Maryam Shanechi
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Maryam M. Shanechi is an Iran-born American neuroengineer. She studies ways of decoding the brain's activity to control brain-machine interfaces. She was honored as one of
MIT Technology Review ''MIT Technology Review'' is a bimonthly magazine wholly owned by the Massachusetts Institute of Technology. It was founded in 1899 as ''The Technology Review'', and was re-launched without "''The''" in its name on April 23, 1998, under then pu ...
's Innovators under 35 in 2014, one of the
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10 scientists to watch in 2019, and a National Finalist for the
Blavatnik Awards for Young Scientists Blavatnik Awards for Young Scientists was established in 2007 through a partnership between the Blavatnik Family Foundation, headed by Leonard Blavatnik (Russian: Леонид Валентинович Блаватник), chairman of Access Indu ...
in 2023. She is Dean's Professor in Electrical and Computer Engineering, Computer Science, and Biomedical Engineering at the USC Viterbi School of Engineering, and a member of the Neuroscience Graduate Program at the
University of Southern California The University of Southern California (USC, SC, or Southern Cal) is a Private university, private research university in Los Angeles, California, United States. Founded in 1880 by Robert M. Widney, it is the oldest private research university in ...
.


Early life and career

Shanechi was born in
Iran Iran, officially the Islamic Republic of Iran (IRI) and also known as Persia, is a country in West Asia. It borders Iraq to the west, Turkey, Azerbaijan, and Armenia to the northwest, the Caspian Sea to the north, Turkmenistan to the nort ...
and moved to Canada with her family when she was 16. She received her bachelor's degree in engineering from the
University of Toronto The University of Toronto (UToronto or U of T) is a public university, public research university whose main campus is located on the grounds that surround Queen's Park (Toronto), Queen's Park in Toronto, Ontario, Canada. It was founded by ...
in 2004. She then moved to
MIT The Massachusetts Institute of Technology (MIT) is a private research university in Cambridge, Massachusetts, United States. Established in 1861, MIT has played a significant role in the development of many areas of modern technology and sc ...
, where she completed her master's degree in electrical engineering and computer science in 2006 and her PhD in 2011. She completed a postdoc at Harvard Medical School before moving to the
University of California, Berkeley The University of California, Berkeley (UC Berkeley, Berkeley, Cal, or California), is a Public university, public Land-grant university, land-grant research university in Berkeley, California, United States. Founded in 1868 and named after t ...
, in 2012. She held a faculty position at Cornell University, before moving to the
University of Southern California The University of Southern California (USC, SC, or Southern Cal) is a Private university, private research university in Los Angeles, California, United States. Founded in 1880 by Robert M. Widney, it is the oldest private research university in ...
, where she is currently Dean's Professor within the USC Viterbi School of Engineering.


Research

While pursuing her graduate degree at MIT, Shanechi became interested in decoding the brain, the idea of reading out the original meaning from brain signals. She developed an algorithm to determine where a monkey wanted to point the cursor on a screen based on the animal's brain activity. She later improved upon her work by including high-rate decoding, meaning the decoding happened over a few milliseconds, rather than every 100 milliseconds, which is the standard for traditional methods. More recently, th
Shanechi Lab
has developed novel methods that can dissociate those dynamics in neural activity that are most predictive of behavior and can significantly improve decoding. Her lab has also developed methods that can simultaneously use multiple spatiotemporal scales of neural measurements to model their relationships and improve decoding. In 2013, she developed a brain decoding method that could help automatically control the amount of
anesthesia Anesthesia (American English) or anaesthesia (British English) is a state of controlled, temporary loss of sensation or awareness that is induced for medical or veterinary purposes. It may include some or all of analgesia (relief from or prev ...
that is to be administered to a patient. Her team, which included colleagues from
Massachusetts General Hospital Massachusetts General Hospital (Mass General or MGH) is a teaching hospital located in the West End neighborhood of Boston, Massachusetts. It is the original and largest clinical education and research facility of Harvard Medical School/Harvar ...
and
Massachusetts Institute of Technology The Massachusetts Institute of Technology (MIT) is a Private university, private research university in Cambridge, Massachusetts, United States. Established in 1861, MIT has played a significant role in the development of many areas of moder ...
was able to control the depth of the medically-induced coma in rodents automatically based on their brain activity. Shanechi is also interested in the application of neural decoding algorithms to psychiatric disorders, such as
PTSD Post-traumatic stress disorder (PTSD) is a mental disorder that develops from experiencing a traumatic event, such as sexual assault, domestic violence, child abuse, warfare and its associated traumas, natural disaster, traffic collision, ...
and depression. Her research team developed a method to decipher the mood of a person from their brain activity. They measured the brain activity of seven patients who had electrodes implanted in their brain to monitor
epilepsy Epilepsy is a group of Non-communicable disease, non-communicable Neurological disorder, neurological disorders characterized by a tendency for recurrent, unprovoked Seizure, seizures. A seizure is a sudden burst of abnormal electrical activit ...
. The patients answered questions about their mood while the electrodes were implanted. Using the data about the mood and the brain activity, Shanechi's lab was able to match the two together and decipher which brain activity was related to which mood. The paper on this work was awarded the 3rd prize in the International BCI Awards. Her lab has also developed a stochastic stimulation and modeling approach that can predict the response of multi-regional brain networks implicated in neuropsychiatric disorders to ongoing deep brain stimulation (DBS). In the future, Shanechi wants to develop these techniques in order to stimulate the brain automatically when a change in mood is detected.


Awards

*
NIH Director's New Innovator Award National Institutes of Health Director's New Innovator Award is a research initiative first announced in 2007 designed to supports exceptionally creative, early-career investigators who propose innovative, high-impact projects. The focus is specif ...
, 2020 *
Science News ''Science News'' (''SN'') is an American monthly magazine devoted to articles about new scientific and technical developments, typically gleaned from recent scientific and technical journals. The periodical has been described as having a scop ...
10 Scientists to Watch, 2019 *
Popular Science Popular science (also called pop-science or popsci) is an interpretation of science intended for a general audience. While science journalism focuses on recent scientific developments, popular science is more broad ranging. It may be written ...
Brilliant 10, 2015 *
MIT Technology Review ''MIT Technology Review'' is a bimonthly magazine wholly owned by the Massachusetts Institute of Technology. It was founded in 1899 as ''The Technology Review'', and was re-launched without "''The''" in its name on April 23, 1998, under then pu ...
Innovators Under 35, 2014 * NSF CAREER Award, 2015 *
Office of Naval Research The Office of Naval Research (ONR) is an organization within the United States Department of the Navy responsible for the science and technology programs of the U.S. Navy and Marine Corps. Established by Congress in 1946, its mission is to plan ...
Young Investigator Award, 2019 *
American Society for Engineering Education American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, ...
(ASEE) Curtis W. McGraw Research Award, 2021 *Multidisciplinary University Research Initiative (MURI) Award, 2016 *Mid-Career Achievement Award, University of Toronto Engineering, 2019
One Mind Rising Star Award
2022


Selected publications

Shanechi's publications include: * * * * * * * *


References

{{DEFAULTSORT:Shanechi, Maryam 1981 births Living people American neuroscientists American women neuroscientists University of Southern California faculty Iranian emigrants to the United States University of Toronto alumni Massachusetts Institute of Technology alumni American electrical engineers American women engineers