
Ethinylestradiol/drospirenone/levomefolic acid
Drospirenone/ethinylestradiol/levomefolic acid (EE/DRSP/LMF), sold under the brand name Beyaz among others, is a combination of ethinylestradiol (EE), an estrogen, drospirenone (DRSP), a progestogen, antimineralocorticoid, and antiandrogen, and ...
(Beyaz, Safyral)
*
Ethinylestradiol/etynodiol diacetate (Demulen)
*
Ethinylestradiol/gestodene (Femodene, Femodette, Gynera, Harmonet, Meliane, Minesse, Minulet)
*
Ethinylestradiol/levonorgestrel (Amethyst, Aviane, Balcoltra, Falmina, Levlen, Lillow, Orsythia, Vienva)
*
Ethinylestradiol/levonorgestrel/bisglycinate
*
Ethinylestradiol/levonorgestrel/ferrous fumarate
*
Ethinylestradiol/lynestrenol (Lyndiol)
*
Ethinylestradiol/medroxyprogesterone acetate (Gianda, Provest)
*
Ethinylestradiol/megestrol acetate (Nuvacon, Volidan)
*
Ethinylestradiol/norethisterone
Ethinylestradiol/norethisterone (EE/NET), or ethinylestradiol/norethindrone, is a combination birth control pill which contains ethinylestradiol (EE), an estrogen and norethisterone (NET), a progestin. It is used for birth control, symptoms o ...
(Brevicon, Norinyl 1+35, Ortho-Novum 7/7/7, Taytulla, Tri-Norinyl, Zenchent)
*
Ethinylestradiol/norethisterone/ferrous fumarate (Blisovi 24 FE, Estrostep Fe, Femcon FE, Kaitlib FE, Lo Minastrin Fe, Loestrin 24 Fe, Microgestin 24 FE)
*
Ethinylestradiol/norethisterone acetate
Ethinylestradiol/norethisterone acetate (EE/NETA), or ethinylestradiol/norethindrone acetate, is a combination of ethinylestradiol (EE) and norethisterone acetate (NETA) which is used as birth control and menopausal hormone therapy. EE is an ...
(FemHRT)
*
Ethinylestradiol/norethisterone acetate/ferrous fumarate
*
Ethinylestradiol/norgestimate (Ortho Tri-Cyclen, Sprintec)
*
Ethinylestradiol/norgestrel (Ovral)
*
Ethinylestradiol/norgestrienone (Miniplanor, Planor)
*
Ethinylestradiol/quingestanol acetate (Riglovis)
*
Ethinylestradiol sulfonate/norethisterone acetate (Deposiston)
*
Mestranol/anagestone acetate (Neo-Novum)
*
Mestranol/chlormadinone acetate (C-Quens, Lutedion)
*
Mestranol/etynodiol diacetate (Ovulen)
*
Mestranol/hydroxyprogesterone acetate (Hormolidin)
*
Mestranol/lynestrenol (Lyndiol)
*
Mestranol/norethisterone
Mestranol/norethisterone (brand names Norethin, Noriday, Norinyl, Norquen, Ortho-Novum, others) is a combination of the estrogen Mestranol and the progestin norethisterone (norethindrone) which was introduced in 1963 and was the second combined ...
(Norethin, Noriday, Norinyl, Norquen, Ortho-Novum)
*
Mestranol/noretynodrel
Mestranol/norethynodrel was the first combined oral contraceptive pill (COCP) being mestranol and norethynodrel. It sold as Enovid in the United States and as Enavid in the United Kingdom. Developed by Gregory Pincus at G. D. Searle & Company, ...
