Medical Treatment During Spaceflight
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It is inevitable that medical conditions of varying complexity, severity and emergency will occur during
spaceflight Spaceflight (or space flight) is an application of astronautics to fly objects, usually spacecraft, into or through outer space, either with or without humans on board. Most spaceflight is uncrewed and conducted mainly with spacecraft such ...
missions with human participants. Different levels of care are required depending on the problem, available resources and time required to return to Earth. All medical problems have the potential to affect the mission, but significant illnesses or trauma will result in a high probability of mission failure or loss of crew. As the distance that missions travel from Earth increases, more possible medical conditions and types of trauma will need to be evaluated. Return to Earth will be highly unlikely or very difficult depending on the distance traveled. Emergency health care will, and psychological support may, have to be self-administered and could possibly be completely autonomous. The most effective way to provide adequate support is to establish a thorough pre-flight health status assessment and develop a systematic approach to autonomous health care in space. For
NASA The National Aeronautics and Space Administration (NASA ) is an independent agencies of the United States government, independent agency of the federal government of the United States, US federal government responsible for the United States ...
, specific provisions and requirements for medical services during space missions are outlined i
NPD 8900.5B NASA Health and Medical Policy for Human Space ExplorationNPD 8900.1G Medical Operations Responsibilities in Support of Human Space Flight Programs
an
NASA-STD-3001 NASA Spaceflight Human Systems Standard - Volume 1, Crew Health


In flight


Non-emergencies

Most medical conditions that occur while in flight do not constitute a medical emergency and can be treated with medication, if available. Some documented non-emergency conditions that have occurred while in space include, Space Adaptation Sickness,
motion sickness Motion sickness occurs due to a difference between actual and expected motion. Symptoms commonly include nausea, vomiting, cold sweat, headache, dizziness, tiredness, loss of appetite, and increased salivation. Complications may rarely include ...
,
headache A headache, also known as cephalalgia, is the symptom of pain in the face, head, or neck. It can occur as a migraine, tension-type headache, or cluster headache. There is an increased risk of Depression (mood), depression in those with severe ...
,
sleeplessness Insomnia, also known as sleeplessness, is a sleep disorder where people have difficulty sleeping. They may have difficulty falling asleep, or staying asleep for as long as desired. Insomnia is typically followed by daytime sleepiness, low ene ...
,
back pain Back pain (Latin: ''dorsalgia'') is pain felt in the back. It may be classified as neck pain (cervical), middle back pain (thoracic), lower back pain (lumbar) or coccydynia (tailbone or sacral pain) based on the segment affected. The lumbar area ...
,
trauma Trauma most often refers to: *Psychological trauma, in psychology and psychiatric medicine, refers to severe mental and emotional injury caused by distressing events *Traumatic injury, sudden physical injury caused by an external force, which doe ...
,
burn A burn is an injury to skin, or other tissues, caused by heat, electricity, chemicals, friction, or ionizing radiation (such as sunburn, caused by ultraviolet radiation). Most burns are due to heat from hot fluids (called scalding), soli ...
s, dermatological conditions, musculoskeletal conditions,
respiratory illness Respiratory diseases, or lung diseases, are pathological conditions affecting the organs and tissues that make gas exchange difficult in air-breathing animals. They include conditions of the respiratory tract including the trachea, bronchi, bron ...
and
genitourinary The genitourinary system, or urogenital system, are the sex organs of the reproductive system and the organs of the urinary system. These are grouped together because of their proximity to each other, their common embryological origin and the us ...
problems. The use of medication relating to sleep loss and circadian rhythmicity is widespread amongst astronauts. According to an observational study of 79 early U.S. shuttle missions, hypnotic drugs accounted for 45% of all medication dispensed to astronauts in space.


