Methyl Caffeate
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Methyl caffeate is an ester of
caffeic acid Caffeic acid is an organic compound with the formula . It is a polyphenol with a key role in scavenging reactive oxygen species (ROS) generated in energy metabolism. Caffeic acid is also one major polyphenol responsible for maintaining normal le ...
, a naturally occurring phenolic compound. It is an
α-glucosidase In biochemistry, glycoside hydrolases (also called glycosidases or glycosyl hydrolases) are a class of enzymes which catalyze the hydrolysis of glycosidic bonds in complex sugars. They are extremely common enzymes, with roles in nature includi ...
inhibitor. Its physical form is a powder.


Natural occurrences

Methyl caffeate can be found in the fruit of ''
Solanum torvum ''Solanum torvum'', also known as pendejera, turkey berry, devil's fig, pea eggplant, platebrush or susumber, is a bushy, erect and spiny perennial plant used horticulturally as a rootstock for eggplant. Grafted plants are very vigorous and t ...
''.


Health effect

Methyl caffeate shows an
antidiabetic Drugs used in diabetes treat types of diabetes mellitus by decreasing glucose levels in the blood. With the exception of insulin, most GLP-1 receptor agonists ( liraglutide, exenatide, and others), and pramlintide, all diabetes medications a ...
effect in
streptozotocin Streptozotocin or streptozocin ( INN, USP) (STZ) is a naturally occurring alkylating antineoplastic agent that is particularly toxic to the insulin-producing beta cells of the pancreas in mammals. It is used in medicine for treating certain can ...
-induced diabetic rats.


References

O-methylated hydroxycinnamic acids Hydroxycinnamic acid esters Catechols {{aromatic-stub