(Enavid, Enovid)
*
Quinestrol/etynodiol diacetate (Soluna)
*
Quinestrol/levonorgestrel (Yuèkětíng, Àiyuè)
*
Quinestrol/norgestrel (Compound Norgestrel)
*
Quinestrol/quingestanol acetate (Unovis)
For
menopausal hormone therapy
Hormone replacement therapy (HRT), also known as menopausal hormone therapy or postmenopausal hormone therapy, is a form of hormone therapy used to treat symptoms associated with female menopause. Effects of menopause can include symptoms such ...
and/or
gynecological disorder
Gynaecology or gynecology (see American and British English spelling differences) is the area of medicine concerned with conditions affecting the female reproductive system. It is often paired with the field of obstetrics, which focuses on pre ...
s:
*
Conjugated estrogens/medrogestone (Presomen)
*
Conjugated estrogens/medroxyprogesterone acetate (Prempro, Premphase)
*
Conjugated estrogens/norgestrel (Prempak-C)
*
Estradiol/drospirenone
Estradiol/drospirenone (E2/DRSP), sold under the brand name Angeliq, is a combination of estradiol (E2), an estrogen, and drospirenone (DRSP), a progestin, antimineralocorticoid, and antiandrogen, which is used in menopausal hormone therapy, spec ...
(Angeliq)
*
Estradiol/dydrogesterone (Femoston)
*
Estradiol/gestodene (Avaden, Avadene)
*
Estradiol/levonorgestrel
*
Estradiol/medroxyprogesterone acetate (Indivina, Tridestra)
*
Estradiol/norethisterone acetate (Activella, Activelle, Cliane, Estalis, Eviana, Evorel, Kliogest, Novofem)
*
Estradiol/norgestimate (Prefest)
*
Estradiol/progesterone (Bijuva)
*
Estradiol/trimegestone (Lovelle, Totelle)
*
Estradiol valerate/cyproterone acetate (Climen, Climen 28)
*
Estradiol valerate/estriol/levonorgestrel (CycloÖstrogynal)
*
Estradiol valerate/levonorgestrel (Cyclo-Progynova N)
*
Estradiol valerate/medroxyprogesterone acetate (Dilena, Divina, Divitren, Farludiol, Indivina, Sisare)
*
Estradiol valerate/norethisterone (Climagest, Climesse)
*
Estradiol valerate/norethisterone acetate (Cliovelle, Norestin, Trisequens)
*
Estradiol valerate/norgestrel (Cyclacur, Cyclocur, Cyclo-Progynova, Postoval, Progyluton)
*
Ethinylestradiol/ethisterone (Amenorone, Di-Pro, Duosterone, Menstrogen, Oracecron, Orasecron)
*
Mestranol/noretynodrel
Mestranol/norethynodrel was the first combined oral contraceptive pill (COCP) being mestranol and norethynodrel. It sold as Enovid in the United States and as Enavid in the United Kingdom. Developed by Gregory Pincus at G. D. Searle & Company, ...
(Enovid)
Never or not yet marketed
In
birth control pill
The combined oral contraceptive pill (COCP), often referred to as the birth control pill or colloquially as "the pill", is a type of birth control that is designed to be taken orally by women. It is the oral form of combined hormonal contra ...
s:
*
Estradiol/norethisterone (Netagen, Netagen 403)
Transdermal
Marketed
In
contraceptive patch
A contraceptive patch, also known as "the patch", is a transdermal patch applied to the skin that releases synthetic oestrogen and progestogen hormones to prevent pregnancy. They have been shown to be as effective as the combined oral contra ...
es:
*
Ethinylestradiol/norelgestromin (Evra, Ortho Evra, Xulane)
For
menopausal hormone therapy
Hormone replacement therapy (HRT), also known as menopausal hormone therapy or postmenopausal hormone therapy, is a form of hormone therapy used to treat symptoms associated with female menopause. Effects of menopause can include symptoms such ...
:
*
Estradiol/levonorgestrel (Climara Pro)
*
Estradiol/norethisterone acetate (CombiPatch)
Vaginal
Marketed
In
contraceptive vaginal ring
A contraceptive vaginal ring is a type of hormonal insert that is placed in the vagina for the purpose of birth control. The rings themselves utilize a plastic polymer matrix that is inlaid or embedded with contraceptive drug. This drug, often one ...
s:
*
Ethinylestradiol/etonogestrel (Circlet, NuvaRing)
*
Segesterone acetate/ethinylestradiol (Annovera)
Injection
Marketed
In
combined injectable contraceptive
Combined injectable contraceptives (CICs) are a form of hormonal birth control for women. They consist of monthly injections of combined formulations containing an estrogen and a progestin to prevent pregnancy.
