Malcolm Edward Molyneux (20 November 1943 - 16 November 2021) was a British professor tropical medical researcher who specialised in
malaria
Malaria is a Mosquito-borne disease, mosquito-borne infectious disease that affects vertebrates and ''Anopheles'' mosquitoes. Human malaria causes Signs and symptoms, symptoms that typically include fever, Fatigue (medical), fatigue, vomitin ...
, especially cerebral malaria. He spent much of his career in Malawi, and was partially responsible for the establishment of the
University of Malawi College of Medicine. He and other researchers developed the
Blantyre coma scale
The Blantyre coma scale is a modification of the Pediatric Glasgow Coma Scale, designed to assess malarial coma in children.
It was designed by Terrie Taylor and Malcolm Molyneux in 1987, and named for the Malawi
Malawi, officially the ...
, a scale to assess the severity of comas induced by malaria in children. For his work in the field, he was elected a fellow of the
Academy of Medical Sciences
The Academy of Medical Sciences is an organisation established in the UK in 1998. It is one of the four UK National Academy, National Academies, the others being the British Academy, the Royal Academy of Engineering and the Royal Society.
Its ...
in 1998 and appointed an
OBE
The Most Excellent Order of the British Empire is a British order of chivalry, rewarding valuable service in a wide range of useful activities. It comprises five classes of awards across both civil and military divisions, the most senior two o ...
in 2006.
During his career he worked at the
Queen Elizabeth Central Hospital
The Queen Elizabeth Central Hospital, is a tertiary referral and teaching hospital in Malawi, situated in Blantyre. It provides care to the surrounding district hospitals, health clinics, and private medical facilities. Officially, the hospital ...
in Blantyre, Malawi, and the
Liverpool School of Tropical Medicine
The Liverpool School of Tropical Medicine (LSTM) is a post-graduate teaching and research institution based in Liverpool, England, established in 1898. It was the first institution in the world dedicated to the study of tropical medicine. LSTM ...
in Liverpool, England, where he was given the title of Emeritus Professor of Tropical Medicine. He also worked as an editor for ''
Malawi Medical Journal'' and ''Tropical Doctor.''
Education
Malcom Molyneux earnt degrees in natural science and medicine from the
University of Cambridge
The University of Cambridge is a Public university, public collegiate university, collegiate research university in Cambridge, England. Founded in 1209, the University of Cambridge is the List of oldest universities in continuous operation, wo ...
, and graduated in 1967.
He then attended
Barts and The London School of Medicine and Dentistry
Barts and The London School of Medicine and Dentistry, commonly known as Barts or BL, is a medical school, medical and dental school in London, England. The school is part of Queen Mary University of London, a constituent college of the federal ...
for his medical training.
He subsequently completely a PhD on the viruses and liver disease in Malawi.
In 2019, he was given an honorary doctorate of science by the
Liverpool School of Tropical Medicine
The Liverpool School of Tropical Medicine (LSTM) is a post-graduate teaching and research institution based in Liverpool, England, established in 1898. It was the first institution in the world dedicated to the study of tropical medicine. LSTM ...
.
Career
After graduating, Molyneux moved to Malawi and in 1974 and began work as a doctor in St Luke's Hospital,
Malosa.
After a year, he transferred and started to work as a consultant at the
Queen Elizabeth Central Hospital
The Queen Elizabeth Central Hospital, is a tertiary referral and teaching hospital in Malawi, situated in Blantyre. It provides care to the surrounding district hospitals, health clinics, and private medical facilities. Officially, the hospital ...
in
Blantyre
Blantyre is Malawi's centre of finance and commerce, and its second largest city, with a population of 800,264 . It is sometimes referred to as the commercial and industrial capital of Malawi as opposed to the political capital, Lilongwe. It is ...
.
He became a fellow of the
Royal Society of Tropical Medicine and Hygiene
The Royal Society of Tropical Medicine and Hygiene, more commonly known by its acronym RSTMH, was founded in 1907 by Sir James Cantlie and George Carmichael Low. Sir Patrick Manson, the Society's first President (1907–1909), was recognised as ...
in 1976. Molyneux left Malawi in 1984 and moved back to England
after being invited by
Herbert Michael Gilles to work a lecturer at
Liverpool School of Tropical Medicine
The Liverpool School of Tropical Medicine (LSTM) is a post-graduate teaching and research institution based in Liverpool, England, established in 1898. It was the first institution in the world dedicated to the study of tropical medicine. LSTM ...
.
There he worked research on malaria, especially
cerebral malaria
Malaria is a mosquito-borne infectious disease that affects vertebrates and '' Anopheles'' mosquitoes. Human malaria causes symptoms that typically include fever, fatigue, vomiting, and headaches. In severe cases, it can cause jaundice, s ...
in children,
and helped to establish a research ward connected to the Queen Elizabeth Central Hospital's paediatric department in 1990.
He and fellow researchers Terrie Taylor and Jack Wirima developed the
Blantyre coma scale
The Blantyre coma scale is a modification of the Pediatric Glasgow Coma Scale, designed to assess malarial coma in children.
It was designed by Terrie Taylor and Malcolm Molyneux in 1987, and named for the Malawi
Malawi, officially the ...
, a scale to assess the severity of comas induced by malaria in children.
