Martin Kulldorff
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Martin Kulldorff (born 1962) is a Swedish biostatistician. He was a professor of medicine at
Harvard Medical School Harvard Medical School (HMS) is the medical school of Harvard University and is located in the Longwood Medical and Academic Area, Longwood Medical Area in Boston, Massachusetts. Founded in 1782, HMS is the third oldest medical school in the Un ...
from 2003 until his dismissal in 2024. He is a member of the US
Food and Drug Administration The United States Food and Drug Administration (FDA or US FDA) is a List of United States federal agencies, federal agency of the United States Department of Health and Human Services, Department of Health and Human Services. The FDA is respo ...
's Drug Safety and Risk Management Advisory Committee and a former member of the Vaccine Safety Subgroup of the
Advisory Committee on Immunization Practices The Advisory Committee on Immunization Practices (ACIP) is a National Immunization Technical Advisory Group, committee within the United States Centers for Disease Control and Prevention (CDC) that provides advice and guidance on effective control ...
at the
Centers for Disease Control and Prevention The Centers for Disease Control and Prevention (CDC) is the National public health institutes, national public health agency of the United States. It is a Federal agencies of the United States, United States federal agency under the United S ...
. In 2020, Kulldorff was a co-author of the Great Barrington Declaration, which advocated lifting
COVID-19 Coronavirus disease 2019 (COVID-19) is a contagious disease caused by the coronavirus SARS-CoV-2. In January 2020, the disease spread worldwide, resulting in the COVID-19 pandemic. The symptoms of COVID‑19 can vary but often include fever ...
restrictions on lower-risk groups to develop herd immunity through infection before vaccines became available, while promoting the fringe notion that vulnerable people could be simultaneously protected from the virus. The declaration was widely rejected, and was criticized as being unethical and infeasible by
Tedros Adhanom Ghebreyesus Tedros Adhanom Ghebreyesus (, sometimes spelled ; born 3 March 1965) is an Ethiopian public health official, researcher, diplomat, and the DGWHO, Director-General of the World Health Organization since 2017. He is the first African to become W ...
, the director-general of the
World Health Organization The World Health Organization (WHO) is a list of specialized agencies of the United Nations, specialized agency of the United Nations which coordinates responses to international public health issues and emergencies. It is headquartered in Gen ...
. During the pandemic, Kulldorff opposed disease control measures such as vaccination of children, lockdowns,
contact tracing In public health, contact tracing is the process of identifying people who may have been exposed to an infected person ("contacts") and subsequent collection of further data to assess transmission. By tracing the contacts of infected individua ...
, and mask mandates.


Early life and education

Kulldorff was born in
Lund Lund (, ;"Lund"
(US) and
) is a city in the provinces of Sweden, province of Scania, southern Swed ...
, Sweden, in 1962, the son of Barbro and Gunnar Kulldorff. He grew up in
Umeå Umeå ( , , , locally ; ; ; ; ) is a city in northeast Sweden. It is the seat of Umeå Municipality and the capital of Västerbotten County. Situated on the Ume River, Umeå is the largest Urban areas in Sweden, locality in Norrland and the t ...
and received a BSc in
mathematical statistics Mathematical statistics is the application of probability theory and other mathematical concepts to statistics, as opposed to techniques for collecting statistical data. Specific mathematical techniques that are commonly used in statistics inc ...
from Umeå University in 1984. He moved to the United States for his postgraduate studies as a Fulbright fellow, obtaining a
doctorate A doctorate (from Latin ''doctor'', meaning "teacher") or doctoral degree is a postgraduate academic degree awarded by universities and some other educational institutions, derived from the ancient formalism '' licentia docendi'' ("licence to teach ...
in
operations research Operations research () (U.S. Air Force Specialty Code: Operations Analysis), often shortened to the initialism OR, is a branch of applied mathematics that deals with the development and application of analytical methods to improve management and ...
from
Cornell University Cornell University is a Private university, private Ivy League research university based in Ithaca, New York, United States. The university was co-founded by American philanthropist Ezra Cornell and historian and educator Andrew Dickson W ...
in 1989. His doctoral thesis, titled ''Optimal Control of Favorable Games with a Time Limit'', was written under the direction of David Clay Heath.