Emergencies

Potential medical emergencies during space flight include
arrhythmia Arrhythmias, also known as cardiac arrhythmias, are irregularities in the cardiac cycle, heartbeat, including when it is too fast or too slow. Essentially, this is anything but normal sinus rhythm. A resting heart rate that is too fast – ab ...
s,
heart attack A myocardial infarction (MI), commonly known as a heart attack, occurs when Ischemia, blood flow decreases or stops in one of the coronary arteries of the heart, causing infarction (tissue death) to the heart muscle. The most common symptom ...
,
stroke Stroke is a medical condition in which poor cerebral circulation, blood flow to a part of the brain causes cell death. There are two main types of stroke: brain ischemia, ischemic, due to lack of blood flow, and intracranial hemorrhage, hemor ...
,
embolism An embolism is the lodging of an embolus, a blockage-causing piece of material, inside a blood vessel. The embolus may be a blood clot (thrombus), a fat globule (fat embolism), a bubble of air or other gas (air embolism, gas embolism), amniotic ...
, massive
hemorrhage Bleeding, hemorrhage, haemorrhage or blood loss, is blood escaping from the circulatory system from damaged blood vessels. Bleeding can occur internally, or externally either through a natural opening such as the mouth, nose, ear, urethra, ...
, emergencies related to
renal stone Kidney stone disease (known as nephrolithiasis, renal calculus disease, or urolithiasis) is a crystallopathy and occurs when there are too many minerals in the urine and not enough liquid or hydration. This imbalance causes tiny pieces of cry ...
formation,
infection An infection is the invasion of tissue (biology), tissues by pathogens, their multiplication, and the reaction of host (biology), host tissues to the infectious agent and the toxins they produce. An infectious disease, also known as a transmis ...
and thrombotic complications. To date, arrhythmias,
renal colic Renal colic (literally, kidney pain), also known as ureteric colic (literally, pain in the ureters), is characterized by severe abdominal pain that is spasmodic in nature. This pain is primarily caused by an obstruction of one or both ureters fr ...
,
venous thrombosis Venous thrombosis is the blockage of a vein caused by a thrombus (blood clot). A common form of venous thrombosis is deep vein thrombosis (DVT), when a blood clot forms in the deep veins. If a thrombus breaks off ( embolizes) and flows to the lu ...
, and infections have been documented during space flights. The documented arrhythmias were mostly mild abnormalities, but potentially serious arrhythmias have been reported. The manifestation of
coronary artery disease Coronary artery disease (CAD), also called coronary heart disease (CHD), or ischemic heart disease (IHD), is a type of cardiovascular disease, heart disease involving Ischemia, the reduction of blood flow to the cardiac muscle due to a build-up ...
has not been registered during any human space flight, but considering the risk of coronary events in older people and the increasing age of crew members, the possibility of complications during long-duration missions should not be ignored. Other medical emergencies that have been observed in space include rare but real cases of urological and dental emergencies. Additional consideration substantiates the risk of the inability to treat crew members on long-duration missions.


Radiation

Radiation In physics, radiation is the emission or transmission of energy in the form of waves or particles through space or a material medium. This includes: * ''electromagnetic radiation'' consisting of photons, such as radio waves, microwaves, infr ...
exposure may affect the general health of crew members and cause radiation specific pathological processes. Emergencies due to radiation exposure would most likely be catastrophic and mission ending.