In 1991, Molyneaux was invited to help set up the
University of Malawi College of Medicine,
whose creation he had recommended, alongside
Hetherwick Ntaba and
Peter Chimimba, in 1985.
In 1995, he moved back to Malawi and began work as the director of the newly-established Malawi-Liverpool
Wellcome Trust
The Wellcome Trust is a charitable foundation focused on health research based in London, United Kingdom. It was established in 1936 with legacies from the pharmaceutical magnate Henry Wellcome (founder of Burroughs Wellcome, one of the predec ...
.
In 1998 he was elected as a fellow of the
Academy of Medical Sciences
The Academy of Medical Sciences is an organisation established in the UK in 1998. It is one of the four UK National Academy, National Academies, the others being the British Academy, the Royal Academy of Engineering and the Royal Society.
Its ...
.
In 2006, he was awarded an
OBE
The Most Excellent Order of the British Empire is a British order of chivalry, rewarding valuable service in a wide range of useful activities. It comprises five classes of awards across both civil and military divisions, the most senior two o ...
for his work in Malawi healthcare.
He retired the next year
and was given the title of Emeritus Professor of Tropical Medicine at the Liverpool School of Tropical Medicine.
Apart from his work in research medicine, Molyneaux also founded ''Medical Quarterly'', later the ''
Malawi Medical Journal'', in 1976,
and worked there as an editor chief of the from 1980 to 1984,
and as editor of the ''
Tropical Doctor'' from 1985 to 1992.
He worked for ''
The Lancet
''The Lancet'' is a weekly peer-reviewed general medical journal, founded in England in 1823. It is one of the world's highest-impact academic journals and also one of the oldest medical journals still in publication.
The journal publishes ...
'' as an ombudsman, and took part on World Health Organization committees and the Malaria Control Programme in Malawi.
Additionally, he was the chairman of a committee overseeing the safety the then-untested malaria vaccine
RTS,S
RTS,S/AS01 (trade name Mosquirix) is a recombinant protein-based malaria vaccine. It is one of two malaria vaccines approved (the other is R21/Matrix-M). , the vaccine has been given to 1million children living in areas with moderate-to-high ...
.
In 1995, he wrote chapters on malaria, fevers,
amoebiasis
Amoebiasis, or amoebic dysentery, is an infection of the intestines caused by a parasitic amoeba '' Entamoeba histolytica''. Amoebiasis can be present with no, mild, or severe symptoms. Symptoms may include lethargy, loss of weight, colon ...
,
giardiasis
Giardiasis is a parasitic disease caused by the protist enteropathogen ''Giardia duodenalis'' (also known as ''G. lamblia'' and ''G. intestinalis''), especially common in children and travellers. Infected individuals experience steatorrhea, a typ ...
,
balantidiasis
Balantidiasis is a protozoan infection caused by infection with ''Balantidium coli''.
History
The first study to generate balantidiasis in humans was undertaken by Cassagrandi and Barnagallo in 1896. However, this experiment was not successful in ...
,
anaemia
Anemia (also spelt anaemia in British English) is a blood disorder in which the blood has a reduced ability to carry oxygen. This can be due to a lower than normal number of red blood cells, a reduction in the amount of hemoglobin availab ...
, and
flukes for the fourth edition of ''
Lecture Notes on Tropical Medicine''. For the fifth edition, he wrote the chapter "Malaria".
In 2009, he was awarded the
Sir Rickard Christophers Medal.
Personal life
Malcolm Edward Molyneux was born on 20 November 1943
in the Belgian Congo to missionaries Colin and Joyce () Molyneux. As a child he attended the Sakeji School, a boarding school in what was then Northern Rhodesia,
but at the age of 13 went to board at
Eltham College
Eltham College is a private day school situated in Mottingham, southeast London. Eltham and Mottingham once formed part of the same parish, hence its name. It is a member of The Headmasters' and Headmistresses' Conference (HMC).
Early history ...
in London.
While studying at Barts, Molyneaux met his future wife,
Elizabeth Neech. They married in 1969
and, by 1974, had two children.
Molyneaux was diagnosed with
chronic lymphocytic leukaemia
Chronic lymphocytic leukemia (CLL) is a type of cancer that affects the blood and bone marrow. In CLL, the bone marrow makes too many lymphocytes, which are a type of white blood cell. In patients with CLL, B cell lymphocytes can begin to ...
in the 1990s and with
aggressive lymphoma in 2013.
He moved back to Liverpool in 2015,
where he died on 16 November 2021 at the age of 77.
At the time of his death he had three children and one grandchild.
Publications
Books
*
*
Papers
*
*
Awards and honours
* 1998: Fellow of the
Academy of Medical Sciences
The Academy of Medical Sciences is an organisation established in the UK in 1998. It is one of the four UK National Academy, National Academies, the others being the British Academy, the Royal Academy of Engineering and the Royal Society.
Its ...
* 2006:
Order of the British Empire
The Most Excellent Order of the British Empire is a British order of chivalry, rewarding valuable service in a wide range of useful activities. It comprises five classes of awards across both civil and military divisions, the most senior two o ...
* 2009:
Sir Rickard Christophers Medal
References
{{DEFAULTSORT:Molyneux, Malcolm
2021 deaths
1943 births
Academics of the Liverpool School of Tropical Medicine
Officers of the Order of the British Empire
Malariologists
20th-century British scientists
21st-century British scientists
20th-century British medical doctors