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Manfred Eigen (; 9 May 1927 – 6 February 2019) was a German biophysical chemist who won the 1967
Nobel Prize in Chemistry The Nobel Prize in Chemistry () is awarded annually by the Royal Swedish Academy of Sciences to scientists in the various fields of chemistry. It is one of the five Nobel Prizes established by the will of Alfred Nobel in 1895, awarded for outst ...
for work on measuring fast chemical reactions. Eigen's research helped solve major problems in physical chemistry and aided in the understanding of chemical processes that occur in living organisms. In later years, he explored the biochemical roots of life and evolution. He worked to install a multidisciplinary program at the Max Planck Institute to study the underpinnings of life at the molecular level. His work was hailed for creating a new scientific and technological discipline: evolutionary
biotechnology Biotechnology is a multidisciplinary field that involves the integration of natural sciences and Engineering Science, engineering sciences in order to achieve the application of organisms and parts thereof for products and services. Specialists ...
.


Education and early life

Eigen was born on 9 May 1927 in
Bochum Bochum (, ; ; ; ) is a city in North Rhine-Westphalia. With a population of 372,348 (April 2023), it is the sixth-largest city (after Cologne, Düsseldorf, Dortmund, Essen and Duisburg) in North Rhine-Westphalia, the most populous German federa ...
, the son of Ernst and Hedwig (Feld) Eigen, a chamber musician. As a child he developed a deep passion for music, and studied piano.
World War II World War II or the Second World War (1 September 1939 – 2 September 1945) was a World war, global conflict between two coalitions: the Allies of World War II, Allies and the Axis powers. World War II by country, Nearly all of the wo ...
interrupted his formal education. At age fifteen he was drafted into service in a German antiaircraft unit. He was captured by the Americans toward the end of the war. He managed to escape (he said later that escape was relatively easy), and walked hundreds of miles across defeated Germany, arriving in Göttingen in 1945. He lacked the necessary documentation for acceptance to university, but was admitted after he demonstrated his knowledge in an exam. He entered the university's first postwar class. Eigen desired to study physics, but since returning soldiers who were enrolled previously received priority, he enrolled in Geophysics. He earned an undergraduate degree and began graduate study in natural sciences. One of his advisors was
Werner Heisenberg Werner Karl Heisenberg (; ; 5 December 1901 – 1 February 1976) was a German theoretical physicist, one of the main pioneers of the theory of quantum mechanics and a principal scientist in the German nuclear program during World War II. He pub ...
, the noted proponent of the
uncertainty principle The uncertainty principle, also known as Heisenberg's indeterminacy principle, is a fundamental concept in quantum mechanics. It states that there is a limit to the precision with which certain pairs of physical properties, such as position a ...
. He received his doctorate in 1951.


