Meshack is a masculine given name. Notable people with the name include:
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Dumezweni Meshack Mthimkhulu, Motswana politician
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Meshack Abel Mwankina (born 1987), Tanzanian footballer
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Meshack Asare (born 1945), Ghanian writer
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Meshack Franklin (1722–1839), American politician
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Meshack Kondwani, Zimbabwean boxer
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Meshack Lufile (born 1992), Canadian basketball player
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Meshack Maphangule (born 1991), South African footballer
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Meshack Mavuso (born 1977), South African actor
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Meshack Opulukwa (born 1967), Tanzanian politician
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Meshack Radebe (1948/1949–2021), South African politician
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Meshack Ratliff (1832–1922), American Army officer and politician
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Meshack Roberts, American slave, minister and politician
{{Given name, cat=Masculine given names