Other risks

Other considerations for designing space medical care systems include exposure to toxic substances,
chemical burns A chemical burn occurs when living tissue is exposed to a corrosive substance (such as a strong acid, base or oxidizer) or a cytotoxic agent (such as mustard gas, lewisite or arsine). Chemical burns follow standard burn classification and may ca ...
, electrical burns and
trauma Trauma most often refers to: *Psychological trauma, in psychology and psychiatric medicine, refers to severe mental and emotional injury caused by distressing events *Traumatic injury, sudden physical injury caused by an external force, which doe ...
(on board and during EVA's). Exposure to a range of hazards including chemical substances, microbes, radiation and noise can be prevented or controlled by the application of effective astronautical hygiene practice. A 2006 Space Shuttle experiment found that ''
Salmonella typhimurium ''Salmonella enterica'' subsp. ''enterica'' is a subspecies of ''Salmonella enterica'', the rod-shaped, flagellated, aerobic, Gram-negative bacterium. Many of the pathogenic serovars of the ''S. enterica'' species are in this subspecies, includin ...
'', a bacterium that can cause
food poisoning Foodborne illness (also known as foodborne disease and food poisoning) is any illness resulting from the contamination of food by pathogenic bacteria, viruses, or parasites, as well as prions (the agents of mad cow disease), and toxins such ...
, became more virulent when cultivated in space. On April 29, 2013, scientists in Rensselaer Polytechnic Institute, funded by
NASA The National Aeronautics and Space Administration (NASA ) is an independent agencies of the United States government, independent agency of the federal government of the United States, US federal government responsible for the United States ...
, reported that, during
spaceflight Spaceflight (or space flight) is an application of astronautics to fly objects, usually spacecraft, into or through outer space, either with or without humans on board. Most spaceflight is uncrewed and conducted mainly with spacecraft such ...
on the
International Space Station The International Space Station (ISS) is a large space station that was Assembly of the International Space Station, assembled and is maintained in low Earth orbit by a collaboration of five space agencies and their contractors: NASA (United ...
,
microbes A microorganism, or microbe, is an organism of microscopic size, which may exist in its single-celled form or as a colony of cells. The possible existence of unseen microbial life was suspected from antiquity, with an early attestation in ...
seem to adapt to the
space environment Space environment is a branch of astronautics, aerospace engineering and space physics that seeks to understand and address conditions existing in space that affect the design and operation of spacecraft. A related subject, space weather, deals wit ...
in ways "not observed on Earth" and in ways that "can lead to increases in growth and
virulence Virulence is a pathogen's or microorganism's ability to cause damage to a host. In most cases, especially in animal systems, virulence refers to the degree of damage caused by a microbe to its host. The pathogenicity of an organism—its abili ...
". More recently, in 2017,
bacteria Bacteria (; : bacterium) are ubiquitous, mostly free-living organisms often consisting of one Cell (biology), biological cell. They constitute a large domain (biology), domain of Prokaryote, prokaryotic microorganisms. Typically a few micr ...
were found to be more resistant to
antibiotic An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting pathogenic bacteria, bacterial infections, and antibiotic medications are widely used in the therapy ...
s and to thrive in the near-weightlessness of space.
Microorganism A microorganism, or microbe, is an organism of microscopic scale, microscopic size, which may exist in its unicellular organism, single-celled form or as a Colony (biology)#Microbial colonies, colony of cells. The possible existence of unseen ...
s have been observed to survive the
vacuum A vacuum (: vacuums or vacua) is space devoid of matter. The word is derived from the Latin adjective (neuter ) meaning "vacant" or "void". An approximation to such vacuum is a region with a gaseous pressure much less than atmospheric pressur ...
of outer space.


On the ground

Ground-based incidences of illness encountered by individuals exposed to harsh environments (
Antarctic expedition This list of Antarctica expeditions is a chronological list of expeditions involving Antarctica. Although the existence of a southern continent had been hypothesized as early as the writings of Ptolemy in the 1st century AD, the South Pole was n ...
s, submarines and undersea habitats) could be considered as analogs of the space environment. These crews living and working in harsh environments have had medical emergencies such as
intracerebral hemorrhage Intracerebral hemorrhage (ICH), also known as hemorrhagic stroke, is a sudden bleeding into Intraparenchymal hemorrhage, the tissues of the brain (i.e. the parenchyma), into its Intraventricular hemorrhage, ventricles, or into both. An ICH is ...
,
stroke Stroke is a medical condition in which poor cerebral circulation, blood flow to a part of the brain causes cell death. There are two main types of stroke: brain ischemia, ischemic, due to lack of blood flow, and intracranial hemorrhage, hemor ...
, myocardial infarction (heart attack),
appendicitis Appendicitis is inflammation of the Appendix (anatomy), appendix. Symptoms commonly include right lower abdominal pain, nausea, vomiting, fever and anorexia (symptom), decreased appetite. However, approximately 40% of people do not have these t ...
and
bone fractures A bone fracture (abbreviated FRX or Fx, Fx, or #) is a medical condition in which there is a partial or complete break in the continuity of any bone in the body. In more severe cases, the bone may be broken into several fragments, known as a ''c ...
. Cases of cancer and psychiatric illness were also documented. Dental problems were the most common emergency during submarine and Antarctic expeditions and were a cause for transfer in the U.S. Polaris submarine program. Risk estimates made from data provided by analog studies have certain limitations for long duration missions. Unique problems that are inherent to the space environment include the effects of radiation, exposure and physiological adaptation to low gravity. Cardiovascular events are of particular interest for long duration space missions and other harsh environments. To use United States Air Force (USAF) aviators as an example, even though they undergo a very rigorous health screening, the first manifestation of CAD (coronary artery disease) is a cardiac event. Even though the health assessment for an astronaut is more extensive than USAF aviators, data collected from USAF aviators are applicable to the astronaut corps and emphasizes the risk of occurrence of sudden death or heart attack in space despite thorough screening.
Appendicitis Appendicitis is inflammation of the Appendix (anatomy), appendix. Symptoms commonly include right lower abdominal pain, nausea, vomiting, fever and anorexia (symptom), decreased appetite. However, approximately 40% of people do not have these t ...
is the most common general surgical condition for the submarine program and has been the cause of one death on an Antarctic expedition. Other serious conditions reported in the submarine program and Antarctic expeditions include
traumatic amputation Amputation is the removal of a limb or other body part by trauma, medical illness, or surgery. As a surgical measure, it is used to control pain or a disease process in the affected limb, such as malignancy or gangrene. In some cases, it is ...
s,
fractures Fracture is the appearance of a crack or complete separation of an object or material into two or more pieces under the action of stress (mechanics), stress. The fracture of a solid usually occurs due to the development of certain displacemen ...
,
dislocations In materials science, a dislocation or Taylor's dislocation is a linear crystallographic defect or irregularity within a crystal structure that contains an abrupt change in the arrangement of atoms. The movement of dislocations allow atoms to sli ...
, depression and
anxiety Anxiety is an emotion characterised by an unpleasant state of inner wikt:turmoil, turmoil and includes feelings of dread over Anticipation, anticipated events. Anxiety is different from fear in that fear is defined as the emotional response ...
.


