''Megathura crenulata'' is a northeastern

Pacific Ocean The Pacific Ocean is the largest and deepest of Earth's five Borders of the oceans, oceanic divisions. It extends from the Arctic Ocean in the north to the Southern Ocean, or, depending on the definition, to Antarctica in the south, and is ...

species of

limpet Limpets are a group of aquatic snails with a conical gastropod shell, shell shape (patelliform) and a strong, muscular foot. This general category of conical shell is known as "patelliform" (dish-shaped). Existing within the class Gastropoda, ...

in the family

Fissurellidae Fissurellidae, common name the keyhole limpets and slit limpets, is a taxonomic family of small to medium-sized limpet-like sea snails, marine gastropod molluscs in the clade Vetigastropoda.Rosenberg, G. (2012). Fissurellidae. Accessed throu ...

Rosenberg, G. (2015)
''Megathura crenulata'' (Sowerby I, 1825).
''In'': MolluscaBase (2015). Accessed through: World Register of Marine Species on 16 February 2016. known commonly as the great keyhole limpet''Megathura crenulata''.
Hardy's Internet Guide to Marine Gastropods. or giant keyhole limpet.
SeaLifeBase. ''Megathura'' is a monotypic genus; in other words, this is the only species in that genus. This species occurs along the rocky coast of western North America, its distribution extending from

Southern California Southern California (commonly shortened to SoCal) is a geographic and Cultural area, cultural List of regions of California, region that generally comprises the southern portion of the U.S. state of California. Its densely populated coastal reg ...

to the Baja California peninsula in

Mexico Mexico, officially the United Mexican States, is a country in North America. It is the northernmost country in Latin America, and borders the United States to the north, and Guatemala and Belize to the southeast; while having maritime boundar ...

. It is found in the

intertidal zone The intertidal zone or foreshore is the area above water level at low tide and underwater at high tide; in other words, it is the part of the littoral zone within the tidal range. This area can include several types of habitats with various ...

and in the sea up to a depth of 33 meters.

Description

Limpets of this family have a hole at the top of the shell, the portal through which waste products are released. This makes them different from the true limpets, which release waste from the mantle beneath the shell. This species is one of the largest keyhole limpets.

Biology

This species consumes a varied diet of plant, animal, protist, and algal material. It has been noted to consume filamentous

cyanobacteria Cyanobacteria ( ) are a group of autotrophic gram-negative bacteria that can obtain biological energy via oxygenic photosynthesis. The name "cyanobacteria" () refers to their bluish green (cyan) color, which forms the basis of cyanobacteri ...

diatom A diatom (Neo-Latin ''diatoma'') is any member of a large group comprising several Genus, genera of algae, specifically microalgae, found in the oceans, waterways and soils of the world. Living diatoms make up a significant portion of Earth's B ...

brown Brown is a color. It can be considered a composite color, but it is mainly a darker shade of orange. In the CMYK color model used in printing and painting, brown is usually made by combining the colors Orange (colour), orange and black. In the ...

and

red algae Red algae, or Rhodophyta (, ; ), make up one of the oldest groups of eukaryotic algae. The Rhodophyta comprises one of the largest Phylum, phyla of algae, containing over 7,000 recognized species within over 900 Genus, genera amidst ongoing taxon ...

s such as

seaweed Seaweed, or macroalgae, refers to thousands of species of macroscopic, multicellular, marine algae. The term includes some types of ''Rhodophyta'' (red), '' Phaeophyta'' (brown) and ''Chlorophyta'' (green) macroalgae. Seaweed species such as ...

seagrass Seagrasses are the only flowering plants which grow in marine (ocean), marine environments. There are about 60 species of fully marine seagrasses which belong to four Family (biology), families (Posidoniaceae, Zosteraceae, Hydrocharitaceae and ...

