''Mallotus oppositifolius'' is a plant species in the genus ''
Mallotus
''Mallotus'' may refer to:
* ''Mallotus'' (fish), a fish genus in the family Osmeridae
* ''Mallotus'' (plant), a plant genus in the family Euphorbiaceae
{{genus disambiguation ...
'' found in Africa and Madagascar.
The variety ''Mallotus oppositifolius'' var. ''lindicus'' is classified in the
IUCN red list of vulnerable species of plants.
The aqueous and ethanol extracts of the plant show
antifungal
An antifungal medication, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis (thrush), serious systemic infections such as crypto ...
properties, and anti parasitic activity against
blastocystis hominis
''Blastocystis'' is a genus of single-celled heterokont parasites belonging to a group of organisms that are known as the Stramenopiles (also called Heterokonts) that includes algae, diatoms, and water molds. Blastocystis consists of several ...
.
The
bioassay-guided fractionation of an ethanol extract of the leaves and inflorescence of ''M. oppositifolius'' collected in Madagascar led to the isolation of the two new bioactive dimeric phloroglucinols
mallotojaponins B and
C, together with
mallotophenone. These compounds show
antiproliferative
Cytostasis (cyto – cell; stasis – stoppage) is the inhibition of cell growth and multiplication. Cytostatic refers to a cellular component or medicine that inhibits cell division.
Cytostasis is an important prerequisite for structured multic ...
and
antiplasmodial
''Plasmodium'' is a genus of unicellular eukaryotes that are obligate parasites of vertebrates and insects. The life cycles of ''Plasmodium'' species involve development in a blood-feeding insect host which then injects parasites into a verteb ...
(antimalarial) activities.
References
External links
''Mallotus oppositifolius'' at gbif.org''Mallotus oppositifolius'' at tropicos.org*
oppositifolius
Plants described in 1865
Flora of Africa
Flora of Madagascar
{{Euphorbiaceae-stub