Exploration scenarios

These documented conditions serve as a basis for the Exploration medical list. This list is currently under development and will assist in planning research and development activities. A medical support system is being developed to ensure that adequate medical care can be administered autonomously or with support from ground crews on Earth.


Computer based simulators

Th
Integrated Medical Model (IMM)
a computer based simulator that quantifies the probability and consequences of medical risks, is currently being developed.


See also

*
Astronautical hygiene Astronautical hygiene evaluates, and mitigates, hazards and health risks to those working in low-gravity environments. The discipline of astronautical hygiene includes such topics as the use and maintenance of life support systems, the risks of th ...
*
Bioastronautics Bioastronautics is a specialty area of biological and astronautical research which encompasses numerous aspects of biological, behavioral, and medical concern governing humans and other living organisms in outer space; and includes the design o ...
*
Effect of spaceflight on the human body The effects of spaceflight on the human body are complex and largely harmful over both short and long term. Significant adverse effects of long-term weightlessness include muscle atrophy and deterioration of the skeleton ( spaceflight osteopeni ...
*
Human analog missions Human analog missions are activities undertaken on Earth in various environments to simulate aspects of human missions to other worlds, including the Moon, asteroids, and Mars. These remote field tests are performed in locations that are identifie ...
* Illness and injuries during spaceflight *
Space adaptation syndrome Space adaptation syndrome (SAS) or space sickness is a condition experienced by as many as half of all space travelers during their adaptation to weightlessness once in orbit. It is the opposite of terrestrial motion sickness since it occurs whe ...
*
Space colonization Space colonization (or extraterrestrial colonization) is the human settlement, settlement or colonization of outer space and astronomical bodies. The concept in its broad sense has been applied to any permanent human presence in space, such ...
*
Space exposure The effects of spaceflight on the human body are complex and largely harmful over both short and long term. Significant adverse effects of long-term weightlessness include muscle atrophy and osteoporosis, deterioration of the Human skeleton, ske ...
* *
Space survival The effects of spaceflight on the human body are complex and largely harmful over both short and long term. Significant adverse effects of long-term weightlessness include muscle atrophy and deterioration of the skeleton (spaceflight osteopenia ...


References


External links


Scott Dulchavsky trains astronauts to diagnosis their injuries in space

Musculoskeletal injuries and minor trauma in space: incidence and injury mechanisms in U.S. astronauts


* ttp://www.upi.com/Science_News/2012/02/06/Virtual-display-could-diagnose-illness-in-space/UPI-96181328577298 Virtual display could diagnose illness in space
Prophylactic surgery prior to extended-duration space flight: Is the benefit worth the risk?
{{Space medicine Space medicine