Matidia can refer to:
* Salonia Matidia, niece of the Roman Emperor Trajan and mother-in-law of Hadrian, posthumously deified under the name ''diva Matidia''
* Matidia Minor or Mindia Matidia, the second daughter of Salonia Matidia, who gave her name to the Italian village of [Matigge
* Matidia (spider), ''Matidia'' (spider), a genus of spiders
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