Career

Kulldorff was an associate professor at the Department of Community Medicine at the
University of Connecticut The University of Connecticut (UConn) is a public land-grant research university system with its main campus in Storrs, Connecticut, United States. It was founded in 1881 as the Storrs Agricultural School, named after two benefactors. In 1893, ...
for five years and an associate professor at the Department of Statistics at
Uppsala University Uppsala University (UU) () is a public university, public research university in Uppsala, Sweden. Founded in 1477, it is the List of universities in Sweden, oldest university in Sweden and the Nordic countries still in operation. Initially fou ...
for six years. He has also worked as a scientist at the National Institutes of Health in the US. From 2003 to 2021 he was a professor of medicine at
Harvard Medical School Harvard Medical School (HMS) is the medical school of Harvard University and is located in the Longwood Medical and Academic Area, Longwood Medical Area in Boston, Massachusetts. Founded in 1782, HMS is the third oldest medical school in the Un ...
, and from 2015 to 2021 he was also a biostatistician at the
Brigham and Women's Hospital Brigham and Women's Hospital (BWH or The Brigham) is a teaching hospital of Harvard Medical School and the largest hospital in the Longwood Medical Area in Boston, Massachusetts. Along with Massachusetts General Hospital, it is one of the two ...
. Kulldorff developed
SaTScan SaTScan is a software tool that employs scan statistics for the spatial and temporal analysis of clusters of events. The software is trademarked by Martin Kulldorff, and was designed originally for public health and epidemiology to identify cluste ...
, a free software program used for geographical and hospital disease surveillance which is widely used, as well as a TreeScan software program for data mining. He is the co-developer of the R-Sequential software program for exact sequential analysis. He developed the statistical and epidemiological methods that are used in the software. These methods include spatial and space-time scan statistics, the tree-based
scan statistics In statistics, a scan statistic or window statistic is a problem relating to the clustering of randomly positioned points. An example of a typical problem is the maximum size of a cluster of points on a line or the longest series of successes record ...
and various sequential analysis methods. He helped develop and implement statistical methods used by the
Vaccine Safety Datalink The Vaccine Safety Datalink Project (VSD) was established in 1990 by the United States Centers for Disease Control and Prevention (CDC) to study the adverse effects of vaccines. Four large health maintenance organizations, including Kaiser Perm ...
(VSD) project that the
CDC The Centers for Disease Control and Prevention (CDC) is the national public health agency of the United States. It is a United States federal agency under the Department of Health and Human Services (HHS), and is headquartered in Atlanta, ...
uses, among other tools, to discover and evaluate vaccine health and safety risks. During the
COVID-19 pandemic The COVID-19 pandemic (also known as the coronavirus pandemic and COVID pandemic), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), began with an disease outbreak, outbreak of COVID-19 in Wuhan, China, in December ...
, Kulldorff advised Florida governor
Ron DeSantis Ronald Dion DeSantis (; born September 14, 1978) is an American politician, attorney, and former United States Navy, naval officer serving as the 46th List of governors of Florida, governor of Florida since 2019. A member of the Republican Pa ...
on health policy. In a September 2020 meeting he advocated aiming for herd immunity by not inhibiting the virus, saying that young people could "live normal life" until it had been reached, at which point older people could live more normal lives too. In 2021, Kulldorff was named a senior scientific director at the Brownstone Institute, a right-wing think tank launched by Jeffrey Tucker that publishes articles challenging various measures against COVID-19, presenting research supporting authors' opinions, and discussing alternative measures. Jay Bhattacharya and Sunetra Gupta, his co-authors on the Great Barrington Declaration, also have had roles there. Tucker is the former editorial director of the
American Institute for Economic Research The American Institute for Economic Research (AIER) is a classical liberal think tank located in Great Barrington, Massachusetts. It was founded in 1933 by Edward C. Harwood, an economist and investment advisor, and is a 501(c)(3) nonprofit. ...
(AIER), where the declaration was signed. In December 2021, Kulldorff became one of the first three fellows, along with Bhattacharya and Scott Atlas, at the Academy for Science and Freedom, a program of the private, conservative Hillsdale College, a liberal arts school. In March 2024, Kulldorff announced that Harvard had dismissed him. Kulldorff had refused a COVID vaccination that was required by the hospital through which Harvard Medical School faculty are employed. In 2025 Kulldorff, along with Jay Bhattacharya and others, founded the '' Journal of the Academy of Public Health'', with Kulldorff serving as one of two editors-in-chief. The journal only publishes work by members of the newly formed "Academy of Public Health,"and is a subsidiary of the Real Clear Foundation, a conservative donor funded organization. The journal has received criticism, with evolutionary biologist Carl Bergstrom describing it as, "dominated ya small clique of contrarians around the COVID pandemic," bibliometrics researcher Jens Peter Andersen describing it as "incredibly problematic," and Mallory Harris, a postdoc at the University of Maryland, stating it appears to be a "parallel structure" to facilitate research that wouldn't be accepted in other publications. In June 2025, U.S. secretary of health and human services Robert F. Kennedy Jr. named Kulldorff to the
Advisory Committee on Immunization Practices The Advisory Committee on Immunization Practices (ACIP) is a National Immunization Technical Advisory Group, committee within the United States Centers for Disease Control and Prevention (CDC) that provides advice and guidance on effective control ...
.


