Merle Alden Sande (September 2, 1939 – November 4, 2007) was a leading American infectious-diseases expert whose early recognition of the looming public health crisis posed by
AIDS led to the development of basic protocols for how to handle infected patients. He graduated from
Washington State University
Washington State University (Washington State, WSU, or informally Wazzu) is a public land-grant research university with its flagship, and oldest, campus in Pullman, Washington. Founded in 1890, WSU is also one of the oldest land-grant uni ...
and received his MD degree from the
University of Washington
The University of Washington (UW, simply Washington, or informally U-Dub) is a public research university in Seattle, Washington.
Founded in 1861, Washington is one of the oldest universities on the West Coast; it was established in Seat ...
, School of Medicine in Seattle.
Biography
Sande was a professor of Internal Medicine from 1971 to 1980 at the
University of Virginia
The University of Virginia (UVA) is a public research university in Charlottesville, Virginia. Founded in 1819 by Thomas Jefferson, the university is ranked among the top academic institutions in the United States, with College admission ...
, where he performed research in mice on bacterial
meningitis
Meningitis is acute or chronic inflammation of the protective membranes covering the brain and spinal cord, collectively called the meninges. The most common symptoms are fever, headache, and neck stiffness. Other symptoms include confusion ...
therapies such as novel antibiotics and corticosteroids. Dr Sande was Chief of Medical Services at
San Francisco General Hospital in 1981 when he recognized a pattern of gay men being admitted with the rare
pneumocystis
The Pneumocystidomycetes are a class of ascomycete fungi. It includes the single order Pneumocystidales, which contains the single monotypic family Pneumocystidaceae, which in turn contains the genus
Genus ( plural genera ) is a taxonomic ...
pneumonia. His efforts on behalf of these patients resulted in the formation of an AIDS ward at
San Francisco General Hospital and later an AIDS outpatient clinic. Teaming with such experts as
Julie Gerberding
Julie Louise Gerberding (born August 22, 1955) is an American infectious disease expert who was the first woman to serve as the director of the U.S. Centers for Disease Control and Prevention (CDC). As of May 2022, she is the CEO of the Foundat ...
and
Paul Volberding
Paul A. Volberding is an American physician who is best known for his pioneering work in treating people with HIV.
Work
In 1983, Volberding founded the first inpatient ward for persons with AIDS in the San Francisco General Hospital. He worked ...
he helped to craft what became known as the ''San Francisco model'' of AIDS therapy, a comprehensive, rational approach to care that avoided the fear and paranoia surrounding the disease at that time. The model addressed a need for infection-control guidelines, clinical studies and research financing and became a template for AIDS centers nationwide. Sande helped found to the Gladstone Institute of Virology and Immunology, which performed trials on some of the first anti-retrovirals such as
zidovudine
Zidovudine (ZDV), also known as azidothymidine (AZT), is an antiretroviral medication used to prevent and treat HIV/AIDS. It is generally recommended for use in combination with other antiretrovirals. It may be used to prevent mother-to-chil ...
. He also helped to found the
Infectious Diseases Institute
The Infectious Diseases Institute (IDI), established within Makerere University, is a Ugandan not-for-profit organization which aims to strengthen health systems in Africa, with a strong emphasis on infectious diseases; through research and capac ...
at the
Makerere University
Makerere University, Kampala (; Mak) is Uganda's largest and oldest institution of higher learning, first established as a technical school in 1922. It became an independent national university in 1970. Today, Makerere University is composed of n ...
College of Health Sciences in
Kampala
Kampala (, ) is the capital and largest city of Uganda. The city proper has a population of 1,680,000 and is divided into the five political divisions of Kampala Central Division, Kawempe Division, Makindye Division, Nakawa Division, and ...
, Uganda a major center for HIV education and research in Africa. Sande was a professor of Medicine at
University of California, San Francisco
The University of California, San Francisco (UCSF) is a public land-grant research university in San Francisco, California. It is part of the University of California system and is dedicated entirely to health science and life science. It co ...
from 1980 to 1996, chairman of the department internal medicine at
University of Utah
The University of Utah (U of U, UofU, or simply The U) is a public research university in Salt Lake City, Utah. It is the flagship institution of the Utah System of Higher Education. The university was established in 1850 as the University of D ...
from 1996 to 2005 and Professor of medicine at
University of Washington
The University of Washington (UW, simply Washington, or informally U-Dub) is a public research university in Seattle, Washington.
Founded in 1861, Washington is one of the oldest universities on the West Coast; it was established in Seat ...
from 2005 until his death and president of the
Infectious Diseases Society of America
The Infectious Diseases Society of America (IDSA) is a medical association representing physicians, scientists and other health care professionals who specialize in infectious diseases. It was founded in 1963 and is based in Arlington, Virginia. ...
from 1993 to 1994. He was also the editor of two highly regarded medical references ''The Medical Management of AIDS'' and ''The Sanford Guide to Antimicrobial Therapy''.
Sande gave in 2003 the Jeremiah Metzger Lecture and in 2004 the
Wesley Spink Wesley William Spink (December 17, 1904 – May 14, 1988) was an American physician, medical school professor, college coach, and medical researcher. He was "an internationally recognized authority on infectious diseases and is credited with control ...
Memorial Lecture.
He also gave the always popular and well attended annual update in Infectious Diseases at the
American College of Physicians
The American College of Physicians (ACP) is a national organization of internists, who specialize in the diagnosis, treatment, and care of adults.Sokanu "What is an Internist?" Retrieved October 20, 2014 With 161,000 members, ACP is the largest ...
annual meeting as well as the clinical case presentations at the
Infectious Diseases Society of America
The Infectious Diseases Society of America (IDSA) is a medical association representing physicians, scientists and other health care professionals who specialize in infectious diseases. It was founded in 1963 and is based in Arlington, Virginia. ...
annual meeting.
Sande died from complications of
Multiple Myeloma
Multiple myeloma (MM), also known as plasma cell myeloma and simply myeloma, is a cancer of plasma cells, a type of white blood cell that normally produces antibodies. Often, no symptoms are noticed initially. As it progresses, bone pain, ane ...
in 2007.
Selected bibliography
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References
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External links
obituaries New York Times ObituaryIDSA Newsletter Obituary
{{DEFAULTSORT:Sande, Merle
1939 births
2007 deaths
American infectious disease physicians
Deaths from cancer in Washington (state)
University of Washington School of Medicine alumni
University of Virginia School of Medicine faculty
University of Utah faculty
University of California, San Francisco faculty
University of Washington faculty
Deaths from multiple myeloma
HIV/AIDS researchers