CICs are different from progestog ...
s:
*
Estradiol/megestrol acetate (Mego-E, Chinese Injectable No. 2)
*
Estradiol benzoate/estradiol valerate/hydroxyprogesterone caproate (Sin-Ol)
*
Estradiol benzoate butyrate/algestone acetophenide (Redimen, Soluna, Unijab)
*
Estradiol cypionate/hydroxyprogesterone caproate
Estradiol cypionate/hydroxyprogesterone caproate (EC/OHPC), sold under the brand name Sinbios, is a combination medication of estradiol cypionate (EC), an estrogen, and hydroxyprogesterone caproate (OHPC), a progestin, which was reportedly used a ...
(Sinbios)
*
Estradiol cypionate/medroxyprogesterone acetate
Estradiol cypionate/medroxyprogesterone acetate (EC/MPA), sold under the brand name Cyclofem among others, is a form of combined injectable birth control. It contains estradiol cypionate (EC), an estrogen, and medroxyprogesterone acetate (MPA), ...
(Cyclo-Provera, Cyclofem, Lunelle)
*
Estradiol enanthate/algestone acetophenide (Anafertin, Deladroxate, Perlutan, Topasel, Yectames)
*
Estradiol valerate/hydroxyprogesterone caproate (Chinese Injectable No. 1)
*
Estradiol valerate/norethisterone enanthate (Mesigyna, Mesygest)
For
menopausal hormone therapy
Hormone replacement therapy (HRT), also known as menopausal hormone therapy or postmenopausal hormone therapy, is a form of hormone therapy used to treat symptoms associated with female menopause. Effects of menopause can include symptoms such ...
,
gynecological disorder
Gynaecology or gynecology (see American and British English spelling differences) is the area of medicine concerned with conditions affecting the female reproductive system. It is often paired with the field of obstetrics, which focuses on pre ...
s,
habitual abortion, and other indications:
*
Estradiol/progesterone (Juvenum)
*
Estradiol benzoate/hydroxyprogesterone caproate (Primosiston)
*
Estradiol benzoate/progesterone
Estradiol benzoate/progesterone (EB/P4), sold under the brand names Duogynon and Sistocyclin among others, is a combination medication of estradiol benzoate (EB), an estrogen, and progesterone (P4), a progestogen. It has been formulated both as ...
(Duogynon, Sistocyclin)
*
Estradiol dipropionate/hydroxyprogesterone caproate (EP Hormone Depot)
*
Estradiol hemisuccinate/progesterone (Hosterona)
*
Estradiol pivalate/progesterone (Estrotate with Progesterone)
*
Estradiol valerate/hydroxyprogesterone caproate (Gravibinan, Gravibinon)
*
Estrone/progesterone (Synergon)
Never marketed
In
combined injectable contraceptive
Combined injectable contraceptives (CICs) are a form of hormonal birth control for women. They consist of monthly injections of combined formulations containing an estrogen and a progestin to prevent pregnancy.
CICs are different from progestog ...
s:
*
Estradiol/progesterone (in microspheres and macrocrystalline aqueous suspension)
*
Estradiol undecylate/norethisterone enanthate
*
Estradiol valerate/megestrol acetate
*
Estradiol valerate/methenmadinone caproate (Lutofollin)
*
Polyestradiol phosphate/medroxyprogesterone acetate
* Additional preparations listed at
Combined injectable birth control § Research
For other indications:
*
Estradiol valerate/gestonorone caproate (SH-834, SH-8.0834)
Veterinary
Marketed
*
Estradiol benzoate/progesterone
Estradiol benzoate/progesterone (EB/P4), sold under the brand names Duogynon and Sistocyclin among others, is a combination medication of estradiol benzoate (EB), an estrogen, and progesterone (P4), a progestogen. It has been formulated both as ...
