Migrastatin is an organic compound which naturally occurs in the ''
Streptomyces platensis
''Streptomyces platensis'' is a bacterium species from the genus of ''Streptomyces'' which has been isolated from soil.Deutsche Sammlung von Mikroorganismen und Zellkulturenbr>/ref> ''Streptomyces platensis'' produces oxytetracycline, platensim ...
'' bacteria. Migrastatin and several of its analogues (including
Isomigrastatin
Isomigrastatin is an analogue of migrastatin, an organic compound that naturally occurs in the '' Streptomyces platensis'' bacteria. Isomigrastatin has shown promise as a drug in the treatment of cancer
Cancer is a group of diseases invo ...
) have shown to have potential in treating
cancer
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal bl ...
, as it inhibits the
metastasis
Metastasis is a pathogenic agent's spread from an initial or primary site to a different or secondary site within the host's body; the term is typically used when referring to metastasis by a cancerous tumor. The newly pathological sites, then, ...
of cancer cells.
References
Macrolides
Glutarimides
Alcohols
Methoxy compounds
Ketones
{{organic-compound-stub