Matthew Porteus
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Matthew Hebden Porteus is Sutardja Chuk Professor of Definitive and Curative Medicine at
Stanford University Leland Stanford Junior University, commonly referred to as Stanford University, is a Private university, private research university in Stanford, California, United States. It was founded in 1885 by railroad magnate Leland Stanford (the eighth ...
. In 2003, as a postdoctoral fellow in
David Baltimore David Baltimore (born March 7, 1938) is an American biologist, university administrator, and 1975 Nobel Prize in Physiology or Medicine, Nobel laureate in Physiology or Medicine. He is a professor of biology at the California Institute of Tech ...
's lab at the
California Institute of Technology The California Institute of Technology (branded as Caltech) is a private research university in Pasadena, California, United States. The university is responsible for many modern scientific advancements and is among a small group of institutes ...
, Porteus was the first to demonstrate precise
gene editing Gene editing may refer to: *Genetic engineering of any organism by genome editing. Gene editing is the emerging molecular biology technique which makes very specific targeted changes by insertion, deletion or substitution of genetic material in an ...
in human cells using
chimeric nuclease Chimeric nucleases are an example of engineered proteins which must comprise a DNA-binding domain to give sequence specificity and a nuclease domain for DNA cleavage. DNA-binding domains DNA-binding domains including the basic helix-loop-heli ...
s. He graduated
magna cum laude Latin honors are a system of Latin phrases used in some colleges and universities to indicate the level of distinction with which an academic degree has been earned. The system is primarily used in the United States. It is also used in some Sout ...
from
Harvard University Harvard University is a Private university, private Ivy League research university in Cambridge, Massachusetts, United States. Founded in 1636 and named for its first benefactor, the History of the Puritans in North America, Puritan clergyma ...
and completed his MD and PhD at
Stanford University Leland Stanford Junior University, commonly referred to as Stanford University, is a Private university, private research university in Stanford, California, United States. It was founded in 1885 by railroad magnate Leland Stanford (the eighth ...
. For his post-doctoral work he trained with David Baltimore at
MIT The Massachusetts Institute of Technology (MIT) is a private research university in Cambridge, Massachusetts, United States. Established in 1861, MIT has played a significant role in the development of many areas of modern technology and sc ...
and
Caltech The California Institute of Technology (branded as Caltech) is a private university, private research university in Pasadena, California, United States. The university is responsible for many modern scientific advancements and is among a small g ...
. He is a scientific founder of
CRISPR Therapeutics CRISPR Therapeutics AG is a Swiss–American biotechnology company headquartered in Zug, Switzerland. The company does business as CRISPR Therapeutics, Inc. in the United States. It was one of the first companies formed to utilize the CRISPR gen ...
and an academic founder of Graphite Bio. He has an
h-index The ''h''-index is an author-level metric that measures both the productivity and citation impact of the publications, initially used for an individual scientist or scholar. The ''h''-index correlates with success indicators such as winning t ...
of 69 according to
Google Scholar Google Scholar is a freely accessible web search engine that indexes the full text or metadata of Academic publishing, scholarly literature across an array of publishing formats and disciplines. Released in Beta release, beta in November 2004, th ...
.


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* Year of birth missing (living people) Living people Harvard University alumni Stanford University alumni University of Texas Southwestern Medical Center faculty Stanford University faculty {{Scientist-stub