Mason Sones
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F. Mason Sones, Jr. (October 28, 1918 – August 28, 1985) was an American physician whose pioneering work in
cardiac catheterization Cardiac catheterization (heart cath) is the insertion of a catheter into a heart chamber, chamber or Blood vessel, vessel of the heart. This is done both for diagnostic and interventional purposes. A common example of cardiac catheterization is c ...
was instrumental in the development of both
coronary artery bypass surgery Coronary artery bypass surgery, also known as coronary artery bypass graft (CABG, pronounced "cabbage"), is a surgical procedure to treat coronary artery disease (CAD), the buildup of plaques in the arteries of the heart. It can relieve chest ...
and
interventional cardiology Interventional cardiology is a branch of cardiology that deals specifically with the catheter based treatment of structural heart diseases. Andreas Gruentzig is considered the father of interventional cardiology after the development of angioplast ...
.


Early life and career

Sones was born in Noxapater,
Mississippi Mississippi ( ) is a U.S. state, state in the Southeastern United States, Southeastern and Deep South regions of the United States. It borders Tennessee to the north, Alabama to the east, the Gulf of Mexico to the south, Louisiana to the s ...
Westaby, p. 214 to Frank Mason and Myrtle (Bryan) Sones. He graduated from
Western Maryland College McDaniel College is a private college in Westminster, Maryland, United States. Established in 1867, it was known as Western Maryland College until 2002 when it was renamed McDaniel College in honor of an alumnus who gave a lifetime of service to ...
(now McDaniel College) in 1940 and received his M.D. from the
University of Maryland School of Medicine The University of Maryland School of Medicine (abbreviated UMSOM), located in Baltimore City, Maryland, U.S., is the medical school of the University of Maryland, Baltimore and is affiliated with the University of Maryland Medical Center and ...
in 1943. In 1942, Sones married Geraldine Newton. The couple had four children, Frank Mason III, Geraldine Patricia, Steven, and David. From 1944 to 1946, he served in the
United States Army Air Corps The United States Army Air Corps (USAAC) was the aerial warfare service component of the United States Army between 1926 and 1941. After World War I, as early aviation became an increasingly important part of modern warfare, a philosophical ri ...
in the Pacific and would later serve as a national consultant to the Air Force. Sones served as an
intern An internship is a period of work experience offered by an organization for a limited period of time. Once confined to medical graduates, internship is used to practice for a wide range of placements in businesses, non-profit organizations and g ...
at University Hospital in
Baltimore Baltimore is the most populous city in the U.S. state of Maryland. With a population of 585,708 at the 2020 census and estimated at 568,271 in 2024, it is the 30th-most populous U.S. city. The Baltimore metropolitan area is the 20th-large ...
and was a
Resident Resident may refer to: People and functions * Resident minister, a representative of a government in a foreign country * Resident (medicine), a stage of postgraduate medical training * Resident (pharmacy), a stage of postgraduate pharmaceut ...
at
Henry Ford Hospital Henry Ford Hospital (HFH) is an 877-bed tertiary care hospital, education and research complex at the western edge of the New Center, Detroit, New Center area in Detroit, Michigan. The flagship facility for the Henry Ford Health System, it wa ...
in
Detroit Detroit ( , ) is the List of municipalities in Michigan, most populous city in the U.S. state of Michigan. It is situated on the bank of the Detroit River across from Windsor, Ontario. It had a population of 639,111 at the 2020 United State ...
before joining the
Cleveland Clinic Foundation Cleveland Clinic is an American nonprofit academic medical center based in Cleveland, Ohio. Owned and operated by the Cleveland Clinic Foundation, an Ohio nonprofit corporation, Cleveland Clinic was founded in 1921 by a group of faculty and alu ...
in 1950.