, forams,

hydrozoa Hydrozoa (hydrozoans; from Ancient Greek ('; "water") and ('; "animals")) is a taxonomy (biology), taxonomic class (biology), class of individually very small, predatory animals, some solitary and some colonial, most of which inhabit saline wat ...

ns,

bryozoa Bryozoa (also known as the Polyzoa, Ectoprocta or commonly as moss animals) are a phylum of simple, aquatic animal, aquatic invertebrate animals, nearly all living in sedentary Colony (biology), colonies. Typically about long, they have a spe ...

ns,

nematode The nematodes ( or ; ; ), roundworms or eelworms constitute the phylum Nematoda. Species in the phylum inhabit a broad range of environments. Most species are free-living, feeding on microorganisms, but many are parasitic. Parasitic worms (h ...

bivalves Bivalvia () or bivalves, in previous centuries referred to as the Lamellibranchiata and Pelecypoda, is a class of aquatic molluscs (marine and freshwater) that have laterally compressed soft bodies enclosed by a calcified exoskeleton consis ...

gastropods Gastropods (), commonly known as slugs and snails, belong to a large taxonomic class of invertebrates within the phylum Mollusca called Gastropoda (). This class comprises snails and slugs from saltwater, freshwater, and from the land. Ther ...

crustacean Crustaceans (from Latin meaning: "those with shells" or "crusted ones") are invertebrate animals that constitute one group of arthropods that are traditionally a part of the subphylum Crustacea (), a large, diverse group of mainly aquatic arthrop ...

s, and

tunicate Tunicates are marine invertebrates belonging to the subphylum Tunicata ( ). This grouping is part of the Chordata, a phylum which includes all animals with dorsal nerve cords and notochords (including vertebrates). The subphylum was at one time ...

s. The larger part of its diet is composed of brown and red algae, tunicates, hydrozoans of the genus ''

Eudendrium ''Eudendrium'' is a large genus of hydroids (Hydrozoa), one of two in the family Eudendriidae. These animals are marine cnidarias in the family Eudendriidae Eudendriidae is a taxonomic family of hydroids (Hydrozoa). The family contains aro ...

'' and bryozoans of the genus '' Crisia''. ''M. crenulata'' has been used for experimental studies on gamete agglutination. Its blood contains a

hemocyanin Hemocyanins (also spelled haemocyanins and abbreviated Hc) are proteins that transport oxygen throughout the bodies of some invertebrate animals. These metalloproteins contain two copper atoms that reversibly bind a single oxygen molecule (O2 ...

that appears blue due to its copper content. This protein carries oxygen as

hemoglobin Hemoglobin (haemoglobin, Hb or Hgb) is a protein containing iron that facilitates the transportation of oxygen in red blood cells. Almost all vertebrates contain hemoglobin, with the sole exception of the fish family Channichthyidae. Hemoglobin ...

does in vertebrates. Unlike hemoglobin, the hemocyanin is not bound to cells but is simply dissolved in the hemolymph, the fluid part of the blood.

Keyhole limpet hemocyanin

Keyhole limpet hemocyanin from ''Megathura crenulata'' is used as

vaccine A vaccine is a biological Dosage form, preparation that provides active acquired immunity to a particular infectious disease, infectious or cancer, malignant disease. The safety and effectiveness of vaccines has been widely studied and verifi ...

carrier protein. Keyhole limpet hemocyanin (KLH) is a copper containing respiratory protein, similar to hemoglobin in humans. KLH is a large protein that acts as the hapten carrier part of the vaccine component, and is so far thought to be non-toxic. The major potential use of KLH is for bladder carcinoma by stimulating a specific immune response, but there are many other medical uses such as stress assessment, understanding inflammatory conditions, and treating drug addiction. Vaccines and other KLH uses are in the research or trial phases. A liter of blood from a keyhole limpet will produce 20 grams of protein, which can be worth as much as $100,000.Roudman, S
How mollusk blood could cure cancer.
''Popular Science'' 30 December 2011.

Description

Biology

Keyhole limpet hemocyanin

References

Further reading