Mary Letitia Caldwell
   HOME

TheInfoList



OR:

Mary Letitia Caldwell (December 18, 1890 – July 1, 1972) was an American chemist. She was an instructor at Western College teaching chemistry. Mary was in a wheelchair due to muscular disability. Most of her work centered on
amylase An amylase () is an enzyme that catalysis, catalyses the hydrolysis of starch (Latin ') into sugars. Amylase is present in the saliva of humans and some other mammals, where it begins the chemical process of digestion. Foods that contain large ...
, a
starch Starch or amylum is a polymeric carbohydrate consisting of numerous glucose units joined by glycosidic bonds. This polysaccharide is produced by most green plants for energy storage. Worldwide, it is the most common carbohydrate in human diet ...
enzyme An enzyme () is a protein that acts as a biological catalyst by accelerating chemical reactions. The molecules upon which enzymes may act are called substrate (chemistry), substrates, and the enzyme converts the substrates into different mol ...
, most notably finding a method for purifying crystalline porcine pancreatic amylase. She spent sixty years doing this.


Early life and education

Caldwell was born in Bogota, Colombia, to American
missionaries A missionary is a member of a religious group who is sent into an area in order to promote its faith or provide services to people, such as education, literacy, social justice, health care, and economic development.Thomas Hale 'On Being a Miss ...
. She earned her bachelor's degree from the
Western College for Women Western College for Women, known at other times as Western Female Seminary and simply Western College, was a women's and later coed liberal arts college in Oxford, Ohio, between 1855 and 1974. Initially a seminary, it was the host of orientat ...
in 1913 and taught at the school until 1918. She earned her
M.A. A Master of Arts ( or ''Artium Magister''; abbreviated MA or AM) is the holder of a master's degree awarded by universities in many countries. The degree is usually contrasted with that of Master of Science. Those admitted to the degree have ...
and
Ph.D. A Doctor of Philosophy (PhD, DPhil; or ) is a terminal degree that usually denotes the highest level of academic achievement in a given discipline and is awarded following a course of graduate study and original research. The name of the deg ...
from
Columbia University Columbia University in the City of New York, commonly referred to as Columbia University, is a Private university, private Ivy League research university in New York City. Established in 1754 as King's College on the grounds of Trinity Churc ...
in 1919 and 1921. She had a progressive muscular disorder which made her reliant on a wheelchair for life. She came from a family of five siblings, all of whom valued higher education. She then became the first woman instructor in the chemistry department at Columbia University. In 1951 she retired from teaching and began her studies in enzymes, specifically amylase.


Career

After graduating from graduate school at Columbia University, Caldwell became the first Chemistry professor at Columbia University from 1948 to 1949. She became the only female member of the senior faculty in the chemistry department, becoming the first woman to attain the rank of assistant professor at Columbia. She attained the rank of full professor in 1948. Caldwell had a progressive muscular disability, and began using a wheelchair by 1960. Despite this, her 9th floor office at her research facility, Chandler Hall, never changed. In 1960 she received the
Garvan Medal Garvan may refer to: People * Francis Patrick Garvan (1875–1937), American lawyer, president of the Chemical Foundation * Frank Garvan (born 1955), Australian mathematician * Genevieve Garvan Brady (1880–1938), American philanthropist and Papa ...
from the American Chemical Society, an honor awarded annually to a US female chemist. During her time as a chemist, Caldwell did research on a type of enzyme called amylase. She spent a lot of her time trying to purify enzymes because she was not satisfied with the commercial material. She attempted to find a more pure form of amylase and she was able to develop a method for isolating crystalline pancreatic enzymes.


Awards and accomplishments

After receiving her M.S. and Ph.D. at Columbia University in 1919 and 1921, respectively, Caldwell was hired as an instructor in 1922. She eventually became the first female professor of chemistry in 1948, and the only female senior faculty member of the chemistry department at Columbia University at the time. In 1960, Caldwell was awarded the Garvan Medal by the American Chemistry Society for her research on amylase. The Garvan Medal specifically recognizes women who have made a significant contribution to the field of Chemistry. Caldwell developed a method to isolate crystalline pancreatic enzymes that is now used by laboratories all throughout America and Europe.


References


Further reading


Proceedings of the Thirty-Seventh Annual Meeting of The American Institute of Nutrition
* *


External links

* {{DEFAULTSORT:Caldwell, Mary Letitia 1890 births 1972 deaths Western College for Women alumni Columbia University alumni Columbia University faculty Recipients of the Garvan–Olin Medal American women chemists 20th-century American women scientists 20th-century American chemists 20th-century American women academics