Discovery of coronary angiography

While at Henry Ford, Sones had learned the techniques of cardiac catheterization and his first appointment at the Cleveland Clinic was as head of
Pediatric Pediatrics (American English) also spelled paediatrics (British English), is the branch of medicine that involves the medical care of infants, children, adolescents, and young adults. In the United Kingdom, pediatrics covers many of their youth ...
Cardiology. On October 30, 1958, while working in the Cardiac Laboratory on a 26-year-old patient with
rheumatic heart disease Valvular heart disease is any cardiovascular disease process involving one or more of the four valves of the heart (the aortic and mitral valves on the left side of heart and the pulmonic and tricuspid valves on the right side of heart). The ...
, Sones was performing a procedure in which
contrast dye Radiocontrast agents are substances used to enhance the visibility of internal structures in X-ray-based imaging techniques such as computed tomography (contrast CT), projectional radiography, and fluoroscopy. Radiocontrast agents are typically iod ...
was to be injected into the man's
aorta The aorta ( ; : aortas or aortae) is the main and largest artery in the human body, originating from the Ventricle (heart), left ventricle of the heart, branching upwards immediately after, and extending down to the abdomen, where it splits at ...
. Just before the dye injection, Sones noticed that the catheter tip had inadvertently entered the man's
right coronary artery In the coronary circulation, blood supply of the heart, the right coronary artery (RCA) is an artery originating above the right cusp of the aortic valve, at the Aortic sinus, right aortic sinus in the heart. It travels down the right coronary su ...
. Sones asked that the catheter be withdrawn, but before that could be accomplished, a large amount of dye was injected directly into the artery. Sones expected the man's heart to go into
fibrillation Fibrillation is the rapid, irregular, and unsynchronized contraction of muscle fibers. An important occurrence is with regard to the heart. Cardiology There are two major classes of cardiac fibrillation: atrial fibrillation and ventricular fib ...
and prepared to do an emergency open chest massage. But instead of fibrillating, the man's heart went into
asystole Asystole (New Latin, from Greek privative a "not, without" + ''systolē'' "contraction") is the absence of ventricular contractions in the context of a lethal heart arrhythmia (in contrast to an induced asystole on a cooled patient on a heart-lun ...
, and Sones shouted at him to cough, which successfully restarted the heart beating. From this experience, Sones realized that smaller amounts of contrast dye ''could'' safely be injected directly into coronary arteries, giving
cardiologists Cardiology () is the study of the heart. Cardiology is a branch of medicine that deals with disorders of the heart and the cardiovascular system. The field includes medical diagnosis and treatment of congenital heart defects, coronary artery di ...
accurate pictures of arterial blockages for the first time. Sones subsequently studied video engineering, dye chemistry, and optical image amplification to perfect the procedure. In 1967, Sones' Cleveland Clinic colleague,
René Favaloro René Gerónimo Favaloro (July 12, 1923 – July 29, 2000) was an Argentine Cardiothoracic surgery, cardiac surgeon and Teacher, educator best known for his pioneering work on coronary artery bypass surgery using the great saphenous vein. Ear ...
, performed the world's first
coronary bypass surgery Coronary artery bypass surgery, also known as coronary artery bypass graft (CABG, pronounced "cabbage"), is a surgical procedure to treat coronary artery disease (CAD), the buildup of plaques in the arteries of the heart. It can relieve chest p ...
. Favaloro called Sones "the most important contributor to modern cardiology" and said that without his work, "all our efforts in myocardial revascularization would have been fruitless."


Later career and awards

Sones was the Director of the Cleveland Clinic Department of Cardiovascular Disease from 1966 to 1975, and later served as senior physician of the Department of Cardiology. Sones was honored with numerous awards during his career, including the
American Medical Association The American Medical Association (AMA) is an American professional association and lobbying group of physicians and medical students. This medical association was founded in 1847 and is headquartered in Chicago, Illinois. Membership was 271,660 ...
's 1978 Scientific Achievement Award and the
Gairdner Foundation International Award The Canada Gairdner International Award is given annually by the Gairdner Foundation at a special dinner to five individuals for outstanding discoveries or contributions to medical science. Receipt of the Gairdner is traditionally considered a ...
in 1969. In 1973 he was awarded the
Texas Heart Institute The Texas Heart Institute, founded by Denton Cooley in 1962, is a nonprofit organization dedicated to reducing the devastating toll of cardiovascular disease through innovative and progressive programs in research, education and improved patient ...
's Ray C. Fish Award. He was a leading participant in the founding of the Society for Cardiac Angiography (now known as the Society for Cardiovascular Angiography and Interventions) and was its first president. Sones died of lung cancer on August 28, 1985, in Cleveland, at the age of 66, and was buried in Chagrin Falls, Ohio - Evergreen Cemetery.


References


Sources

* * * {{DEFAULTSORT:Sones, F. Mason 1918 births 1985 deaths American cardiac surgeons University of Maryland, Baltimore alumni Recipients of the Lasker–DeBakey Clinical Medical Research Award People from Winston County, Mississippi Cleveland Clinic people 20th-century American surgeons Western Maryland College alumni