Views on COVID-19

In 2020, Kulldorff was invited to meet with leaders, lawyers and staff at the
American Institute for Economic Research The American Institute for Economic Research (AIER) is a classical liberal think tank located in Great Barrington, Massachusetts. It was founded in 1933 by Edward C. Harwood, an economist and investment advisor, and is a 501(c)(3) nonprofit. ...
(AIER), an American
libertarian Libertarianism (from ; or from ) is a political philosophy that holds freedom, personal sovereignty, and liberty as primary values. Many libertarians believe that the concept of freedom is in accord with the Non-Aggression Principle, according ...
think tank A think tank, or public policy institute, is a research institute that performs research and advocacy concerning topics such as social policy, political strategy, economics, military, technology, and culture. Most think tanks are non-governme ...
. Following the meeting Kulldorff took the lead in an effort to oppose lockdowns in favor of pursuing
COVID-19 Coronavirus disease 2019 (COVID-19) is a contagious disease caused by the coronavirus SARS-CoV-2. In January 2020, the disease spread worldwide, resulting in the COVID-19 pandemic. The symptoms of COVID‑19 can vary but often include fever ...
herd immunity before vaccines became available. His efforts resulted in the Great Barrington Declaration, an
open letter An open letter is a Letter (message), letter that is intended to be read by a wide audience, or a letter intended for an individual, but that is nonetheless widely distributed intentionally. Open letters usually take the form of a letter (mess ...
co-authored with Oxford's Sunetra Gupta and Stanford's Jay Bhattacharya for the AIER. The document stated that lower-risk groups would develop herd immunity through infection while vulnerable groups should be protected from the virus. The
World Health Organization The World Health Organization (WHO) is a list of specialized agencies of the United Nations, specialized agency of the United Nations which coordinates responses to international public health issues and emergencies. It is headquartered in Gen ...
, the
National Institutes of Health The National Institutes of Health (NIH) is the primary agency of the United States government responsible for biomedical and public health research. It was founded in 1887 and is part of the United States Department of Health and Human Service ...
and other public-health bodies said such a policy lacked a sound scientific basis. Scientists dismissed the policy as impossible in practice, unethical and
pseudoscientific Pseudoscience consists of statements, beliefs, or practices that claim to be both scientific and factual but are incompatible with the scientific method. Pseudoscience is often characterized by contradictory, exaggerated or unfalsifiable cl ...
, *For "unethical", ''see'' ; *for the "impossible" nature and "false promise" of focused protection, ''see'' ; *for "pseudoscience", ''see'' . warning that attempting to implement it could cause many unnecessary deaths with the potential of recurrent waves of disease spread as immunity decreases over time. Kulldorff and the other authors met with US officials of the Trump administration to share their ideas on 5 October 2020, the day after the declaration was made public. During the pandemic Kulldorff has opposed COVID-19 disease control measures. The measures opposed include lockdowns,
contact tracing In public health, contact tracing is the process of identifying people who may have been exposed to an infected person ("contacts") and subsequent collection of further data to assess transmission. By tracing the contacts of infected individua ...
, vaccine mandates, and mask mandates. He has spoken out against vaccine passports, stating they disproportionately harm the working class. Kulldorff and Bhattacharya opposed broad vaccine mandates, stating that the mortality risk is "a thousand fold higher" in older people than in younger people. He has argued against COVID vaccinations for children, saying that the risks outweigh the benefits. In an
Op-ed An op-ed, short for "opposite the editorial page," is a type of written prose commonly found in newspapers, magazines, and online publications. They usually represent a writer's strong and focused opinion on an issue of relevance to a targeted a ...
in the ''
