Michael Lesch (actor)
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Michael Lesch (June 30, 1939 – March 19, 2008) was an American physician and medical educator who helped identify an important genetic disorder associated with intellectual disability and self-mutilation. This disease is now known as the
Lesch–Nyhan syndrome Lesch–Nyhan syndrome (LNS) is a rare inherited disorder caused by a deficiency of the enzyme hypoxanthine-guanine phosphoribosyltransferase (HGPRT). This deficiency occurs due to mutations in the '' HPRT1'' gene located on the X chromosome. ...
. In the mid-1960s when the
syndrome A syndrome is a set of medical signs and symptoms which are correlated with each other and often associated with a particular disease or disorder. The word derives from the Greek language, Greek σύνδρομον, meaning "concurrence". When a sy ...
was discovered, Lesch was a research associate working at the Laboratory of General and Comparative Biochemistry at the NIH National Institute of Mental Health in Bethesda, Maryland.
William Nyhan William Leo Nyhan (born March 13, 1926) is an American physician best known as the co-discoverer of Lesch–Nyhan syndrome. Nyhan currently serves as professor of pediatrics at University of California, San Diego School of Medicine in La Jolla, ...
, a pediatrician and biochemical geneticist, was his mentor. Lesch was 30 years old when he discovered the disease. Lesch completed his medical training at
Johns Hopkins Johns Hopkins (May 19, 1795 – December 24, 1873) was an American merchant, investor, and philanthropist. Born on a plantation, he left his home to start a career at the age of 17, and settled in Baltimore, Maryland, where he remained for mos ...
in the Osler Medical Service in 1964. While at Hopkins he earned the distinguished honor of president,
Alpha Omega Alpha Alpha Omega Alpha Honor Medical Society () is an honor society in the field of medicine. It has active chapters in 132 Liaison Committee on Medical Education, LCME-accredited medical schools in the United States and Lebanon. It annually elects ove ...
, The Johns Hopkins University Chapter.