Career and research

Eigen received his Ph.D. at the
University of Göttingen The University of Göttingen, officially the Georg August University of Göttingen (, commonly referred to as Georgia Augusta), is a Public university, public research university in the city of Göttingen, Lower Saxony, Germany. Founded in 1734 ...
in 1951 under supervision of Arnold Eucken. In 1964 he presented the results of his research at a meeting of the Faraday Society in London. His findings demonstrated for the first time that it was possible to determine the rates of chemical reactions that occurred during time intervals as brief as a nanosecond. Beginning in 1953 Eigen worked at the Max Planck Institute for Physical Chemistry in
Göttingen Göttingen (, ; ; ) is a college town, university city in Lower Saxony, central Germany, the Capital (political), capital of Göttingen (district), the eponymous district. The River Leine runs through it. According to the 2022 German census, t ...
, becoming its director in 1964 and joining it with the Max Planck Institute for Spectroscopy to become the Max Planck Institute for Biophysical Chemistry. He was an honorary professor of the Braunschweig University of Technology. From 1982 to 1993, Eigen was president of the German National Merit Foundation. Eigen was a member of the Board of Sponsors of ''The
Bulletin of the Atomic Scientists The ''Bulletin of the Atomic Scientists'' is a nonprofit organization concerning science and global security issues resulting from accelerating technological advances that have negative consequences for humanity. The ''Bulletin'' publishes conte ...
''. In 1967, Eigen was awarded, along with Ronald George Wreyford Norrish and
George Porter George Porter, Baron Porter of Luddenham, (6 December 1920 – 31 August 2002) was a British chemist. He was awarded the Nobel Prize in Chemistry in 1967. Education and early life Porter was born in Stainforth, near Thorne, in the then West ...
, the
Nobel Prize in Chemistry The Nobel Prize in Chemistry () is awarded annually by the Royal Swedish Academy of Sciences to scientists in the various fields of chemistry. It is one of the five Nobel Prizes established by the will of Alfred Nobel in 1895, awarded for outst ...
. They were cited for their studies of extremely fast
chemical reaction A chemical reaction is a process that leads to the chemistry, chemical transformation of one set of chemical substances to another. When chemical reactions occur, the atoms are rearranged and the reaction is accompanied by an Gibbs free energy, ...
s induced in response to very short
pulse In medicine, the pulse refers to the rhythmic pulsations (expansion and contraction) of an artery in response to the cardiac cycle (heartbeat). The pulse may be felt ( palpated) in any place that allows an artery to be compressed near the surfac ...
s of
energy Energy () is the physical quantity, quantitative physical property, property that is transferred to a physical body, body or to a physical system, recognizable in the performance of Work (thermodynamics), work and in the form of heat and l ...
. In addition, Eigen's name is linked with the theory of quasispecies, the error threshold, error catastrophe, Eigen's paradox, and the chemical hypercycle, the cyclic linkage of reaction cycles as an explanation for the
self-organization Self-organization, also called spontaneous order in the social sciences, is a process where some form of overall order and disorder, order arises from local interactions between parts of an initially disordered system. The process can be spont ...
of prebiotic systems, which he described with Peter Schuster in 1977. Eigen founded two biotechnology companies, '' Evotec'' and ''Direvo''. In 1981, Eigen became a founding member of the World Cultural Council. Eigen was a member of the
Pontifical Academy of Sciences The Pontifical Academy of Sciences (, ) is a Academy of sciences, scientific academy of the Vatican City, established in 1936 by Pope Pius XI. Its aim is to promote the progress of the mathematical, physical, and natural sciences and the study ...
even though he was an atheist. He died on 6 February 2019 at the age of 91.


Personal life

Eigen was married to Elfriede Müller. The union produced two children, a boy and a girl. He later married Ruthild Winkler-Oswatitsch, a longtime scientific partner.