Wall Street Journal ''The Wall Street Journal'' (''WSJ''), also referred to simply as the ''Journal,'' is an American newspaper based in New York City. The newspaper provides extensive coverage of news, especially business and finance. It operates on a subscriptio ...
'' co-authored with Jay Bhattacharya, the authors stated that COVID-19 testing should not be used to "check asymptomatic children to see if it is safe for them to come to school" because of the difference in mortality risk for young persons compared to older persons. Instead, the authors wrote that " th the new CDC guidelines, strategic age-targeted viral testing will protect older people from deadly COVID-19 exposure and children and young adults from needless school closures". On 18 March 2021, Kulldorff participated in an online roundtable with the governor of the state
Florida Florida ( ; ) is a U.S. state, state in the Southeastern United States, Southeastern region of the United States. It borders the Gulf of Mexico to the west, Alabama to the northwest, Georgia (U.S. state), Georgia to the north, the Atlantic ...
,
Ron DeSantis Ronald Dion DeSantis (; born September 14, 1978) is an American politician, attorney, and former United States Navy, naval officer serving as the 46th List of governors of Florida, governor of Florida since 2019. A member of the Republican Pa ...
, to discuss COVID-19. In the video, which was posted on
YouTube YouTube is an American social media and online video sharing platform owned by Google. YouTube was founded on February 14, 2005, by Steve Chen, Chad Hurley, and Jawed Karim who were three former employees of PayPal. Headquartered in ...
, DeSantis asked the group if children should wear masks in school and Kulldorff responded "children should not wear face masks. No. They don't need it for their own protection and they don't need it for protecting other people, either." In April, YouTube removed the recording of the roundtable, asserting it violated YouTube's policy regarding medical information. At the time the video was published, the
Centers for Disease Control The Centers for Disease Control and Prevention (CDC) is the national public health agency of the United States. It is a United States federal agency under the Department of Health and Human Services (HHS), and is headquartered in Atlanta, ...
recommended universal indoor masking for children two years and older. Kulldorff was a member of the Vaccine Safety Technical subgroup of CDC's Advisory Committee on Immunization Practices. In April 2021, he disagreed with the CDC's pause of the Johnson & Johnson vaccine rollout and argued publicly that the vaccine's benefits outweighed clotting risks, particularly for older people. In December 2021, Kulldorff published an essay for the Brownstone Institute in which he argued against children receiving vaccination against COVID-19, falsely claiming that
influenza Influenza, commonly known as the flu, is an infectious disease caused by influenza viruses. Symptoms range from mild to severe and often include fever, runny nose, sore throat, muscle pain, headache, coughing, and fatigue. These sympto ...
was a greater risk to children than COVID-19. In a critical response published in Science-Based Medicine, Jonathan Howard noted errors and factual inaccuracies in Kulldorff's essay, pointing out that while influenza was responsible for only one child death in the 2020/21 season – while public health mitigation of COVID-19 was in place – COVID-19 killed more than 1,000. In addition to this, Kulldorff's essay omitted that children who are infected with COVID-19 are at risk for rare but serious conditions, such as MIS-C, with 8,862 confirmed cases of children with MIS-C by March 2023. On 13 February 2022, Kulldorff tweeted in support of the Canada convoy protest, which was organized to protest against vaccine mandates and other government restrictions regarding COVID-19. In December 2022, Florida Gov. DeSantis named Kulldorff, Bhattacharya, and several other opponents of the scientific consensus on COVID-19 vaccines to his newly formed Public Health Integrity Committee to "offer critical assessments" of recommendations from federal health agencies.


References


External links

* {{DEFAULTSORT:Kulldorf, Martin 1962 births People from Lund Living people Umeå University alumni Cornell University alumni Biostatisticians Swedish epidemiologists Harvard Medical School faculty Swedish expatriates in the United States Spatial statisticians University of Connecticut faculty Academic staff of Uppsala University Date of birth missing (living people)