Biography

Michael Lesch was born in 1939 in
Queens Queens is the largest by area of the Boroughs of New York City, five boroughs of New York City, coextensive with Queens County, in the U.S. state of New York (state), New York. Located near the western end of Long Island, it is bordered by the ...
in
New York City New York, often called New York City (NYC), is the most populous city in the United States, located at the southern tip of New York State on one of the world's largest natural harbors. The city comprises five boroughs, each coextensive w ...
. He attended
Columbia University Columbia University in the City of New York, commonly referred to as Columbia University, is a Private university, private Ivy League research university in New York City. Established in 1754 as King's College on the grounds of Trinity Churc ...
, attaining
Phi Beta Kappa The Phi Beta Kappa Society () is the oldest academic honor society in the United States. It was founded in 1776 at the College of William & Mary in Virginia. Phi Beta Kappa aims to promote and advocate excellence in the liberal arts and sciences, ...
during his junior year and graduating
summa cum laude Latin honors are a system of Latin phrases used in some colleges and universities to indicate the level of distinction with which an academic degree has been earned. The system is primarily used in the United States. It is also used in some Sout ...
, before entering medical school at
Johns Hopkins School of Medicine The Johns Hopkins University School of Medicine (JHUSOM) is the medical school of Johns Hopkins University, a private research university in Baltimore, Maryland. Established in 1893 following the construction of the Johns Hopkins Hospital, th ...
. After receiving his medical degree, Lesch became an
internist Internal medicine, also known as general medicine in Commonwealth nations, is a medical specialty for medical doctors focused on the prevention, diagnosis, and treatment of diseases in adults. Its namesake stems from "treatment of diseases of th ...
and specialized in
cardiology Cardiology () is the study of the heart. Cardiology is a branch of medicine that deals with disorders of the heart and the cardiovascular system. The field includes medical diagnosis and treatment of congenital heart defects, coronary artery di ...
. In the 1970s Lesch distinguished himself early on in Boston, Massachusetts, at the
Peter Bent Brigham Hospital Brigham and Women's Hospital (BWH or The Brigham) is a teaching hospital of Harvard Medical School and the largest hospital in the Longwood Medical Area in Boston, Massachusetts. Along with Massachusetts General Hospital, it is one of the two ...
and the
Harvard Medical School Harvard Medical School (HMS) is the medical school of Harvard University and is located in the Longwood Medical and Academic Area, Longwood Medical Area in Boston, Massachusetts. Founded in 1782, HMS is the third oldest medical school in the Un ...
. In 1971-72 he was appointed chief resident at the Brigham Hospital. Between the years of 1974–1976, he became an associate professor of medicine at the Harvard Medical School and the director of the S.A. Levine Cardiac Center at the Peter Bent Brigham Hospital. In 1976, he moved with his family from Boston to Chicago, where he took the position of Chief, Section of Cardiology, Northwestern University Medical School, Northwestern Memorial Hospital, Chicago, Illinois, a position he held for 12 years. At age 37, he was one of the youngest Section Chiefs ever appointed at Northwestern in the Department of Cardiology. During his tenure in Chicago, he held the position of Vice President of the Chicago Heart Association from 1978–80. From 1982-1983 he was the president of the Chicago Heart Association. In 1982 he was also listed for the first time in the Annuals of Who's Who in America. In 1983–85, he was appointed to the board of trustees, University Space Research Association (NASA). From 1984–87, Lesch was asked to chair the Chicago Heart Association's Cardiac Exhibition Committee at the Chicago Museum of Science and Industry. That Committee developed a four-chamber heart that museum visitors could walk-thru to better understand the heart's physiology. In 1988, Lesch was awarded The Heart of the Year Award, from the Metropolitan Chicago Chapter of the American Heart Association. In 1989, Lesch moved to Michigan, where he became chairman of the Department of Medicine at the Henry Ford Hospital and Health System until 1998. In 1993 he was appointed to the board of trustees at the Henry Ford Hospital. In 1998, Lesch was named chairman of Department of Medicine at St. Luke's-Roosevelt Hospital Center (now
Mount Sinai Morningside Mount Sinai Morningside, formerly known as Mount Sinai St. Luke's, is a teaching hospital located in the Morningside Heights, Manhattan, Morningside Heights neighborhood of Manhattan in New York City. It is affiliated with the Icahn School of M ...
) in New York City and Professor of Medicine there at the
Columbia University College of Physicians and Surgeons The Columbia University College of Physicians and Surgeons (officially known as Columbia University Roy and Diana Vagelos College of Physicians and Surgeons) is the medical school of Columbia University, located at the Columbia University Irvin ...
. A position he held until his death in 2008. In 1999 he was appointed to the board of trustees, St. Luke's-Roosevelt Hospital Center and in 2002 he became the Medical Director for the Cardiac Service Line at Continuum Health Partners. During his career, Lesch lectured and taught extensively as a visiting professor abroad. In 1977 he was a visiting Professor of Cardiology at the Sree Chitra Tirunal Medical Center in Trivandrum, India. In 1984 he was an invited lecturer at the International Symposium on Stress and Heart Disease in Winnipeg, Canada. In 1986 Dr Lesch became a Fulbright Visiting Professor of Cardiology at the Egyptian Cardiology Society and a Fulbright Visiting Professor of Cardiology, at the Portuguese Society of Cardiology. That same year, Lesch was named an Honorary Member of the Portuguese Society of Cardiology. In 1993, Lesch was a visiting Professor of Cardiology at the Universidad Peruana Cayetano Heredia in Lima, Peru. In 1999, Lesch was a visiting Cardiologist at the Sakakibara Heart Institute in Tokyo, Japan. And in 2000, he was a Visiting Professor of Cardiology, at the Tohoku University School of Medicine in Sendai, Japan. Lesch earned the distinction of being listed in the annals of The Best Doctors in America starting in 2003, an honor he retained every year until his death. Lesch was a prolific writer, publisher and editor. From 1971 until his death, he was the co-editor of the periodical, Progress in Cardiovascular Diseases. From 1975-76 he was an Associate Editor at The New England Journal of Medicine. From 1976-79 he was on the Editorial Board of Cardiovascular Medicine. From 1978-82 he was on the Editorial Board of the American Journal of Cardiology. From 1980-92 he was on the Editorial Board of American Heart Journal. From 1987-96 he was on the Editorial Board of the American Journal of Cardiac Imaging. From 1996 until his death, he was on the Editorial Board, American Journal of Geriatric Cardiology. Lesch was also an avid fly fisherman who fished the lakes and rivers of Canada, Alaska, Chile, the Arctic, the Amazon and Argentina. Lesch died unexpectedly in his sleep while in
Argentina Argentina, officially the Argentine Republic, is a country in the southern half of South America. It covers an area of , making it the List of South American countries by area, second-largest country in South America after Brazil, the fourt ...
on a fishing trip to the
Gallegos River The Gallegos River () is a river in the Argentine province of Santa Cruz, on whose estuary lies Río Gallegos city, capital of the province. Given that its basin reaches only the fringes of the Andes mountains it classifies as a sub-Andean rive ...
. He is survived by his wife, Bella Lesch, two children (Leah Lesch and Ian Lesch) and six grandchildren.


References


External links

*
Obituary for Michael Lesch
by Lawrence K. Altman in
The New York Times ''The New York Times'' (''NYT'') is an American daily newspaper based in New York City. ''The New York Times'' covers domestic, national, and international news, and publishes opinion pieces, investigative reports, and reviews. As one of ...
{{DEFAULTSORT:Lesch, Michael 1939 births 2008 deaths American cardiologists Fellows of the American College of Cardiology Feinberg School of Medicine faculty