(Component E-S, Implix BM, Synovex C, Synovex S)
*
Estradiol valerate/norgestomet (Syncro-Mate-B)
Androgens and progestogens
Oral
Marketed
*
Methyltestosterone/ethisterone (Androgeston)
Injection
Marketed
*
Testosterone propionate/progesterone (Testoluton)
[Archived copy](_blank)
Veterinary
Marketed
*
Danazol/megestrol acetate (Dogalact)
*
Nandrolone decanoate/methandriol dipropionate (Filybol, Tribolin)
*
Nandrolone phenylpropionate/methandriol dipropionate (RWR)
Estrogens, progestogens, and androgens
Oral
Marketed
*
Methylestradiol/normethandrone (Ginecosid, Ginecoside, Mediol, Renodiol)
Not yet marketed
*
Ethinylestradiol/drospirenone/prasterone
Ethinylestradiol/drospirenone/prasterone (EE/DRSP/DHEA), known under developmental code names like Androgen Restored Contraceptive (ARC), Female Balance Pill, Pill-Plus, and Triple Oral Contraceptive (Triple OC), is a combination of ethinylestrad ...
Sublingual
Marketed
*
Estradiol/progesterone/methyltestosterone (Trihormonal)
*
Ethinylestradiol/ethisterone/methyltestosterone (Trinestryl, Trimone Sublets)
Injection
Marketed
*
Estradiol benzoate/progesterone/methandriol dipropionate
Estradiol benzoate/progesterone/methandriol dipropionate (EB/P4/MADP), sold under the brand name Progestandron (Organon), is an injectable combination medication of estradiol benzoate (EB), an estrogen, progesterone (P4), a progestogen, and meth ...
(Progestandron)
*
Estradiol benzoate/progesterone/testosterone propionate (Lukestra, Steratrin, Trihormonal, Trinestryl)
*
Estradiol benzoate/estradiol valerate/norethisterone acetate/testosterone enanthate (Ablacton)
*
Estradiol dibutyrate/hydroxyprogesterone heptanoate/testosterone caproate (Triormon Depositum)
*
Estradiol diundecylate/hydroxyprogesterone heptanoate/testosterone cyclohexylpropionate (Trioestrine Retard)
*
Estradiol hexahydrobenzoate/hydroxyprogesterone caproate/testosterone hexahydrobenzoate (Trinestril AP)
*
Estrone/progesterone/testosterone (Tristeron, Tristerone)
Never marketed
*
Estrapronicate/hydroxyprogesterone heptanoate/nandrolone undecanoate (Trophobolene, Trophoboline)
Veterinary
Marketed
*
Estradiol/trenbolone acetate (Component, Compudose-G, Progro TE-H, Revalor, Synovex)
*
Estradiol benzoate/trenbolone acetate (Synovex Choice, Synovex One, Synovex Plus, Synovex with Trenbolone Acetate)
Miscellaneous
Oral
Marketed
*
Conjugated estrogens/bazedoxifene
Bazedoxifene/conjugated estrogens, sold under the brand name Duavee among others, is a fixed-dose combination medication for the treatment of menopause symptoms and postmenopausal osteoporosis. It contains the selective estrogen receptor modul ...
(Duavee)
Never marketed
*
Esterified estrogens/raloxifene
*
Estradiol/raloxifene
Transdermal
Marketed
*
Estradiol benzoate/prednisolone/salicylic acid (Alpicort E, Alpicort F, Alpicort Plus)
Vaginal
Marketed
*
Estradiol benzoate/gentamicin/hydrocortisone/nystatin (Cridermol Fem, Ginabiot, Ginecovan)
*
Estradiol benzoate/monalazone (Malun-25)
Mixed
Marketed
*
Goserelin/bicalutamide (ZolaCos CP)
*
Leuprorelin/norethisterone acetate (Lupaneta Pack)
See also
*
List of sex-hormonal medications available in the United States
*
List of sex-hormonal aqueous suspensions
*
List of steroid esters
*
List of marketed estradiol benzoate formulations
References
{{DEFAULTSORT:Combined sex-hormonal preparations
Anabolic–androgenic steroids
Sex-hormonal preparations
Drug-related lists
Estrogens
Progestogens