Honours and awards

Eigen won numerous awards for his research including: *
Otto Hahn Prize The Otto Hahn Prize is awarded biennially jointly by the Society of German Chemists (), the German Physical Society () and the city of Frankfurt am Main for outstanding achievement in the field of chemistry, physics or applied engineering science. ...
(1962) * Elected a member of the
American Academy of Arts and Sciences The American Academy of Arts and Sciences (The Academy) is one of the oldest learned societies in the United States. It was founded in 1780 during the American Revolution by John Adams, John Hancock, James Bowdoin, Andrew Oliver, and other ...
(1964) * Elected a member of the United States
National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, NGO, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the ...
(1966) *
Nobel Prize in Chemistry The Nobel Prize in Chemistry () is awarded annually by the Royal Swedish Academy of Sciences to scientists in the various fields of chemistry. It is one of the five Nobel Prizes established by the will of Alfred Nobel in 1895, awarded for outst ...
(1967), shared with Ronald George Wreyford Norrish and
George Porter George Porter, Baron Porter of Luddenham, (6 December 1920 – 31 August 2002) was a British chemist. He was awarded the Nobel Prize in Chemistry in 1967. Education and early life Porter was born in Stainforth, near Thorne, in the then West ...
, for his studies on the kinetics of extremely fast running
chemical reaction A chemical reaction is a process that leads to the chemistry, chemical transformation of one set of chemical substances to another. When chemical reactions occur, the atoms are rearranged and the reaction is accompanied by an Gibbs free energy, ...
s with relaxation methods * Elected a member of the
American Philosophical Society The American Philosophical Society (APS) is an American scholarly organization and learned society founded in 1743 in Philadelphia that promotes knowledge in the humanities and natural sciences through research, professional meetings, publicat ...
(1968) * Member of the Soviet Academy of Sciences (now the Russian Academy of Sciences) (1976) * * Elected a Foreign Member of the Royal Society (ForMemRS) in 1973 *
Pour le Mérite The (; , ), also informally known as the ''Blue Max'' () after German WWI flying ace Max Immelmann, is an order of merit established in 1740 by King Frederick II of Prussia. Separated into two classes, each with their own designs, the was ...
(1973) *
Faraday Lectureship Prize The Faraday Lectureship Prize, previously known simply as the Faraday Lectureship, is awarded once every two years (approximately) by the Royal Society of Chemistry for "exceptional contributions to physical or theoretical chemistry".. Named aft ...
from the
Royal Society of Chemistry The Royal Society of Chemistry (RSC) is a learned society and professional association in the United Kingdom with the goal of "advancing the chemistry, chemical sciences". It was formed in 1980 from the amalgamation of the Chemical Society, the ...
in 1977 *
Austrian Decoration for Science and Art The Austrian Decoration for Science and Art () is a state decoration of the Republic of Austria and forms part of the Orders, decorations, and medals of Austria, Austrian national honours system. History The "Austrian Decoration for Science a ...
* Lower Saxony State Prize for Science (1980) *
Paul Ehrlich and Ludwig Darmstaedter Prize The Paul Ehrlich and Ludwig Darmstaedter Prize is an annual award bestowed by the since 1952 for research in medicine. It carries a monetary prize of 120,000 Euro. The prize ceremony is traditionally held on the 14th of March, the birthday of Nob ...
(1992) * Helmholtz Medal ( Berlin-Brandenburg Academy of Sciences and Humanities, 1994) * Max Planck Research Award (1994), jointly with Rudolf Rigler of the
Karolinska Institute The Karolinska Institute (KI; ; sometimes known as the (Royal) Caroline Institute in English) is a research-led medical university in Solna within the Stockholm urban area of Sweden and one of the foremost medical research institutes globally ...
* Honorary member of the Ruhr University Bochum (2001) * Lifetime Achievement Award from the Institute of Human Virology in
Baltimore Baltimore is the most populous city in the U.S. state of Maryland. With a population of 585,708 at the 2020 census and estimated at 568,271 in 2024, it is the 30th-most populous U.S. city. The Baltimore metropolitan area is the 20th-large ...
(2005) *
Wilhelm Exner Medal The Wilhelm Exner Medal has been awarded by the Austrian Industry Association, (ÖGV), for excellence in research and science since 1921. The medal is dedicated to Wilhelm Exner (1840–1931), former president of the Association, who initialize ...
(2011)


