Methylatropine, sold under the brand name Eumydrin, is a
belladonna derivative.
In 1902, the
Bayer Company introduced methylatropine, a quaternary ammonium salt of atropine, as a mydriatic for dilation of the pupil during ophthalmic examination under the brand name of Eumydrin. Because of its highly polar nature it penetrated less readily into the central nervous system than did atropine; hence it was introduced for relieving pyloric spasm in infants.
The blocking potency of methylatropine is approximately 10-20 times higher than that of
atropine
Atropine is a tropane alkaloid and anticholinergic medication used to treat certain types of nerve agent and pesticide poisonings as well as some types of slow heart rate, and to decrease saliva production during surgery. It is typically give ...
at neuromuscular and ganglionic synapses.
See also
*
Apoatropine
References
Muscarinic antagonists
Quaternary ammonium compounds
Tropanes
Primary alcohols
Carboxylate esters
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