The mir-BART2
microRNA precursor found in Human herpesvirus 4 (
Epstein–Barr virus) and Cercopithicine herpesvirus 15. mir-BART2 is expressed in all stages of infection but expression is significantly elevated in the
lytic stage. In Epstein-Barr virus, mir-BART2 is found in the
intron
An intron is any nucleotide sequence within a gene that is not expressed or operative in the final RNA product. The word ''intron'' is derived from the term ''intragenic region'', i.e. a region inside a gene."The notion of the cistron .e., gene. ...
ic regions of the
BART (Bam HI-A region rightward transcript)
gene whose function is unknown. mir-BART2 is thought to target the virally encoded
DNA polymerase BALF5 for degradation. The mature sequence is excised from the 5' arm of the
hairpin.
References
External links
*
VMR_0123in the VIRmiRNA database
MicroRNA
MicroRNA precursor families
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