Honorary doctorates

He received 15 honorary doctorates. * Honorary Professor,
Technical University of Braunschweig TU Braunschweig (, unofficially ''University of Braunschweig – Institute of Technology'') is the oldest ' (comparable to an institute of technology in the American system) in Germany. It was founded in 1745 as Collegium Carolinum and is a membe ...
(1965) * Honorary doctorate from
Harvard University Harvard University is a Private university, private Ivy League research university in Cambridge, Massachusetts, United States. Founded in 1636 and named for its first benefactor, the History of the Puritans in North America, Puritan clergyma ...
(1966) * Honorary doctorate from Washington University in St. Louis (1966) * Honorary doctorate from the
University of Chicago The University of Chicago (UChicago, Chicago, or UChi) is a Private university, private research university in Chicago, Illinois, United States. Its main campus is in the Hyde Park, Chicago, Hyde Park neighborhood on Chicago's South Side, Chic ...
(1966) * Honorary doctorate from the
University of Nottingham The University of Nottingham is a public research university in Nottingham, England. It was founded as University College Nottingham in 1881, and was granted a royal charter in 1948. Nottingham's main campus (University Park Campus, Nottingh ...
(1968) * Honorary Professor,
University of Göttingen The University of Göttingen, officially the Georg August University of Göttingen (, commonly referred to as Georgia Augusta), is a Public university, public research university in the city of Göttingen, Lower Saxony, Germany. Founded in 1734 ...
(1971) * Honorary doctorate from
Hebrew University of Jerusalem The Hebrew University of Jerusalem (HUJI; ) is an Israeli public university, public research university based in Jerusalem. Co-founded by Albert Einstein and Chaim Weizmann in July 1918, the public university officially opened on 1 April 1925. ...
(1973) * Honorary doctorate from the
University of Hull The University of Hull is a public research university in Kingston upon Hull, a city in the East Riding of Yorkshire, England. It was founded in 1927 as University College Hull. The main university campus is located in Hull and is home to the Hu ...
(1976) * Honorary doctorate from the
University of Bristol The University of Bristol is a public university, public research university in Bristol, England. It received its royal charter in 1909, although it can trace its roots to a Merchant Venturers' school founded in 1595 and University College, Br ...
(1978) * Honorary doctorate from the
University of Debrecen The University of Debrecen ( ) is a university located in Debrecen, Hungary. It is the oldest continuously operating institution of higher education in Hungary ever since its establishment in 1538. The university has a well established progra ...
(1982) * Honorary doctorate from the
University of Cambridge The University of Cambridge is a Public university, public collegiate university, collegiate research university in Cambridge, England. Founded in 1209, the University of Cambridge is the List of oldest universities in continuous operation, wo ...
(1982) * Honorary doctorate from
Technical University of Munich The Technical University of Munich (TUM or TU Munich; ) is a public research university in Munich, Bavaria, Germany. It specializes in engineering, technology, medicine, and applied and natural sciences. Established in 1868 by King Ludwig II ...
(1983) * Honorary doctorate from the University of Bielefeld (1985) * Honorary doctorate from
Utah State University Utah State University (USU or Utah State) is a public university, public land grant colleges, land-grant research university with its main campus in Logan, Utah, United States. Founded in 1888 under the Morrill Land-Grant Acts as Utah's federal ...
(1990) * Honorary doctorate from the University of Alicante (1990) * Honorary doctorate from the
University of Coimbra The University of Coimbra (UC; , ) is a Public university, public research university in Coimbra, Portugal. First established in Lisbon in 1290, it went through a number of relocations until moving permanently to Coimbra in 1537. The university ...
, Portugal (2007) * Honorary Degree, Scripps Institute of Research (2011)


References


Bibliography

* * *
Manfred Eigen tells his life story at Web of Stories
(video) * ttp://www.vega.org.uk/video/programme/123 Interview with Manfred Eigen by Harry Kroto, NLFreeview video provided by the Vega Science Trust.
Falls ein Gott die Naturgesetze erschuf, so erschuf er auch das Leben durch Evolution
(in German) Interview with Manfred Eigen from 2004, Archive


Further reading


Obituaries

* *


External links


"The institute congratulates Manfred Eigen on his 90th birthday!"
at mpibpc.mpg.de * * including the Nobel Lecture, 11 December 1967 ''Immeasurably Fast Reactions'' {{DEFAULTSORT:Eigen, Manfred 1927 births 2019 deaths Academic staff of TU Braunschweig Foreign associates of the National Academy of Sciences Foreign members of the Royal Society Foreign members of the Russian Academy of Sciences Foreign members of the USSR Academy of Sciences Founding members of the World Cultural Council German biophysicists German atheists German Nobel laureates Max Planck Society people Members of the European Molecular Biology Organization Members of the French Academy of Sciences Members of the Pontifical Academy of Sciences Nobel laureates in Chemistry People from Bochum Scientists from the Province of Westphalia German physical chemists Recipients of the Pour le Mérite (civil class) Studienstiftung alumni University of Göttingen alumni Academic staff of the University of Göttingen Recipients of the Austrian Decoration for Science and Art Members of the German Academy of Sciences at Berlin Luftwaffenhelfer German prisoners of war in World War II held by the Soviet Union German escapees Escapees from Soviet detention Members of the American Philosophical Society Max Planck Institute directors