Micropolygyria is a
neuronal migration disorder
Neuronal migration disorder (NMD) refers to a heterogenous group of disorders that, it is supposed, share the same etiopathological mechanism: a variable degree of disruption in the migration of neuroblasts during neurogenesis. The neuronal migra ...
, a developmental anomaly of the brain characterized by development of numerous small convolutions (
microgyri), causing
intellectual disability
Intellectual disability (ID), also known as general learning disability (in the United Kingdom), and formerly mental retardation (in the United States), Rosa's Law, Pub. L. 111-256124 Stat. 2643(2010).Archive is a generalized neurodevelopmental ...
and/or other neurological disorders. It is present in a number of specific
neurological diseases
Neurological disorders represent a complex array of medical conditions that fundamentally disrupt the functioning of the nervous system. These disorders affect the brain, spinal cord, and nerve networks, presenting unique diagnosis, treatment, and ...
, notably
multiple sclerosis
Multiple sclerosis (MS) is an autoimmune disease resulting in damage to myelinthe insulating covers of nerve cellsin the brain and spinal cord. As a demyelinating disease, MS disrupts the nervous system's ability to Action potential, transmit ...
and
:Fukuyama congenital muscular dystrophy, a specific disease cause by mutation in the
:Fukutin gene (FKTN).
See also
*
Glia limitans
The glia limitans, or the glial limiting membrane, is a thin barrier of astrocyte foot processes associated with the brain parenchyma, parenchymal basal lamina surrounding the brain and spinal cord. It is the outermost layer of neural tissue, and ...
References
External links
Brain disorders
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